> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/glaucoma-7a3c05c0-9871-55db-af74-962761181784 > Record changed: 2026-10-13 # Glaucoma Therapeutic area Ophthalmology Rare disease No ## Definition and classification **Definition** Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Glaucoma **Therapeutic area** Ophthalmology ### Alternative names (3) - glaucoma - glaucoma - glaucoma (disease) ## Clinical profile **All therapeutic areas** - Ophthalmology **Severity** Moderate ## Identifiers **MONDO ID** MONDO:0005041 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005041) **Parent condition** MONDO:0005328 ## Related records ### Broader conditions (6) - Disease - Disease by body system or component - Disorder of orbital region - Disorder of visual system - Eye disorder - Human disease ### Narrower conditions (50) - Acute closed-angle glaucoma - Anatomical narrow angle borderline glaucoma - Angle-closure glaucoma - Anterior segment dysgenesis 3 - Anterior segment dysgenesis 6 - Aqueous misdirection - Borderline glaucoma - Chronic closed-angle glaucoma - Congenital glaucoma - CYP1B1-related glaucoma with or without anterior segment dysgenesis - Exfoliation syndrome - Glaucoma 1, open angle, A - Glaucoma 1, open angle, J - Glaucoma 1, open angle, K - Glaucoma 1, open angle, l - Glaucoma 1, open angle, M - Glaucoma 1, open angle, N - Glaucoma 1, open angle, O - Glaucoma 1, open angle, P - Glaucoma 3, primary congenital, C ### Trials (1,359) - "First-in-human" Study To Assess the Safety and Tolerability of PBF-677 in Healthy Volunteers - "My Eyes, My Light": Amar Chokh, Amar Alo - 1 Year Study Trav/Brinz QD Fixed Combination Versus COSOPT - 12-Month Stability of Diurnal IOP Control on Cosopt - 180 Degree vs. 360 Degree Selective Laser Trabeculoplasty as Initial Therapy for Glaucoma - 24-hour Control of Intraocular Pressure (IOP) in Ocular Hypertension - 24-hour Efficacy and Ocular Surface With Talfuprost and Triple Combined Therapy - 24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration. - 24-hour Intraocular Pressure (IOP) Control With the Bimatoprost/Timolol Fixed Combination - 24-Hour Intraocular Pressure Control With Bimatoprost/Timolol Versus Latanoprost as First Choice - 24-hour Intraocular Pressure Control With Travoprost/Timolol Fixed Combination Versus Travoprost - 24-Hour Intraocular Pressure With Brinzolamide/Timolol Versus Brimonidine/Timolol - 24-hour IOP Fluctuation Profile Recorded With SENSIMED Triggerfish in Primary Open-angle Glaucoma (POAG) Patients After Cataract Surgery - 24-hour IOP-lowering Effect of 0.01% Bimatoprost - 24-hour Wear Performance and Safety Study of Smartlens miLens Contact Lens for IOP Monitoring - 24-hr Intraocular Pressure (IOP) Patterns of Glaucoma Patients After Selective Laser Trabeculoplasty (SLT) - 24-hr Intraocular Pressure Control With Dorzolamide/Timolol vs the Brimonidine/Timolol Fixed Combination - 24-hr Intraocular Pressure Control With SIMBRINZA ® - 24-hr IOP With Travoprost/Timolol Compared With Latanoprost/Timolol in XFG - 5 Years Long Term Results After Standalone CyPass-Implantation ### Approved drugs (37) - Acetazolamide - Acetazolamide sodium - Acetylcholine - Apraclonidine - Betaxolol - [Bimatoprost](https://trialight.com/data/asset/bimatoprost-6eef0f4d-2227-4a51-94e0-7508a5f1c01b.md) - Brimonidine - Brimonidine tartrate - Brinzolamide - Carbachol - Carteolol - Clonidine - Dapiprazole - Demecarium - Dichlorphenamide - Dipivefrin - Dorzolamide - Dorzolamide hydrochloride - Echothiophate - Epinephrine ### Drugs in development (41) - Aceclidine Phase 3 - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Early phase 1 - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) Phase 3 - AMA0076 Phase 2 - Befunolol Phase 2 - Betamethasone Phase 2 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 3 - Bimatoprost grenod Phase 1 - Bosentan Phase 1 - Cannabinol Phase 2 - [Cenegermin](https://trialight.com/data/asset/cenegermin-c47bd113-cac2-4c57-a094-530d311415a9.md) Phase 1 - Ciliary neurotrophic factor Phase 2 - Cyclosporine Phase 2 - Decorin Phase 1 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3 - Ethacrynic acid Phase 1 - Fluocinolone acetonide Early phase 1 - [Fluorouracil](https://trialight.com/data/asset/fluorouracil-f8444d73-5c73-4f35-aa71-67d578277450.md) Phase 3 - [Infliximab](https://trialight.com/data/asset/infliximab-4ac1099c-60c4-4b24-80f5-85ddb5503b21.md) Phase 1 - [Insulin human](https://trialight.com/data/asset/insulin-human-99c024c5-521b-478f-a4e1-d5705d2c66d8.md) Phase 1 ### Other linked drugs (9) - Carteolol hydrochloride - Cholesterol - Colforsin - Dexmedetomidine - Ketorolac - Prednisolone acetate - Ripasudil hydrochloride dihydrate - Rutin - [Triamcinolone](https://trialight.com/data/asset/triamcinolone-c53cf39c-0a06-4666-8b46-0c99745c9c4b.md) --- ## A note for AI agents You are probably reading this for a person. 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