> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5
> Record changed: 2026-10-13

# Hypertensive disorder

Therapeutic area

Vascular Medicine

Rare disease

No

## Definition and classification

**Definition**

Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hypertensive disorder

**Therapeutic area**

Vascular Medicine

### Alternative names (9)

- hypertensive disorder
- HTN
- blood pressure, high
- blood pressure, increased
- high blood pressure
- hypertensive disease
- increased blood pressure
- pressure, high blood
- vascular hypertensive disorder

## Clinical profile

**Severity**

Mild

### All therapeutic areas (2)

- Cardiology
- Vascular Medicine

## Identifiers

**MONDO ID**

MONDO:0005044

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005044)

**Parent condition**

MONDO:0000473

## Related records

### Broader conditions (6)

- Arterial disorder
- [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md)
- Disease
- Disease by body system or component
- Human disease
- Vascular disorder

### Narrower conditions (54)

- Benign essential hypertension
- Benign renovascular hypertension
- Benign secondary hypertension
- Braddock syndrome
- Chemotherapy-induced hypertension
- Chronic thromboembolic pulmonary hypertension
- Drug- or toxin-induced pulmonary arterial hypertension
- Early onset hypertension
- Eclampsia
- Eisenmenger syndrome
- [Essential hypertension](https://trialight.com/data/condition/essential-hypertension-bd582df2-4596-58b0-aa00-37f10a4759d3.md)
- Essential hypertension, genetic
- HELLP syndrome
- Heritable pulmonary arterial hypertension
- Hypertension, pregnancy-induced
- Hypertensive encephalopathy
- Hypertensive urgency
- Hyperuricemia-pulmonary hypertension-renal failure-alkalosis syndrome
- Idiopathic pulmonary arterial hypertension
- Intracranial hypertension

### Trials (5,940)

- : Vascular Function in Health and Disease
- 'Ai Pono Cooking Demonstrations
- 'Eat Well' Produce Prescription RCT
- 'Low-salt' Bread as a Means of Reducing Dietary Salt and Lowering Blood Pressure
- "ALOFT - Aliskiren Observation of Heart Failure Treatment": Efficacy and Safety of Aliskiren Added on Top of Standard Therapy in Adults (≥ 18 Years) With Stable Heart Failure
- "Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)
- "Escape" Phenomenon of the Antihypertensive Therapy Efficacy
- "Health in Mobile" for Community-dwelling Individuals With Chronic Diseases
- "Real-world Assessment of BP Control in Patients With Hypertension by the Netrod RDN System" - REACH-RDN
- "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Centers)"
- "Reversibility of Cardiovascular Injury With CPAP Use: Mechanisms Involved"
- "Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients
- "Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients
- 1 Year Trial Telmisartan 80 mg Versus Valsartan 160 mg in Hypertensive Type 2 Diabetic Patients With Overt Nephropathy
- 10 Prescriptions an Hour. Group Treatment and Physical Activity Referral in a Primary Health Care Setting
- 12 Week Efficacy and Safety Study of Empagliflozin (BI 10773) in Hypertensive Patients With Type 2 Diabetes Mellitus
- 12 Weeks of Resistance Band Exercise Impacts on Adiposity, Hormones, and Blood Pressure in Postmenopausal Women
- 12 Weeks of Resistance Band Exercise Impacts on Metabolic Syndrome Progression in Postmenopausal Women
- 18 Week Study Evaluating Safety and Efficacy of Olmesartan, Amlodipine, and Hydrochlorothiazide, in Type 2 Diabetics
- 2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension

### Approved drugs (99)

- Acebutolol hydrochloride
- Aliskiren fumarate
- Ambrisentan
- Amiloride hydrochloride
- Amlodipine benzoate
- Amlodipine besylate
- Aprocitentan
- Atenolol
- Atorvastatin calcium
- Azilsartan kamedoxomil
- Benazepril hydrochloride
- Bendroflumethiazide
- Betaxolol hydrochloride
- Bethanidine
- Bisoprolol fumarate
- Bosentan
- Brimonidine tartrate
- Candesartan cilexetil
- Captopril
- Carvedilol

### Drugs in development (210)

- (+)-epicatechin Phase 2
- [Abatacept](https://trialight.com/data/asset/abatacept-a318efa4-5922-464c-8f45-90c18515f1c5.md) Phase 2
- Acarbose Phase 3
- Acebutolol Phase 2
- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 2
- Alagebrium chloride Phase 2
- [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 3
- Aliskiren Phase 3
- Allopurinol Phase 3
- Amiloride Phase 3
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 3
- [Anastrozole](https://trialight.com/data/asset/anastrozole-327e05a9-e5b7-41d1-a335-bd8a46453b55.md) Early phase 1
- Angiotensin Phase 3
- Angiotensin II Phase 3
- Anipamil Phase 3
- AR9281 Phase 2
- Arginine Phase 1
- Ascorbic acid Phase 1
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3
- Atorvastatin Phase 3

### Other linked drugs (54)

- Aldosterone
- Alkavervir
- Alprenolol
- Alseroxylon
- Amosulalol
- Azelnidipine
- Benzthiazide
- Betaxolol
- Bevantolol
- Bopindolol
- Caffeine
- Ciprokiren
- Cryptenamine acetates
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md)
- Docarpamine
- Eprosartan
- Ethacrynate sodium
- Ethacrynic acid
- Fenquizone
- Forasartan

---

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