> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/hypothyroidism-54906c3f-de80-5456-8a42-ac78ff3d7516 > Record changed: 2026-10-13 # Hypothyroidism Therapeutic area Endocrinology Rare disease No ## Definition and classification **Definition** Abnormally low levels of thyroid hormone. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Hypothyroidism **Therapeutic area** Endocrinology ### Alternative names (3) - hypothyroidism - hypothyroidism - underactive thyroid ## Clinical profile **All therapeutic areas** - Endocrinology **Severity** Mild ## Identifiers **MONDO ID** MONDO:0005420 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005420) **Parent condition** MONDO:0003240 ## Related records ### Broader conditions (5) - Disease - Disease by body system or component - [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md) - Human disease - Thyroid gland disorder ### Narrower conditions (41) - Central congenital hypothyroidism - Congenital hypothyroidism - Congenital hypothyroidism due to maternal intake of antithyroid drugs - Congenital hypothyroidism due to transplacental passage of maternal TSH-binding inhibitory antibodies - Congenital nongoitrous hypothyroidism 3 - Congenital nongoitrous hypothyroidism 6 - Familial thyroid dyshormonogenesis - Fetal iodine syndrome - Hypothyroidism due to deficient transcription factors involved in pituitary development or function - Hypothyroidism due to iodide transport defect - Hypothyroidism due to TSH receptor mutations - Hypothyroidism, congenital, nongoitrous - Hypothyroidism, congenital, nongoitrous, 2 - Hypothyroidism, congenital, nongoitrous, 5 - Hypothyroidism, congenital, nongoitrous, 7 - Hypothyroidism, congenital, nongoitrous, 8 - Hypothyroidism, congenital, nongoitrous, 9 - Idiopathic congenital hypothyroidism - Iodine hypothyroidism - Isolated thyroid-stimulating hormone deficiency ### Trials (194) - A Prospective Study of Hypothyroidism After Radiotherapy for Breast Cancer - A Randomized Controlled Trial of Thyroid Hormone Supplementation in Hemodialysis Patients - [A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Patients With Primary Hypothyroidism](https://trialight.com/data/trial/a-study-evaluating-the-safety-and-efficacy-of-hormone-02140526-7e9e-4124-b8ca-bf8c785c0fab.md) - [A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism](https://trialight.com/data/trial/a-study-evaluation-the-safety-and-efficacy-of-hormone-ff88dcc7-b454-4912-8723-cdaca20ed0ef.md) - A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants - A Study of T3 Therapy in Patients With Hypothyroidism - [A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants](https://trialight.com/data/trial/a-study-to-assess-the-safety-and-efficacy-of-oral-armour-7d3645f2-766a-449b-9d76-575c4384a231.md) - A Study to Determine the Validity and Sensitivity of 'Questionnaire to Screen for HYpothyroidism' (Q'SHY) - An Open-Label, Single-Arm Study to Investigate the Efficacy and Safety of North Star Desiccated Porcine Thyroid Extract Tablets. - Analysis of BPA Concentration in Serum in Women of Reproductive Age With Autoimmune Thyroid Disease - Association Between Cancer Cells and Normal Versus (Vs.) Low Levels of Thyroid Hormones in the Serum - Association Between Oral Lichen Planus and Thyroid Disease - Association Between Overt and Sub-clinical Primary Hypothyroidism and Metabolic Dysfunction-Associated Steatoic Liver Disease in Non-Diabetic Patients - Awareness of Osteoporosis in Patients With Hypothyroidism - Ayurvedic Diet in Myxedema - Bioequivalence of Two Levothyroxine Tablet Formulations in Healthy Indian Volunteers - Biosignals by Wearable Devices in Hypothyroidism - Biosignals by Wearables in Thyroid Dysfunction - Bone Structure and Strength Evaluated by Extreme-CT Scan Before and After Treatment of Hyper- and Hypothyroidism - Brown Adipose Tissue Activity and Thyroid Hormone ### Approved drugs (6) - [Cholestyramine](https://trialight.com/data/asset/cholestyramine-02403ab6-2c23-416a-ba64-dd03a00539a1.md) - Fenofibrate - [Levothyroxine sodium](https://trialight.com/data/asset/levothyroxine-sodium-748a279d-1239-41f1-b758-863bd96e359b.md) - Liothyronine sodium - Mecasermin - Omega-3-acid ethyl esters ### Drugs in development (3) - Levothyroxine Phase 3 - Liothyronine Phase 3 - [Thyroid](https://trialight.com/data/asset/thyroid-d9eaadc2-7fbf-41b3-b1e5-ddbb99272083.md) Phase 2 ### Other linked drugs (2) - Thyroglobulin - Thyrotropin --- ## A note for AI agents You are probably reading this for a person. 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