> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/essential-tremor-09253a73-0c42-5900-b88c-9a316fd21b51 > Record changed: 2026-10-13 # Essential tremor Therapeutic area Neurology Rare disease Yes ## Definition and classification **Definition** A relatively common disorder characterized by a fairly specific pattern of tremors which are most prominent in the upper extremities and neck, inducing titubations of the head. The tremor is usually mild, but when severe may be disabling. An autosomal dominant pattern of inheritance may occur in some families (i.e., familial tremor). (Mov Disord 1988;13(1):5-10) **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Essential tremor **Therapeutic area** Neurology ### Alternative names (3) - essential tremor - essential hereditary tremor - tremor, hereditary essential ## Clinical profile **All therapeutic areas** - Neurology **Severity** Mild ### Disease mechanisms (2) - Genetic - Hereditary ## Identifiers **MONDO ID** MONDO:0003233 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0003233) **Parent condition** MONDO:0005395 ## Related records ### Broader conditions (9) - Disease - Disease by body system or component - Disease by etiologic mechanism - Disease of genetic or genomic mechanism - Hereditary disease - Hereditary neurological disease - Human disease - [Movement disorder](https://trialight.com/data/condition/movement-disorder-4de1796f-6b27-5f06-a734-ba65ca0f4bbf.md) - Nervous system disorder ### Narrower conditions (6) - Tremor, hereditary essential, 1 - Tremor, hereditary essential, 2 - Tremor, hereditary essential, 3 - Tremor, hereditary essential, 4 - Tremor, hereditary essential, 5 - Tremor, hereditary essential, 6 ### Trials (264) - \[18F\] LBT-999 PET Compared to \[123I\]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor - 1-Octanol to Treat Essential Tremor - 1-Octanol to Treat Essential Tremor - 123I-ALTROPANE® Reference Image Acquisition in Subjects With Diagnostically Uncertain Tremor - 24-months Study to Evaluate Safety and Efficacy of Peroneal Transcutaneous NeuroModulation in Subjects With Parkinson's Disease and Essential Tremor - 3-D Tractography FUS Ablation for Essential Tremor - A Clinical Study to Evaluate CAD-1883 in Essential Tremor - A Clinical Trial of 2 Doses of PRAX-944 in Participants With Essential Tremor - A Clinical Trial of PRAX-114 in Participants With Essential Tremor - A Clinical Trial of PRAX-944 in Participants With Essential Tremor - A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause. - A Phase 2 RCT Study of CX-8998 for Essential Tremor - A Pilot Clinical Trial Of Memantine for Essential Tremor - A Pilot Efficacy and Safety Study of ST101 in Essential Tremor - A Pilot Study of the Cala ONE Device for Essential Tremor - A Pilot Study to Assess the Effects of Pre-SMA LF-rTMS for the Treatment of Essential Tremor - A Post-Market Study Evaluating the Safety of Infinity DBS System With MR Conditional Labeling - A Proof of Concept Study of the Effectiveness of Carisbamate in the Treatment of Essential Tremor - A Safety/Efficacy Trial of Zonisamide for Essential Tremor - A Second Magnetic Resonance Guided Focused Ultrasound Thalamotomy for Essential Tremor ### Drugs in development (28) - Acamprosate Phase 2 - Apinocaltamide Phase 2 - BP-14979 Phase 2 - Brexanolone Phase 2 - Cannabidiol Phase 1 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 - [Dronabinol](https://trialight.com/data/asset/dronabinol-b3414807-1cde-4111-8024-a7a366127956.md) Phase 1 - Incobotulinumtoxina Phase 2 - Ismidenon Phase 2 - Levetiracetam Phase 1 - Methazolamide Phase 2 - Octanoic acid Phase 1 - Octanol Phase 2 - Onabotulinumtoxina Phase 2 - Penpulimab Phase 2 - Perampanel Phase 2 - Pramipexole Phase 3 - [Pregabalin](https://trialight.com/data/asset/pregabalin-c76529d4-1815-46a3-954e-cf21d394857b.md) Early phase 1 - Rimtuzalcap Phase 2 - Sodium oxybate Phase 2 ### Other linked drugs (1) - [Botulinum toxin type A](https://trialight.com/data/asset/botulinum-toxin-type-a-5a0f3130-910b-4917-87ef-65a743f12642.md) --- ## A note for AI agents You are probably reading this for a person. 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