Interstitial lung disease
Therapeutic area
Pulmonology
Rare disease
Yes
- Definition
- A diverse group of lung diseases that affect the lung parenchyma. They are characterized by an initial inflammation of pulmonary alveoli that extends to the interstitium and beyond leading to diffuse pulmonary fibrosis. Interstitial lung diseases are classified by their etiology (known or unknown causes), and radiological-pathological features.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Interstitial lung disease
- Therapeutic area
- Pulmonology
- interstitial lung disease
- ILD
- interstitial lung disease
- All therapeutic areas
- Pulmonology
- Severity
- Severe
- MONDO ID
- MONDO:0015925
- Parent condition
- MONDO:0005275
Related records
Broader conditions (6)
- Disease
- Disease by body system or component
- Human disease
- Lower respiratory tract disorder
- Lung disorder
- Respiratory system disorder
Narrower conditions (97)
- Adult pulmonary Langerhans cell histiocytosis
- Alveolar capillary dysplasia with misalignment of pulmonary veins
- Anthracosilicosis
- Anthracosis
- Asbestosis
- Bagassosis
- Baritosis
- Bird fancier's lung
- Bronchiolitis obliterans syndrome
- Bronchiolocentric pattern of interstitial pneumonia
- Byssinosis
- Caplan syndrome
- Cellular interstitial pneumonitis
- Chronic beryllium disease
- Chronic pneumonitis of infancy
- Congenital chylothorax
- Congenital emphysematous lung disease due to Filamin A loss-of-function variant
- Cork-handlers' disease
- Diffuse pulmonary fibrosis
- Drug or radiation exposure-related interstitial lung disease
Trials (428)
- "Diagnostic Yield and Safety of Transbronchial Lung Biopsy Using Cryoprobes Versus Conventional Forceps.
- 129Xe MRI Cardiopulmonary
- A Clinical Trial for CTD-ILD Treatment
- A Cohort of Patients With Phenotyped Diffuse Interstitial Lung Disease With Longitudinal Follow-up
- A Home-based Physical Activity Programme for Patients With Advanced Interstitial Lung Diseases (iLiFE)
- A Multicenter Prospective Study of Risk Factors in Progressive Pulmonary Fibrosis
- A Non-pharmacological Cough Control Therapy
- A Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Qifangfeixian Granules in the Treatment of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD)
- A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis
- A Study of BIO 300 and Thoracic Radiation Therapy in People With Non-Small Cell Lung Cancer and Interstitial Lung Disease
- A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
- A Study of Mosliciguat in PH-ILD
- A Study of the Natural Progression of Interstitial Lung Disease (ILD)
- A Study of the Pharmacokinetics and Safety of Single-dose Inhaled RJ026 in Healthy Volunteers and Patients With Interstitial Lung Disease
- A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension
- A Study on the Efficacy and Safety of JAK Inhibitors Versus Calcineurin Inhibitors as Initial Therapy for Interstitial Lung Disease Associated With Antisynthetase Syndrome
- A Study to Characterize the Disease Behavior of Idiopathic Pulmonary Fibrosis (IPF) and Interstitial Lung Disease (ILD) During the Peri-Diagnostic Period
- A Study to Characterize the Safety, PK and Biological Activity of CC-930 in Idiopathic Pulmonary Fibrosis (IPF)
- A Study to Evaluate the Diagnostic Performance of Portable Oscillometry Across Chronic Respiratory Diseases
- A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients
Approved drugs (1)
- Nintedanib esylate
Drugs in development (24)
- Abituzumab Phase 2
- AD-214 Phase 1
- Admilparant Phase 1
- Amitriptyline Phase 2
- Azathioprine Phase 2
- Belimumab Phase 3
- Duloxetine Phase 2
- Fentanyl citrate Phase 3
- Gadoterate meglumine Phase 2
- Hydroxychloroquine Early phase 1
- Hydroxychloroquine sulfate Phase 2
- Mycophenolate mofetil Phase 3
- Nerandomilast Phase 3
- Nintedanib Phase 3
- Pirfenidone Phase 2
- Pomalidomide Phase 2
- Rituximab Phase 3
- Sodium chloride Phase 2
- Tadalafil Phase 3
- Transcrocetinate sodium Phase 2
Other linked drugs (5)
- Betamethasone
- Dexamethasone
- Ipratropium bromide
- Prednisolone
- Xenon