> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hyperlipidemia-bd121998-6952-5bac-beaa-6b00584851e2
> Record changed: 2026-11-04

# Hyperlipidemia

Therapeutic area

Metabolic Disease

Rare disease

No

## Definition and classification

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hyperlipidemia

**Therapeutic area**

Metabolic Disease

### Alternative names (14)

- hyperlipidemia
- Hypercholesterolemia and Hyperlipidemia
- hyperlipidemia (disease)
- Hyperlipidemia (E.G., Hypercholesterolemia)
- Hyperlipidemia and Mixed Dyslipidemia
- Hypertension and Hyperlipidemia
- Hypertension, Hyperlipidemia
- Lipemia
- Lipidemia
- Refractory Hyperlipidemia
- hyperlipemia
- hyperlipemias
- lipemias
- lipidemias

## Clinical profile

**All therapeutic areas**

- Metabolic Disease

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021187)

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0021187

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021187)

**Parent condition**

MONDO:0005066

## Related records

### Broader conditions (4)

- Disease
- Disease by developmental or physiological process
- Human disease
- [Metabolic disease](https://trialight.com/data/condition/metabolic-disease-3d73c19d-b8c8-5be8-add5-77c7d794dacd.md)

### Narrower conditions (19)

- Cholesterol-ester transfer protein deficiency
- Familial apolipoprotein C-II deficiency
- [Familial hypercholesterolemia](https://trialight.com/data/condition/familial-hypercholesterolemia-ee6bd6b4-71cd-509a-9360-eb8a7c2bd428.md)
- Familial hyperlipidemia
- Familial lipoprotein lipase deficiency
- Homozygous familial hypercholesterolemia
- Hyperalphalipoproteinemia
- Hypercholesterolemia due to cholesterol 7alpha-hydroxylase deficiency
- Hypercholesterolemia, autosomal dominant, 3
- Hypercholesterolemia, autosomal dominant, type B
- Hypercholesterolemia, familial, 1
- Hypercholesterolemia, familial, 4
- Hyperlipidemia due to hepatic triglyceride lipase deficiency
- Hyperlipidemia, combined, 2
- Hyperlipidemia, familial combined, LPL related
- Hyperlipoproteinemia type 3
- Hyperlipoproteinemia type V
- Hyperlipoproteinemia, type 1D
- Laminopathy type Decaudain-Vigouroux

### Trials (1,898)

- "Phospholipovit" vs Placebo in Patients With Combined Hyperlipidemia
- "Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Coronary Artery Bypass Graft Patients or Post Percutaneous Coronary Intervention Patients
- "Smart Family Doctor" Assisted Comprehensive Management of Secondary Prevention Among Post Revascularization Patients
- (H.E.L.P.)Apheresis Therapy to Compare the Reduction of LDL (Low Density Lipoprotein) Cholesterol
- \[E\]PANOVA Combined With a \[S\]TATIN in \[P\]ATIENTS With HYPERT\[R\]IGLYCER\[I\]DEMIA to Reduce Non-HDL CHOLES\[T\]EROL
- 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe
- 2-HOBA Supplementation in People With Elevated Lipoprotein(a)
- A 10-12 Week Study to Evaluate the Safety and Efficacy of 320 mg Valsartan and 80 mg Simvastatin in Combination and as Monotherapies in Treating Hypertension and Hypercholesterolemia
- A 12 Week Study of MK0653A in Patients Who Have Been Hospitalized for a Possible Heart Problem (0653A-808)
- A 12 Week, 3-Period Study to Evaluate the Effects of a Dietary Supplement on Lipid Metabolism
- A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244)
- A 12-Week, Phase 2 Study of Gemcabene in Hypercholesterolemia Patients on Stable Moderate and High-Intensity Statins
- A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to Atorvastatin
- A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy Subjects
- A 4-week, Randomized, Placebo-Controlled, Double-Blind, Efficacy and Safety Study of HS-25 in Adults With Primary Hypercholesterolemia
- A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245)
- A 6-Month Consumer Behavior Study of a Self-Management System (0803-084)(COMPLETED)
- A Brief Intervention to Improve Medication Knowledge and Adherence Among Family Medicine Patients in South Texas
- A CCTA Imaging Trial to Evaluate the Effect of Obicetrapib/Ezetimibe on Coronary Plaque
- A Change in Diet May Decrease the Negative Consequences of Chronic Sleep Deprivation

### Approved drugs (14)

- Amlodipine besylate
- Atorvastatin calcium
- Ezetimibe
- Icosapent ethyl
- Niacin
- Pemafibrate
- Pitavastatin calcium
- Pitavastatin magnesium
- Pitavastatin sodium
- Rosuvastatin calcium
- [Semaglutide](https://trialight.com/data/asset/semaglutide-0f0980aa-d386-4209-8f14-80da83c40d80.md)
- Simvastatin
- Sitagliptin phosphate
- [Tirzepatide](https://trialight.com/data/asset/tirzepatide-eed85871-eb9c-4712-9102-badfdd99a720.md)

### Drugs in development (65)

- [Alirocumab](https://trialight.com/data/asset/alirocumab-94bb5dc8-32f2-4ed6-a82e-b554472e2cd5.md) Phase 1
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 1
- Amlodipine maleate Phase 3
- Anacetrapib Phase 2
- Antroquinonol Phase 2
- Atazanavir Phase 3
- Atorvastatin Phase 3
- Bempedoic acid Phase 3
- Berberine Phase 2
- Berberine sulfate Phase 2
- Bococizumab Phase 3
- Cholecalciferol Phase 1
- COENZYME\_A Phase 3
- [Dalcetrapib](https://trialight.com/data/asset/dalcetrapib-cc01e1b4-85ba-45ed-8edb-c960ab8aa4fb.md) Phase 2
- Dextrose Phase 2
- [Enlicitide](https://trialight.com/data/asset/enlicitide-35a80769-a661-4011-98bb-972a4010c4e6.md) Phase 3
- Enlicitide chloride Phase 3
- Epigalocatechin gallate Phase 2
- Evacetrapib Phase 3
- [Evolocumab](https://trialight.com/data/asset/evolocumab-ece543fe-0502-44c3-bef4-ec566503cced.md) Phase 3

### Other linked drugs (10)

- Acipimox
- Calcium polycarbophil
- Colesevelam hydrochloride
- Exenatide
- Lactobacillus acidophilus
- [Metformin](https://trialight.com/data/asset/metformin-0292cbe3-3a2f-4db7-b783-270ef048c3b4.md)
- Omega-3-acid ethyl esters
- Pioglitazone
- Policosanol
- Withanolide D

---

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