> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/fatty-liver-disease-07d6a7b0-d908-57e0-8042-aeb4cd71f7a4
> Record changed: 2026-11-04

# Fatty liver disease

Therapeutic area

Endocrinology

Rare disease

No

## Definition and classification

**Definition**

A reversible condition wherein large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Fatty liver disease

**Therapeutic area**

Endocrinology

### Alternative names (5)

- fatty liver disease
- Atherosclerosis With Diabetes Mellitus and Fatty Liver
- fatty liver
- Fatty Liver , Electroacupuncture, Lipid Profile
- Fatty Liver, Nonalcoholic

## Clinical profile

**Severity**

Mild

### All therapeutic areas (2)

- Endocrinology
- Gastroenterology

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004790)

## Identifiers

**MONDO ID**

MONDO:0004790

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004790)

**Parent condition**

MONDO:0005154

## Related records

### Broader conditions (7)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Disease
- Disease by body system or component
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- Hepatobiliary disorder
- Human disease
- [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md)

### Narrower conditions (6)

- Alcoholic fatty liver disease
- Metabolic dysfunction and alcohol associated liver disease
- [Metabolic dysfunction-associated steatohepatitis](https://trialight.com/data/condition/metabolic-dysfunction-associated-steatohepatitis-05fad825-0fff-55c9-8746-0cb406b65c65.md)
- [Metabolic dysfunction-associated steatotic liver disease](https://trialight.com/data/condition/metabolic-dysfunction-associated-steatotic-liver-disease-beb92cb4-74bc-5e17-96f1-97aeed54ab35.md)
- NAFLD1
- Visceral steatosis, congenital

### Trials (624)

- "Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
- "LiverColor": Machine Learning in Liver Photographs
- 12-Month Once-a-week HIIT Improves Body Adiposity and Liver Fat
- A Bidirectional Study in Exploring the Dynamic Changes of Plasma and Urine Metabolites of Liver Cancer
- A Case Control Study Evaluating the Prevalence of Non-Alcoholic Fatty Liver Disease Among Patients With Psoriasis
- A Clinical Trial of Chazhu Xiaozhi Decoction Against Non-alcoholic Fatty Liver Disease
- A Clinical Trial of Longqi Jiangzhi Decoction Against Non-alcoholic Fatty Liver Disease
- A Clinical Trial to Evaluate the Efficacy and Safety of Two Aramchol Doses Versus Placebo in Patients With NASH
- A Hepatitis B With Hepatic Steatosis Study
- [A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)](https://trialight.com/data/trial/a-master-protocol-of-multiple-agents-in-adults-with-e6b397f9-90a9-42e3-81a6-c73e9176a43c.md)
- A Metabolomics-based Study to Explore the Mechanism of Remission of Metabolic Syndrome Radical Resection of Colorectal Cancer
- A Multiple Ascending Dose Study of Pegozafermin in Participants With Biopsy Confirmed Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) and at High Risk of NASH
- A Nutrigenetic Intervention in MASLD
- A One-Year, Randomized, Double-Blind, Placebo-Controlled Trial of Rosiglitazone in Non-Alcoholic Steatohepatitis
- A Pathophysiological Study of the Postprandial Human Liver (PLS)
- A Phase 1 Single and Multiple-Dose Study of Aramchol in Healthy Male Volunteers
- A Phase 1a/1b Study of CB4211 in Healthy Non-obese Subjects and Subjects With Nonalcoholic Fatty Liver Disease
- A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASH and F2/F3 Fibrosis
- A Phase 3 Study Evaluating the Safety and Efficacy of Denifanstat in Patients With MASLD and MASH
- A Phase II Study of the Effect of a Low Calorie Diet on Patients Undergoing Liver Resection

### Drugs in development (39)

- Acetic acid C-11 Early phase 1
- Amino acids Phase 2
- ASP-9831 Phase 2
- [Cannabidiol](https://trialight.com/data/asset/cannabidiol-e1ac1a9a-1111-460c-8a8f-5216571adce8.md) Phase 2
- Cholic acid Phase 2
- Cilostazol Phase 1
- Cysteamine Phase 1
- D-limonene Early phase 1
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md) Phase 3
- Eplerenone Phase 2
- [Esomeprazole](https://trialight.com/data/asset/esomeprazole-852b606c-0a4e-4827-8fd8-7ca4ee307b02.md) Phase 1
- Exenatide Phase 2
- [FISH OIL](https://trialight.com/data/asset/fish-oil-ad06c0e1-eb05-4af3-8ddc-aeba0adf11fd.md) Phase 2
- Ginger Early phase 1
- Hydroxychloroquine Phase 3
- Icomidocholic acid Phase 2
- Icosapent Phase 2
- Lactobacillus acidophilus Phase 1
- [Levothyroxine](https://trialight.com/data/asset/levothyroxine-ca6d0d6d-70df-4340-bb6f-6328ecdeaf6b.md) Phase 1
- Maraviroc Phase 2

### Other linked drugs (11)

- Canagliflozin
- Choline chloride
- Diacerein
- [Empagliflozin](https://trialight.com/data/asset/empagliflozin-09301932-ac0f-4eb7-8d1d-bd13fdbb6ab8.md)
- [Entecavir](https://trialight.com/data/asset/entecavir-4df4be16-2f66-48e2-810c-24457b3f43fc.md)
- Erdosteine
- Glucagon
- Obeticholic acid
- [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md)
- [Tenofovir alafenamide fumarate](https://trialight.com/data/asset/tenofovir-alafenamide-fumarate-9adf6f5f-c34a-4fdb-9c9f-210ec050ca0b.md)
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md)

---

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