Herpes simplex infectious disease
Therapeutic area
Infectious Disease
Rare disease
No
- Definition
- A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- No
- Listing at source
- Listed
- Condition name
- Herpes simplex infectious disease
- Therapeutic area
- Infectious Disease
- herpes simplex infectious disease
- Simplexvirus caused disease or disorder
- Simplexvirus disease or disorder
- Simplexvirus infectious disease
- Disease mechanisms
- Acquired
- All therapeutic areas
- Infectious Disease
- Severity
- Moderate
- MONDO ID
- MONDO:0004609
- Parent condition
- MONDO:0005794
Related records
Broader conditions (8)
- Disease
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Herpesviridae infectious disease
- Human disease
- Infectious disease
- Primary viral infectious disease
- Viral infectious disease
Narrower conditions (16)
- Congenital herpes simplex virus infection
- Endotheliitis
- Genital herpes
- Genital herpes simplex type 1 infectious disorder
- Genital herpes simplex type 2 infectious disorder
- Herpes labialis
- Herpes simplex dermatitis
- Herpes simplex encephalitis
- Herpes simplex type 1 infectious disease
- Herpes simplex type 2 infectious disease
- Herpes simplex virus gingivostomatitis
- Herpes simplex virus keratitis
- Herpetic whitlow
- Lip herpes simplex type 1 infectious disorder
- Lip herpes simplex type 2 infectious disorder
- Stromal keratitis
Trials (162)
- 30-Day Trial of Oral Valtrex or Valtrex Plus Aspirin on Shedding of HSV DNA in Tears and Saliva of Volunteers
- 300 Antibody Diagnostic Test Kit
- A Clinical Research Study For The Suppression And Treatment Of Genital Herpes Infection In HIV-Infected Persons
- A Comparative Trial of Valacyclovir Hydrochloride ( 256U87 ) and Acyclovir for the Suppression of Anogenital Herpes Infections in HIV-Infected Patients
- A Phase I Clinical Trial of Recombinant Herpes Zoster Vaccine (CHO Cell)
- A Phase I/II Study of the Safety and Efficacy of Topical 1-(S)-(3-Hydroxy-2-Phosphonylmethoxypropyl)Cytosine Dihydrate (Cidofovir; HPMPC) in the Treatment of Refractory Mucocutaneous Herpes Simplex Disease in Patients With AIDS
- A Pilot Trial of Herpesvirus Treatment in Idiopathic Pulmonary Fibrosis (IPF)
- A Randomized Controlled Trial of Acyclovir Among HIV and HSV-2 Co-Infected Women, Chiang Rai, Thailand
- A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes Labialis
- A Retrospective and Prospective Natural History Study of Patients With WHIM Syndrome
- A Retrospective Chart Review Study of Gene-Eden-VIR/Novirin
- A Safety and Dose-Determining Study of CMX001 In Infants With Neonatal Herpes Simplex Virus (HSV) Infection Involving the Central Nervous System (CNS Disease)
- A Safety And Tolerability Study Of Valaciclovir Oral Suspension In Infants And Children
- A Study of HSV Testing Among Pregnant Women
- A Study of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients
- A Study of Valacyclovir as Treatment for Genital Herpes Simplex Virus in HIV-Infected Patients
- A Study of Valacyclovir to Suppress HSV and HIV Shedding in Coinfected Persons
- A Study on the Reactogenicity, Safety and Immune Response of a Targeted Immunotherapy Against HSV in Healthy Japanese Participants Aged 18-40 Years
- A Study on the Reactogenicity, Safety and Immune Response of a Vaccine Against Herpes Simplex Virus (HSV)-2 in Healthy Participants Aged 18-40 Years
- A Study on the Reactogenicity, Safety, Immune Response, and Efficacy of a Targeted Immunotherapy Against HSV in Healthy Participants Aged 18-40 Years or in Participants Aged 18-60 Years With Recurrent Genital Herpes
Approved drugs (4)
- Acyclovir
- Dexamethasone
- Dexamethasone sodium phosphate
- Trifluridine
Drugs in development (17)
- Acyclovir sodium Phase 3
- Amenamevir Phase 3
- Aspirin Phase 1
- Cidofovir Phase 1
- Docosanol Phase 2
- Edetic acid Phase 2
- Famciclovir Phase 3
- Fialuridine Phase 2
- Foscarnet sodium Phase 3
- Glutamine Phase 2
- Glycine Phase 2
- Pritelivir Phase 1
- Pritelivir mesylate Phase 1
- QS-21 Phase 2
- Valacyclovir Phase 3
- Valacyclovir hydrochloride Phase 3
- Vidarabine Phase 3
Other linked drugs (1)
- Hydrocortisone