> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/iga-glomerulonephritis-f6f68a56-7253-54d9-9456-5d9ece4d1a52
> Record changed: 2026-10-13

# IgA glomerulonephritis

Therapeutic area

Nephrology

Rare disease

Yes

## Definition and classification

**Definition**

Inflammation of a specific segment of glomeruli within the kidney.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

IgA glomerulonephritis

**Therapeutic area**

Nephrology

### Alternative names (5)

- IgA glomerulonephritis
- Berger's disease
- IgA Nephropathy
- IgA glomerulonephritis
- IgA nephropathy

## Clinical profile

**All therapeutic areas**

- Nephrology

**Severity**

Severe

### Disease mechanisms (3)

- Genetic
- Hereditary
- Inflammatory

## Identifiers

**MONDO ID**

MONDO:0005342

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005342)

**Parent condition**

MONDO:0002462

## Related records

### Broader conditions (15)

- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Disease by etiologic mechanism
- Disease of genetic or genomic mechanism
- Glomerular disorder
- Glomerulonephritis
- Hereditary disease
- Hereditary nephritis
- Human disease
- Inflammatory disease
- Inherited kidney disorder
- [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md)
- Nephritis
- [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md)

### Trials (164)

- "Steroids and Azathioprine Versus Steroids Alone in IgAN"
- A Clinical Research on the Use of Fecal Bacteria Transplantation for Treatment of IgA Nephropathy
- A Clinical Study Evaluating the Safety and Efficacy of GT719 Universal Cell Injection in the Treatment of Immune-mediated Kidney Diseases
- A Clinical Study of SCTC21C in Participants With Plasma Cell-driven Autoimmune Diseases
- A Clinical Study to Evaluate the Effect of Food on the Pharmacokinetic Profiles of HRS-5965 Capsules in Healthy Subjects
- A Controlled Study of Uric Acid on the Progression of IgA Nephropathy
- A First in Human Study to Evaluate Safety, Tolerability, Pharmacology of HS-10390 in Healthy Subjects
- A Multi-center Open Label Prospective Study on Early Initiation of Targeted-release Formulation of Budesonide in Patients With Primary IgA Nephropathy
- A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
- A Phase 2 Trial of the Safety and Efficacy of Bardoxolone Methyl in Patients With Rare Chronic Kidney Diseases - PHOENIX
- A Phase IIa Clinical Study of RG002C0106 Injection in Subjects With Primary IgA Nephropathy
- A Phase IIa Study in Primary IgA Nephropathy Patients
- A Randomized, Controlled Clinical Study of Rituximab in Treatment of Primary IgA Nephropathy
- [A Rollover Study to Evaluate the Long-Term Safety and Efficacy of Atacicept](https://trialight.com/data/trial/a-rollover-study-to-evaluate-the-long-term-safety-and-9dbe3a47-27e6-4d34-840c-23f919cece2a.md)
- A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.
- A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)
- A Study of JADE101 in Participants With Immunoglobulin A Nephropathy
- A Study of Probiotics in IgA Nephropathy
- A Study of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment
- A Study of SC0062 Capsule for the Treatment of IgA Nephropathy with Proteinuria

### Approved drugs (3)

- [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md)
- Iptacopan hydrochloride
- Sparsentan

### Drugs in development (45)

- Acetoside Phase 2
- Aliskiren Phase 3
- [Atacicept](https://trialight.com/data/asset/atacicept-58997791-8042-4d0f-ac69-564cf9e78d1d.md) Phase 3
- Atorvastatin calcium Phase 2
- Atrasentan Phase 3
- Avacopan Phase 2
- Azathioprine Phase 3
- Batiraxcept Phase 2
- Blisibimod Phase 3
- Cemdisiran Phase 2
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md) Phase 3
- Enalapril Phase 2
- Felzartamab Phase 2
- [Finerenone](https://trialight.com/data/asset/finerenone-e8453ce2-da00-4096-b589-903ae1d466ba.md) Phase 3
- Fostamatinib Phase 2
- Fostamatinib disodium Phase 2
- Hydroxychloroquine Phase 2
- Icosapent Phase 3
- Iptacopan Phase 3

### Other linked drugs (2)

- Allopurinol
- Calcitriol

---

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