> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/gram-negative-bacterial-infections-74f26084-eb3d-5211-8b61-2deac319f501 > Record changed: 2026-10-13 # Gram-negative bacterial infections Therapeutic area Infectious Disease Rare disease No ## Definition and classification **Definition** Infections caused by bacteria that show up as pink (negative) when treated by the gram-staining method. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Gram-negative bacterial infections **Therapeutic area** Infectious Disease ### Alternative names (12) - gram-negative bacterial infections - bacterial infection, gram-negative - bacterial infections, gram negative - bacterial infections, gram-negative - bacterial infections, gramme negative - gram negative bacterial infections - gram-negative bacterial infection - gramme negative bacterial infections - infection, gram-negative bacterial - infections, gram negative bacterial - infections, gram-negative bacterial - infections, gramme negative bacterial ## Clinical profile **Disease mechanisms** - Acquired **All therapeutic areas** - Infectious Disease **Severity** Unknown ## Identifiers **MONDO ID** MONDO:0021678 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021678) **Parent condition** MONDO:0005113 ## Related records ### Broader conditions (6) - [Bacterial infectious disease](https://trialight.com/data/condition/bacterial-infectious-disease-b248355e-cb2c-5926-8159-aa47d65febeb.md) - Disease - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) ### Narrower conditions (94) - Acinetobacter infectious disease - African tick-bite fever - Anaplasmataceae infectious disease - Astrakhan spotted fever - Asymptomatic neurosyphilis - Bacillary angiomatosis - Bacterial meningitis caused by gram-negative bacteria - Bacteroidaceae infectious disease - Bacteroides infectious disease - Bartonellaceae infectious disease - Bartonellosis - Bejel - Bordetella parapertussis infectious disease - Bordetellosis - Boutonneuse fever - Brill-Zinsser disease - Burkholderia infectious disease - Cardiovascular syphilis - Cat-scratch disease - Cepacia syndrome ### Trials (53) - A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult - A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Minocin® (Minocycline) for Infections Caused by Gram-negative Bacteria in a Real World Setting - A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants - A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants - A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants - [A Study to Evaluate Safety and Efficacy of TP-05 in Healthy Participants With Tick Exposure](https://trialight.com/data/trial/a-study-to-evaluate-safety-and-efficacy-of-tp-05-in-healthy-36bbc9a7-af6b-4fa7-8a63-3fa6390bb569.md) - A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Ascending Intravenous Single Dose and Repeat Dose of GSK3342830 - A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants - A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH) - An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT - Benefit of Clarithromycin in Patients With Severe Infections Through Modulation of the Immune System - Burden of Antibiotic Resistance in Gram-Negative Infections in Dutch Hospitals - Ceftazidime-Avibactam PK/PD and Resistance in Hematology Patients - Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation - Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV - Comparison of Solid Organ Transplant - Consistency & Immunogenicity Study of 3 Lots of GSK's Hib Conjugate Vaccine Versus ActHIB & Pentacel in Healthy Infants - Different Administration Regimens of CAZ-AVI in Combination With ATM for the Treatment of CR-GNB - Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis - Early-Onset Sepsis Surveillance Study ### Approved drugs (2) - Cefiderocol sulfate tosylate - Ertapenem sodium ### Drugs in development (10) - Ancremonam Phase 1 - Apramycin Phase 1 - Avibactam Phase 2 - Aztreonam Phase 2 - Cefiderocol Phase 2 - [Meropenem](https://trialight.com/data/asset/meropenem-a90880e5-37b0-473b-bf12-d5f0de7894c2.md) Phase 1 - Nacubactam Phase 1 - Tigecycline Phase 3 - Xeruborbactam Phase 1 - Xeruborbactam sodium Phase 1 ### Other linked drugs (5) - Ceftazidime - Cilastatin - [Imipenem](https://trialight.com/data/asset/imipenem-f7af1694-45a9-4315-b812-d17767d1ad0f.md) - [Minocycline](https://trialight.com/data/asset/minocycline-0789feeb-1396-4fb9-bfd9-d51fefbb5e59.md) - Relebactam --- ## A note for AI agents You are probably reading this for a person. 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