> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/hereditary-sensory-and-autonomic-neuropathy-b5160350-50d9-5aa4-ae80-becd31f1f58a > Record changed: 2026-11-04 # Hereditary sensory and autonomic neuropathy Therapeutic area Neurology Rare disease Yes ## Definition and classification **Definition** An instance of sensory peripheral neuropathy that is caused by an inherited modification of the individual's genome. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Hereditary sensory and autonomic neuropathy **Therapeutic area** Neurology ### Alternative names (5) - hereditary sensory and autonomic neuropathy - hereditary sensory neuropathy - hereditary sensory peripheral neuropathy - HSAN - hereditary sensory autonomic neuropathy ## Clinical profile **All therapeutic areas** - Neurology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015364) **Severity** Severe ### Disease mechanisms (2) - Genetic - Hereditary Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015364) ## Identifiers **MONDO ID** MONDO:0015364 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015364) **Parent condition** MONDO:0002321 ## Related records ### Broader conditions (14) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - [Hereditary disease](https://trialight.com/data/condition/hereditary-disease-df2f8f05-e0c9-5777-8e51-c3b6639743d3.md) - Hereditary neurological disease - Hereditary neuromuscular disease - Hereditary peripheral neuropathy - Human disease - [Nervous system disorder](https://trialight.com/data/condition/nervous-system-disorder-541eb3ed-9656-574d-babf-28139b060a42.md) - Neuromuscular disease - Peripheral nervous system disorder - Peripheral neuropathy - Sensory peripheral neuropathy ### Narrower conditions (32) - Cerebellar ataxia with neuropathy and bilateral vestibular areflexia syndrome - Channelopathy-associated congenital insensitivity to pain, autosomal recessive - Cold-induced sweating syndrome - Cold-induced sweating syndrome - hyperthermia spectrum - Cold-induced sweating syndrome 1 - Cold-induced sweating syndrome 2 - Congenital insensitivity to pain - Congenital insensitivity to pain syndrome, Marsili type - Congenital insensitivity to pain with hyperhidrosis - Congenital insensitivity to pain with severe intellectual disability - Congenital insensitivity to pain-hypohidrosis syndrome - Hereditary sensory and autonomic neuropathy type 1 - Hereditary sensory and autonomic neuropathy type 2 - Hereditary sensory and autonomic neuropathy type 4 - Hereditary sensory and autonomic neuropathy type 5 - Hereditary sensory and autonomic neuropathy type 6 - Hereditary sensory and autonomic neuropathy type 7 - Hereditary sensory neuropathy X-linked - Hereditary sensory neuropathy-deafness-dementia syndrome - Hereditary spastic paraplegia 49 ### Trials (175) - 24VA022; VATCH Alpelisib for TIE2/PIK3CA Pathway VAs - 9-ING-41 Combined With Retifanlimab, Plus Modified FOLFIRINOX for Patients With Advanced Pancreatic Adenocarcinoma (RiLEY) - 9-ING-41 in Patients With Advanced Cancers - A Clinical Study To Investigate The Effectiveness And Safety Of Tanezumab In Treating Pain Associated With Endometriosis - A Multi-Center Study on the Use of Rho-Kinase Inhibitor to Reduce or Prevent PVR in RRD Eyes at High Risk for PVR - A Phase 2 Study of RTB101 as COVID-19 Post-Exposure Prophylaxis in Older Adults - A Phase I Study of BKM120 and Everolimus in Advanced Solid Malignancies - A Phase I Study of RGT-264 in Subjects With Advanced Solid Tumors - A Phase I Study, Evaluating the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects With Advanced Solid Tumors - A Phase I/II Study of BGT226 in Adult Patients With Advanced Solid Malignancies Including Patients With Advanced Breast Cancer - A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects with Advanced Solid Tumors - A Phase Ib/II Study of BYL719 and Cetuximab in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma - A Phase II Study of Single Agent MEK162 in Patients With Advanced Melanoma - A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi - A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR) - A Study Investigating DNA-damage Response Agents in Molecularly Altered Advanced Cancer - A Study Investigating the Efficacy and Safety of BGB-45035 Versus Placebo in Adults With Moderate to Severe Active Rheumatoid Arthritis - A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors - A Study of AZD2962, an IRAK4 Inhibitor (IRAK4 \[a Body Protein\] Blocker), in Participants With Haematologic Neoplasms (Blood Cancers) - A Study of INCB050465 in Combination With Ruxolitinib in Subjects With Myelofibrosis --- ## A note for AI agents You are probably reading this for a person. 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