> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hematopoietic-and-lymphoid-cell-neoplasm-ed3616fa-22fe-5984-94b4-745416e01ef9
> Record changed: 2026-10-13

# Hematopoietic and lymphoid cell neoplasm

Therapeutic area

Hematology

Rare disease

No

## Definition and classification

**Definition**

A neoplasm arising from hematopoietic cells found in the bone marrow, peripheral blood, lymph nodes and spleen (organs of the hematopoietic system). Hematopoietic cell neoplasms can also involve other anatomic sites (e.g. central nervous system, gastrointestinal tract), either by metastasis, direct tumor infiltration, or neoplastic transformation of extranodal lymphoid tissues. The commonest forms are the various types of leukemia, Hodgkin and non-Hodgkin lymphomas, myeloproliferative neoplasms, and myelodysplastic syndromes.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hematopoietic and lymphoid cell neoplasm

**Therapeutic area**

Hematology

### Alternative names (28)

- hematopoietic and lymphoid cell neoplasm
- HEMOLYMPHORETICULAR tumor, malignant
- haematological neoplasm
- haematological tumour
- haematopoietic and lymphoid neoplasms
- haematopoietic cancer
- haematopoietic cell tumour
- haematopoietic malignancy, NOS
- haematopoietic neoplasm
- haematopoietic neoplasms including lymphomas
- haematopoietic tumour
- hematologic cancer
- hematologic malignancy
- hematologic neoplasm
- hematological neoplasm
- hematological tumor
- hematopoietic and lymphoid cell neoplasm
- hematopoietic and lymphoid neoplasms
- hematopoietic cancer
- hematopoietic cell tumor
- hematopoietic malignancy, NOS
- hematopoietic neoplasm
- hematopoietic neoplasms including lymphomas
- hematopoietic tumor
- hematopoietic, Including myeloma

And 3 more, listed on the interactive page.

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Hematology
- Oncology

## Identifiers

**MONDO ID**

MONDO:0044881

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0044881)

**Parent condition**

MONDO:0002334

## Related records

### Broader conditions (9)

- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Hematologic disorder
- [Hematopoietic and lymphoid system neoplasm](https://trialight.com/data/condition/hematopoietic-and-lymphoid-system-neoplasm-510101ac-7ce5-5dd1-8980-f2f110effdf0.md)
- Human disease
- Neoplasm
- Neoplastic disease or syndrome

### Narrower conditions (494)

- A53 diffuse large B-cell lymphoma
- [Acquired polycythemia vera](https://trialight.com/data/condition/acquired-polycythemia-vera-5c3132a8-49a0-5b93-b3d6-cd5f1fa9e10e.md)
- Acute basophilic leukemia
- Acute biphenotypic leukemia
- Acute erythroid leukemia
- [Acute leukemia](https://trialight.com/data/condition/acute-leukemia-29973a51-6824-5634-b887-713630819eb2.md)
- Acute leukemia of ambiguous lineage
- Acute lymphoblastic leukemia
- Acute mast cell leukemia
- Acute megakaryoblastic leukemia
- Acute megakaryoblastic leukemia in adult
- Acute megakaryoblastic leukemia in down syndrome
- Acute megakaryoblastic leukemia without down syndrome
- Acute monocytic leukemia
- Acute myeloblastic leukemia with maturation
- Acute myeloblastic leukemia without maturation
- [Acute myeloid leukemia](https://trialight.com/data/condition/acute-myeloid-leukemia-b0971a7a-c18d-544e-bd7f-b1a13b9caa30.md)
- Acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent
- Acute myeloid leukemia and myelodysplastic syndromes related to radiation
- Acute myeloid leukemia and myelodysplastic syndromes related to topoisomerase type 2 inhibitor

### Trials (228)

- 2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological Malignancies
- 211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
- 64Cu-DOTA-pembrolizumab PET for the Study of PD1 Expression
- A Mobile Application, Oncpatient, to Assist Patients Undergoing Radiation Therapy
- A Multidisciplinary Approach to Improve the Health of Older Adults With Blood Cancers After Stem Cell Transplantation
- A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients
- A Two Step Approach to Allogeneic Hematopoietic Stem Cell Transplantation for Patients With Hematologic Malignancies-Increasing GVT Effects Without Increasing Toxicity
- Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease
- Addition of Cord Blood Tissue-Derived Mesenchymal Stromal Cells to Ruxolitinib for the Treatment of Steroid-Refractory Acute Graft Versus Host Disease
- Adoption of Audio Recording in the Outpatient Supportive Care Center
- ADVANCE: An Observational Study To Determine Bortezomib Safety and Effectiveness at First Relapse After Participation In First Line HOVON-49/50 Clinical Studies.
- Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
- An Educational Intervention on Provider Knowledge for the Support of Cancer Survivors
- An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study
- Anakinra for the Reduction of CAR-T Toxicity in Patients With Relapsed or Refractory Large B-cell Lymphoma
- Analyse of Tumour and Constitutional DNA for the Study of the Determinism in Child Neoplasia
- Apixaban in Preventing Secondary Cancer Related Venous Thrombosis in Cancer Patients Who Have Completed Anticoagulation Therapy
- Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit
- Atezolizumab in Treating Patients With Cancer Following Adoptive Cell Transfer
- Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies

### Drugs in development (91)

- Acalabrutinib Phase 2
- Aderbasib Phase 1
- Aldesleukin Phase 1
- Alemtuzumab Phase 2
- [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md) Early phase 1
- Alvelestat Phase 1
- [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 2
- [Azacitidine](https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f.md) Phase 2
- Bendamustine hydrochloride Phase 1
- [Bortezomib](https://trialight.com/data/asset/bortezomib-35a853cf-26ab-4a4c-a405-ae671d364aad.md) Phase 2
- Busulfan Phase 2
- Cefepime Phase 2
- [Cholecalciferol](https://trialight.com/data/asset/cholecalciferol-c9dc6a9a-8bc7-4070-a34e-535013073648.md) Phase 2
- Cilastatin Phase 2
- Crisantaspase Phase 2
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3
- Cyclosporine Phase 2
- Cytarabine Phase 2
- Daptomycin Phase 2
- [Daunorubicin](https://trialight.com/data/asset/daunorubicin-903e3e75-4637-461c-9ca8-608fdf707576.md) Phase 1

### Other linked drugs (7)

- [Abatacept](https://trialight.com/data/asset/abatacept-a318efa4-5922-464c-8f45-90c18515f1c5.md)
- Darbepoetin alfa
- Dorocubicel
- [Gilteritinib](https://trialight.com/data/asset/gilteritinib-68aa5aec-0e4f-4efa-bdc8-eba76c8a8a3a.md)
- [Pegfilgrastim](https://trialight.com/data/asset/pegfilgrastim-1d67f09f-a3d2-4dbc-bfb9-efed1a49c050.md)
- Pentamidine
- Posaconazole

---

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