> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/generalized-anxiety-disorder-06f2f230-65ba-5929-af6a-36d14f38281d > Record changed: 2026-10-13 # Generalized anxiety disorder Therapeutic area Psychiatry Rare disease No ## Definition and classification **Definition** An anxiety disorder characterized by excessive and difficult-to-control worry about a number of life situations. The worry is accompanied by restlessness, fatigue, inability to concentrate, irritability, muscle tension, and/or sleep disturbance and lasts for at least 6 months. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Generalized anxiety disorder **Therapeutic area** Psychiatry ### Alternative names (2) - generalized anxiety disorder - GAD ## Clinical profile **Severity** Mild ### All therapeutic areas (2) - Neurology - Psychiatry ## Identifiers **MONDO ID** MONDO:0001942 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001942) **Parent condition** MONDO:0005618 ## Related records ### Broader conditions (10) - [Anxiety disorder](https://trialight.com/data/condition/anxiety-disorder-d84a28fc-7045-53b8-a1b6-52babcd37d08.md) - [Brain disorder](https://trialight.com/data/condition/brain-disorder-4e393319-afcc-52a0-8ac4-4c73ea743874.md) - [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md) - Disease - Disease by body system or component - Disease by developmental or physiological process - Human disease - [Mental disorder](https://trialight.com/data/condition/mental-disorder-6dfe385f-02c0-52b1-895d-e6ed79c12e5f.md) - Nervous system disorder - Psychiatric disorder ### Trials (513) - 6-Month Open-Label Safety Study Of PD 0332334 In Elderly Patients With Generalized Anxiety Disorder (GAD) - 6-Session Treatment for Generalized Anxiety Disorder - A 10 Week Open-Label Pilot Study to Evaluate the Effectiveness and Safety of Memantine(Namenda) as Augmentation Therapy in Patients With Generalized Anxiety Disorder - A 10-Week Efficacy and Safety Study for of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder - A 10-Week Study Evaluating the Efficacy And Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder - A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 for the Treatment of Generalized Anxiety Disorder (3) - A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (1) - A 10-week Study Evaluating the Efficacy and Safety of PD 0332334 in Patients With Generalized Anxiety Disorder (2) - A 10-Week Study for Efficacy and Safety Study of Gabitril in the Treatment of Adults With Generalized Anxiety Disorder - A 14 Week, Randomized, Placebo-Controlled Cross-Over Study of Methylphenidate Hydrochloride Controlled Release Capsules in Adult ADHD With and Without Anxiety Disorder Comorbidity - A 5-Week Trial Of PD 0332334 And Alprazolam Extended Release Compared To Placebo In Patients With Generalized Anxiety Disorder - A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD) - A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder - A Clinical Trial to Study the Effects of Sensoril® for Patients With Generalized Anxiety Disorder - A Collaborative Care Program to Improve Treatment of Depression and Anxiety Disorders in Cardiac Patients - A Comparison Between Cognitive, Behavioral, and Cognitive-Behavioral Therapy for Generalized Anxiety Disorder - A Dose-Finding Study of MM120 (LSD D-Tartrate) for the Treatment of Anxiety Symptoms - A Dose-Response Safety Study of ENX-102 in Patients With GAD - A Feasibility Study of Group Metacognitive Therapy Versus Mindfulness Meditation Therapy - A Long-Term Study Continuing on From Study 04-001-01 of an Experimental Medication in Adults With Anxiety Disorder ### Approved drugs (5) - Alprazolam - Buspirone hydrochloride - Escitalopram oxalate - [Pregabalin](https://trialight.com/data/asset/pregabalin-c76529d4-1815-46a3-954e-cf21d394857b.md) - Venlafaxine hydrochloride ### Drugs in development (24) - Buspirone Phase 3 - Cariprazine Phase 2 - Chamomile Phase 3 - Cimetidine Phase 1 - Darigabat Phase 2 - Duloxetine Phase 3 - [Escitalopram](https://trialight.com/data/asset/escitalopram-a5f62852-0d12-4a2c-b732-a5f5c96b7727.md) Phase 3 - Eszopiclone Phase 2 - Fluvoxamine Phase 3 - Glutamine Phase 2 - Imagabalin Phase 3 - Metformin Phase 1 - MK-0777 Phase 2 - Ocinaplon Phase 3 - Paroxetine Phase 3 - Pexacerfont Phase 2 - Quetiapine fumarate Phase 3 - Sertraline Phase 3 - Tedatioxetine Phase 1 - Tiagabine hydrochloride Phase 3 ### Other linked drugs (4) - Duloxetine hydrochloride - Fluoxetine - Norepinephrine - Serotonin --- ## A note for AI agents You are probably reading this for a person. 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