> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hormone-receptor-positive-breast-cancer-1615b277-fa91-513c-addf-371a0c1fe840
> Record changed: 2026-10-13

# Hormone receptor-positive breast cancer

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A breast carcinoma which is positive for expression of estrogen receptor (ER), progesterone receptor (PR), and is negative for expression of human epidermal growth factor receptor 2 (HER2).

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hormone receptor-positive breast cancer

**Therapeutic area**

Oncology

### Alternative names (3)

- hormone receptor-positive breast cancer
- HR-positive HER2-negative breast cancer
- hormone receptor positive breast cancer

## Clinical profile

**All therapeutic areas**

- Oncology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0700079

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0700079)

**Parent condition**

MONDO:0000615

## Related records

### Broader conditions (20)

- [Breast cancer](https://trialight.com/data/condition/breast-cancer-8ac10da3-93bd-54c5-a93b-265bc6699689.md)
- Breast carcinoma
- Breast carcinoma by gene expression profile
- [Breast disorder](https://trialight.com/data/condition/breast-disorder-c24c48eb-9ec6-54b1-80b7-1e9cec90eba4.md)
- [Breast neoplasm](https://trialight.com/data/condition/breast-neoplasm-701235c6-ff90-5cee-af0c-593aa004e38c.md)
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md)
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md)
- Estrogen-receptor positive breast cancer
- Her2-receptor negative breast cancer
- Human disease
- Neoplasm
- Neoplasm of thorax
- Neoplastic disease or syndrome
- Progesterone-receptor positive breast cancer
- [Thoracic cancer](https://trialight.com/data/condition/thoracic-cancer-bb0f3b17-0261-5157-830c-759d6c71e62b.md)

### Trials (89)

- A Global Study to Compare the Effects of Fulvestrant and Arimidex in a Subset of Patients With Breast Cancer.
- A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer
- A Phase 1b Study of TAK-700 in Postmenopausal Women With Hormone-receptor Positive Metastatic Breast Cancer
- A Randomized Controlled Trial of Acupuncture for the Management of Hot Flashes in Patients With Hormone Receptor-Positive Breast Cancer
- A Randomized Study Comparing the Immune Modulation Effect of Ribociclib, Palbociclib, and Abemaciclib in ER+/HER2- EBC
- A Safety Study of SGN-LIV1A in Breast Cancer Patients
- A Single Arm Phase II Study of ADjuvant Endocrine Therapy, Pertuzumab, and Trastuzumab for Patients With Anatomic Stage I Hormone Receptor-positive, HER2-positive Breast Cancer
- A Study in Patients With Advanced Breast Cancer
- A Study of Abemaciclib (LY2835219) in Women With HR+, HER2+ Locally Advanced or Metastatic Breast Cancer
- A Study of Abemaciclib and Radiation Therapy in People With Metastatic Breast Cancer
- A Study of Chidamide Plus Endocrine in Maintenance Treatment of HR+/HER2- Breast Cancer After First-line Chemotherapy
- [A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors](https://trialight.com/data/trial/a-study-of-felmetatug-vedotin-sgn-b7h4v-in-advanced-solid-b18fd694-d575-41e6-925e-9ce02c62b3b1.md)
- A Study of Fluvestrant Combined With Oral Vinorelbine in Hormone Receptor-positive Advanced Breast Cancer
- A Study of Revaree Plus in People With Breast Cancer
- A Study of Sirolimus (Albumin-Bound) in Combination With Palbociclib and Fulvestrant for the Treatment of Advanced Breast Cancer
- A Study of TQB3616 Capsules Combined With Fulvestrant Injection in Subjects With Advanced Breast Cancer
- A Study to Assess CLBR001+ABBV-461 in Subjects With Locally Advanced or Metastatic Breast Cancer
- A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors
- Anastrazole, Fulvestrant & Abemaciclib for HR+HER2- Metastatic Breast Cancer
- ARX788 for Treating Patients With HER2-low Locally Advanced Unresectable or Metastatic Breast Cancer

---

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