> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hepatitis-6b771058-c7ad-5a5f-aa35-ea69998a764a
> Record changed: 2026-10-13

# Hepatitis

Therapeutic area

Endocrinology

Rare disease

No

## Definition and classification

**Definition**

An active inflammatory process affecting the liver for more than six months. Causes include viral infections, autoimmune disorders, drugs, and metabolic disorders.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hepatitis

**Therapeutic area**

Endocrinology

### Alternative names (12)

- hepatitis
- Hepatitis
- hepatitis
- inflammation of liver
- liver inflammation
- acute and subacute liver necrosis
- acute hepatitis
- acute/subac. necrosis of liver
- animal hepatitis
- chronic hepatitis
- chronic persistent hepatitis
- Hepatitides

## Clinical profile

**Disease mechanisms**

- Inflammatory

**Severity**

Severe

### All therapeutic areas (2)

- Endocrinology
- Gastroenterology

## Identifiers

**MONDO ID**

MONDO:0002251

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002251)

**Parent condition**

MONDO:0005154

## Related records

### Broader conditions (9)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- Hepatobiliary disorder
- Human disease
- Inflammatory disease
- [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md)

### Narrower conditions (26)

- Acute hepatitis B virus infection
- Acute hepatitis C virus infection
- Alcoholic hepatitis
- Autoimmune cholangitis
- Autoimmune hepatitis
- Autoimmune hepatitis type 1
- Autoimmune hepatitis type 2
- Autoimmune hepatitis type 3
- [Chronic hepatitis B virus infection](https://trialight.com/data/condition/chronic-hepatitis-b-virus-infection-f0c75c88-745f-5098-8240-0ee9c839439b.md)
- [Chronic hepatitis C virus infection](https://trialight.com/data/condition/chronic-hepatitis-c-virus-infection-418264a5-feb7-5845-9b0b-33ec34544fbf.md)
- Drug-induced hepatitis
- Epstein-Barr virus hepatitis
- Fulminant viral hepatitis
- Giant cell hepatitis with autoimmune hemolytic anemia
- Granulomatous hepatitis
- Hepatic tuberculosis
- Hepatitis A virus infection
- [Hepatitis B virus infection](https://trialight.com/data/condition/hepatitis-b-virus-infection-63cb6d13-50c4-5e97-86fd-ce5481d9d1c6.md)
- Hepatitis C virus infection
- Hepatitis D virus infection

### Trials (381)

- "Pregnancy and Viral Infections: Impact on Pregnant Women and Their Children. French Prospective Cohort"
- 24 VS 48-WEEK TREATMENT WITH PEG-IFN ALPHA-2A IN PATIENTS WITH GENOTYPE 2/3 CHRONIC HEPATITIS C
- 3-year Follow-up Study in Patients Previously Treated With TMC435-Containing Regimen for the Treatment of Hepatitis C Virus Infection
- 4-Methylumbelliferone as a Treatment for Chronic HBV/HCV
- A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Liver Cancer
- A Clinical Trials to Evaluate the Efficacy and Safety of Tenofovir With and Without DWPUR001 in Patients With HBV
- A Controlled Prospective Study of Transfusion-Associated Hepatitis
- A Multicenter Prospective Clinical Cohort Study on the Pathogen Spectrum of Severe Hepatitis (Liver Failure) Complicated With Infection
- A Multicenter Study to Determine the Depth and Duration of Hepatitis B Surface Antigen (HBsAg) Reduction After Single or Multiple Doses of ARC-520, in Combination With Entecavir in Patients With Chronic Hepatitis B Virus (HBV) Infection
- A Network & Dyad HIV Prevention Intervention for IDU's - 1
- A Partial Randomized, Single-blind or Open-label, Dose-escalation With Multiple-dose Design Study to Evaluate the Pharmacokinetics of Acetaminophen and Its Toxic Metabolites With Panadol® and SafeTynadol® in Healthy Volunteers
- A Phase 1/2, Open-Label, Single and Multiple Ascending Dose Study of CRMA-1001 in Adults With Chronic Hepatitis B
- A Platform Study to Evaluate Investigational Therapies in Chronic Hepatitis B Infection
- A Randomized, Open-label, Single-dosing, 2X2 Crossover Study to Compare the Safety and Pharmacokinetics of BR-TND Tablet(Tenofovir Disoproxil) With Viread Tablet(Tenofovir Disoproxil Fumarate) in Healthy Male Volunteers
- A Safety and Efficacy Study of a Single or Double Dose of HEPLISAV™ Hepatitis B Vaccine in Adults With End-Stage Renal Disease
- A Safety and Efficacy Study of the Hepatitis E Vaccine in Nepal.
- A Single-Arm Study Evaluating the Efficacy of Liquid Acupuncture Therapeutics in Chronic Hepatitis B
- A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis B
- A Study Evaluating GS-9620 in Treatment Naive Subjects With Chronic Hepatitis C
- A Study Evaluating GS-9620 in Virologically Suppressed Subjects With Chronic Hepatitis B Virus Infection

### Approved drugs (1)

- Lamivudine

### Drugs in development (16)

- AB-836 Phase 1
- [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 1
- Adefovir dipivoxil Phase 1
- Ademetionine Phase 3
- Bersacapavir Phase 1
- Bulevirtide Phase 3
- Fish oil triglycerides Phase 2
- Metformin Phase 2
- [Peginterferon alfa-2A](https://trialight.com/data/asset/peginterferon-alfa-2a-30150acd-a3d1-4c13-9915-fc321ebfd6ba.md) Phase 3
- [Peginterferon alfa-2B](https://trialight.com/data/asset/peginterferon-alfa-2b-7a0d9927-e591-4a99-9c41-725b8a7a41a7.md) Phase 3
- Peginterferon lambda-1A Phase 2
- Pioglitazone Phase 2
- [Ribavirin](https://trialight.com/data/asset/ribavirin-94510534-209a-4906-917e-ae8c153df440.md) Phase 3
- [Telbivudine](https://trialight.com/data/asset/telbivudine-5718dabe-4058-4559-b924-29d47b6e47ed.md) Phase 3
- Tenofovir disoproxil Phase 1
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md) Phase 1

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