> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/gingivitis-82582680-34f0-54d2-abbe-433510e71aaa
> Record changed: 2026-11-04

# Gingivitis

Therapeutic area

Rheumatology

Rare disease

No

## Definition and classification

**Definition**

A disorder involving inflammation of the gums; may affect surrounding and supporting structures of the teeth.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Gingivitis

**Therapeutic area**

Rheumatology

### Alternative names (8)

- gingivitis
- Dental Plaque and Gingivitis
- gingiva inflammation
- Gingivitis and Periodontal Diseases
- inflammation of gingiva
- Mild Gingivitis
- acute gingivitis
- chronic gingivitis

## Clinical profile

**Disease mechanisms**

- Inflammatory

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002508)

**All therapeutic areas**

- Rheumatology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002508)

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0002508

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002508)

**Parent condition**

MONDO:0002021

## Related records

### Broader conditions (13)

- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Gingival disorder
- Human disease
- Inflammatory disease
- Mouth disorder
- Mouth mucosa disorder
- Mucositis
- [Musculoskeletal system disorder](https://trialight.com/data/condition/musculoskeletal-system-disorder-16f6e157-12a0-54ee-9e24-377731f344a5.md)
- Periodontal disorder
- Skeletal system disorder
- Stomatitis

### Narrower conditions (2)

- Chronic gingivitis
- Necrotizing ulcerative gingivitis

### Trials (635)

- "Safeguard Your Smile" an Oral Health Literacy Intervention Promoting Positive Oral Hygiene Self-care Behavior
- "The Efficacy of Acacia Catechu Mouthrinse as Antiplaque and Antigingivitis Agent in Fixed Orthodontic Appliance Patients.
- "Triphala" - A New Herbal Mouthwash in Gingivitis
- (NOD)-Like Receptors CARD Domain-Containing 4 Levels in Individuals With Periodontitis
- 0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis
- 6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health
- A 8-month Study on the Use of Intra-oral Camera and Text Messages on Gingivitis Control
- A Bleeding-Model Clinical Study
- A Clinical and Imaging Study to Evaluate a Novel Dentifrice
- A Clinical Comparison of an Experimental Power Brush Compared to a Manual Toothbrush
- A Clinical Study Investigating the Effect of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health
- A Clinical Study Investigating the Effects of a Dentifrice Containing 0.454% Stannous Fluoride on Gingivitis Treatment and Plaque Reduction When Used Twice Daily for 12 Weeks
- A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
- A Clinical Study Investigating the Efficacy of a Stannous Fluoride Dentifrice in Improving Gingival Health After Twice Daily Use for 3 Weeks
- A Clinical Study Investigating the Efficacy of an Experimental Toothpaste Containing Stannous Fluoride in Improving Gingival Health
- A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and Gingivitis
- A Clinical Study to Assess the Gingivitis and Plaque Effects of Various Dentifrices
- A Clinical Study to Assess the Gingivitis Effects of Various Dentifrices
- A Clinical Study to Assess the Plaque and Gingivitis Effects of a Stannous Fluoride Dentifrice
- A Clinical Study to Evaluate the Effectiveness of an Experimental Toothpaste in Improving Gum Health and Reducing Plaque Accumulation

### Approved drugs (5)

- Chlorhexidine gluconate
- Hydrogen peroxide
- Sodium fluoride
- [Sodium monofluorophosphate](https://trialight.com/data/asset/sodium-monofluorophosphate-9c35619e-72d7-4153-9ef4-f491755ee3e9.md)
- [Stannous fluoride](https://trialight.com/data/asset/stannous-fluoride-eb49d118-dc3f-4633-a9d1-c037ee5b5c77.md)

### Drugs in development (33)

- Alcohol Phase 1
- ALOE Phase 2
- AMY-101 Phase 1
- Bifidobacterium SPP. Phase 3
- Centella asiatica extract Phase 3
- Cetylpyridinium chloride Phase 1
- Chamomile Phase 3
- [Chlorhexidine](https://trialight.com/data/asset/chlorhexidine-73810300-e838-4872-8cbd-4e84000f38de.md) Phase 3
- Chlorhexidine diacetate Phase 3
- Chlorhexidine hydrochloride Phase 3
- Chlorhexidine phosphanilate Phase 3
- Cholecalciferol Early phase 1
- Curcumin Phase 1
- Ginger Phase 3
- Hyaluronic acid Phase 3
- Iodine Phase 3
- Metronidazole Phase 3
- Metronidazole hydrochloride Phase 3
- Octenidine hydrochloride Phase 2
- Olive oil Phase 2

### Other linked drugs (6)

- Cyproterone acetate
- Delmopinol
- Ethinyl estradiol
- Myrrh
- Sodium carbonate
- Wax, emulsifying

---

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