Hidradenitis suppurativa
Therapeutic area
Dermatology
Rare disease
Yes
- Definition
- A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Hidradenitis suppurativa
- Therapeutic area
- Dermatology
- hidradenitis suppurativa
- acne inversa
- ectopic acne
- fox den disease
- hidradenitis suppurativa
- pyoderma fistulans significa
- verneuil disease
- acne inversa, familial
- Disease mechanisms
- Inflammatory
- All therapeutic areas
- Dermatology
- Severity
- Severe
- MONDO ID
- MONDO:0006559
- Parent condition
- MONDO:0002260
Related records
Broader conditions (10)
- Apocrine sweat gland disorder
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Hidradenitis
- Human disease
- Inflammatory disease
- Integumentary system disorder
- Skin disorder
- Sweat gland disorder
Narrower conditions (4)
- Acne inversa, familial, 1
- Acne inversa, familial, 2
- Acne inversa, familial, 3
- Familial acne inversa
Trials (274)
- 15% TOPICAL RESORCINOL FOR HURLEY I-II HIDRADENITIS SUPPURATIVA.
- 1726-nm Laser for Acne Inversa (Hidradenitis Suppurativa)
- A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
- A 24-Week Real-World Study of Upadacitinib in Moderate-to-Severe Hidradenitis Suppurativa
- A Bioelectric Dressing for Post De-Roofing Treatment of HS
- A Clinical Study With Adalimumab Biosimilar
- A Double-blind Placebo-controlled Randomized Trial Evaluating the Efficacy and Safety of a Novel HSP90 Inhibitor (RGRN-305) in the Treatment of Moderate to Severe Hidradenitis Supppurativa.
- A Global Study Comparing Risankizumab to Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
- A Journey Into Participation Patterns Among Patients With Hidradenitis Suppurativa
- A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic
- A Longitudinal Observational Study of Patients Undergoing Therapy for IMISC
- A National Registry For Patients With Hidradenitis Suppurativa
- A Phase 2 Study to Evaluate the Efficacy and Safety of SAR444656 Compared With Placebo in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa
- A Phase 3 Study to Assess Efficacy Safety and Tolerability of Remibrutinib in Adult and Adolescent Patients With Moderate to Severe Hidradenitis Suppurativa (RECHARGE 1)
- A Phase I Study of QLS12010 Capsules: Safety, Tolerability, PK, PD, and Food Effects in Healthy Adults and Moderate to Severe Atopic Dermatitis Patients
- A Pilot Study to Explore the Role of Gut Flora in Acne
- A Placebo-Controlled Study of the Safety of INCB054707 in Participants With Hidradenitis Suppurativa
- A Proof of Concept Study to Evaluate the Effectiveness of Ustekinumab in Hidradenitis Suppurativa
- A Proof-of-Concept Study of LAD328 in Adults With Hidradenitis Suppurativa
Approved drugs (1)
Drugs in development (59)
- Anakinra Phase 2
- Anifrolumab Phase 2
- Anumigilimab Phase 1
- Apremilast Phase 2
- Avacopan Phase 2
- Bermekimab Phase 2
- Bimekizumab Phase 3
- Brensocatib Phase 2
- Brepocitinib Phase 2
- Brivekimig Phase 2
- Brodalumab Phase 2
- Cannabinol Phase 2
- Ceftriaxone sodium Phase 3
- CJM-112 Phase 2
- Deucravacitinib Phase 2
- Drospirenone Phase 2
- Efalizumab Phase 1
- Eltrekibart Phase 2
- Etanercept Phase 2
- Ethinyl estradiol Phase 2
Other linked drugs (7)
- Clindamycin
- Ertapenem
- Mesalamine
- Rifampin
- Rimabotulinumtoxinb
- Tirzepatide
- Tofacitinib