> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/hand-foot-and-mouth-disease-9d0921d2-bfb0-5f4d-848d-f80dae061a88
> Record changed: 2026-10-13

# Hand, foot and mouth disease

Therapeutic area

Dermatology

Rare disease

No

## Definition and classification

**Definition**

A clinical syndrome that is usually caused by enterovirus infection, and that is characterized by fever, anorexia, and painful sores in the mouth, distal extremities, and/or other sites, including the buttocks.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Hand, foot and mouth disease

**Therapeutic area**

Dermatology

### Alternative names (4)

- hand, foot and mouth disease
- HFMD
- hand foot and mouth disease
- hand, foot, and mouth disease

## Clinical profile

**Disease mechanisms**

- Acquired

**Severity**

Mild

### All therapeutic areas (2)

- Dermatology
- Infectious Disease

## Identifiers

**MONDO ID**

MONDO:0005779

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005779)

**Parent condition**

MONDO:0005721

## Related records

### Broader conditions (14)

- Coxsackievirus infectious disease
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- Enterovirus infectious disease
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Integumentary system disorder
- Picornaviridae infectious disease
- Primary viral infectious disease
- [Skin disorder](https://trialight.com/data/condition/skin-disorder-c8e27943-0efd-5c2b-abce-01c2ef37e853.md)
- [Skin disorder caused by infection](https://trialight.com/data/condition/skin-disorder-caused-by-infection-023b0ddd-a4ce-5055-b56a-58eced90502b.md)
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md)

### Trials (60)

- A Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants
- A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children
- A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Aged 6-35 Months
- A Clinical Trial To Evaluate Reduning Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
- A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
- A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease
- A Follow-up Study for a Phase III, Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine
- A Multi-Center Clinical Trial To Evaluate Chinese Herbal Medicines in the Treatment of Severe Hand-foot-mouth Disease
- A Phase II, Safety and Efficacy Study of Inactivated EV 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants
- A Protected Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants and Children
- A Safety Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Adults, Children and Infants
- A Serosurvey Study of Hand, Foot, and Mouth Disease in Indonesia
- A Study to Evaluate the Efficacy, Immunogenicity and Safety of an EV71 Vaccine in Healthy Infants and Children
- A Study to Evaluate the Immunogenicity and Safety of EV71 Vaccine in Pediatric Subjects
- A Study to Evaluate the Safety and Immunogenicity of EV71 Vaccine in Pediatric Subjects Aged 3 to 6 Years and 6 to 35 Months Old
- Active Case Finding of Clinical Hand Foot Mouth Disease in Children Aged 6 Months Old to 18 Years Old in Indonesia
- An Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine
- An Immunity Persistence Study of Enterovirus 71 Inactivated Vaccine (Vero Cell)
- Artificial Intelligence-driven Virtual Standardized Pediatric Patients Trial
- Bridging Clinical Trial of EV71 Vaccine in Vietnamese Children

### Drugs in development (2)

- Magnesium sulfate Phase 2
- Suramin hexasodium Phase 1

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