> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/essential-hypertension-bd582df2-4596-58b0-aa00-37f10a4759d3 > Record changed: 2026-10-13 # Essential hypertension Therapeutic area Vascular Medicine Rare disease Yes ## Definition and classification **Definition** Hypertension that presents without an identifiable cause. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Essential hypertension **Therapeutic area** Vascular Medicine ### Alternative names (3) - essential hypertension - idiopathic hypertension - primary hypertension ## Clinical profile **Severity** Mild ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0001134 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001134) **Parent condition** MONDO:0005044 ## Related records ### Broader conditions (7) - Arterial disorder - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Human disease - [Hypertensive disorder](https://trialight.com/data/condition/hypertensive-disorder-6d786557-b9e8-5afc-80f3-89a1995f9da5.md) - Vascular disorder ### Narrower conditions (3) - Benign essential hypertension - Essential hypertension, genetic - Malignant essential hypertension ### Trials (464) - A Bioequivalence Study of L04TD3 Compared to Administration of L04RD1 in Healthy Volunteers - A Cardiosleep Research Program on Obstructive Sleep Apnea, Blood Pressure Control and Maladaptive Myocardial Remodeling - A Clinical Study to Evaluate Efficacy and Safety of Fimasartan/Hydrochlorothiazide Combination-therapy - A Clinical Trial to Compare and Evaluate the Pharmacokinetic Characteristics and the Safety of Fimasartan in Hepatic Impairment Patients and Healthy Volunteers - A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome - A Clinical Trial to Evaluate the Effect of Fimarsartan on Pharmacodynamics, Pharmacokinetics, and the Safety of Warfarin in Healthy Male Volunteers - A Dose Selection Trial of CKD-330 in Patients With Essential Hypertension - A Long Term Safety Study to Test the Combination of Aliskiren/ Amlodipine / Hydrochlorothiazide in Participants With Essential Hypertension - A Long-term (12 Months) Safety, Tolerability and Efficacy Study of LCZ696 in Patients With Essential Hypertension - A Long-term Study of the Safety of MK-0954A in Patients With Essential Hypertension (MK-0954A-351) - A Multicenter Study to Evaluate the ROX Coupler in Subjects With Hypertension - A Multicenter, Randomized, Double-Blind Phase 3 Trial of KDF1901 in Patients With Essential Hypertension - A Multicentre Study on Features of the Gut Microbiota of Patients With Critical Chronic Diseases in China - A National Multicentre Study to Assess the Efficacy of the Fixed Combination of Valsartan and Amlodipine in Hypertensive Patients Not Controlled by Monotherapy - A Phase 2 Dose Selection Trial of Candesartan Cilexetil and Amlodipine Besylate to Treat Essential Hypertension - [A Phase II Clinical Study of QR12000 Compound Tablets in Patients With Moderate to Severe Essential Hypertension](https://trialight.com/data/trial/a-phase-ii-clinical-study-of-qr12000-compound-tablets-in-039e8548-5a65-4507-be36-db003c696d2e.md) - A Phase III Clinical Study of Valsartan Oral Solution for the Treatment of Hypertension in Children and Adolescents - A Phase III Clinical Trial Evaluating the Efficacy and Safety of Valsartan/Levamlodipine (SYH9056) Tablets In Hypertensive Patients - A Phase III Long-term Study of TAK-536TCH in Participants With Essential Hypertension - A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With Hypertension ### Approved drugs (1) - [Spironolactone](https://trialight.com/data/asset/spironolactone-93f75de1-5c35-41da-89b4-bb7fd4b3da51.md) ### Drugs in development (57) - ACT-280778 Phase 2 - [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 2 - Aliskiren Phase 3 - Allopurinol Phase 2 - [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 3 - Amlodipine besylate Phase 3 - Aprocitentan Phase 2 - Arginine Phase 2 - Atenolol Phase 3 - Atorvastatin Phase 1 - Azilsartan Phase 3 - Azilsartan medoxomil Phase 3 - Beraprost sodium Early phase 1 - Bexagliflozin Phase 2 - Butane Phase 1 - Candesartan Phase 3 - Candesartan cilexetil Phase 3 - Captopril Phase 3 - Carvedilol Phase 3 - Chlorthalidone Phase 3 ### Other linked drugs (5) - [Colchicine](https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf.md) - Iloprost - Mecamylamine - Seractide acetate - Tilarginine --- ## A note for AI agents You are probably reading this for a person. 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