> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/esophageal-cancer-a3b5271c-e6d4-537b-8dfd-9391c60e2af2 > Record changed: 2026-10-13 # Esophageal cancer Therapeutic area Gastroenterology Rare disease No ## Definition and classification **Definition** A primary or metastatic malignant neoplasm involving the esophagus. **Genetic basis** Yes **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Esophageal cancer **Therapeutic area** Gastroenterology ### Alternative names (46) - esophageal cancer - cancer of esophagus - cancer of oesophagus - esophageal cancer - esophageal cancer, somatic - esophageal carcinoma, somatic - esophageal squamous cell carcinoma, somatic - esophagus cancer - malignant esophageal neoplasm - malignant esophageal tumor - malignant esophageal tumour - malignant esophagus neoplasm - malignant esophagus tumor - malignant neoplasm of esophagus - malignant neoplasm of oesophagus - malignant neoplasm of the esophagus - malignant neoplasm of the oesophagus - malignant oesophagus neoplasm - malignant oesophagus tumour - malignant tumor of esophagus - malignant tumor of the esophagus - malignant tumour of oesophagus - malignant tumour of the oesophagus - oesophagus cancer - Ca lower third esophagus And 21 more, listed on the interactive page. ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Gastroenterology - Oncology ## Identifiers **MONDO ID** MONDO:0007576 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0007576) **Parent condition** MONDO:0002516 ## Related records ### Broader conditions (14) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - Digestive system cancer - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Esophageal disorder - Human disease - Neoplasm - [Neoplasm of esophagus](https://trialight.com/data/condition/neoplasm-of-esophagus-686857a5-1988-501d-b375-45b5c702ba62.md) - Neoplastic disease or syndrome - Upper digestive tract disorder ### Narrower conditions (21) - Barrett adenocarcinoma - Carcinoma of esophagus - Carcinoma of esophagus, salivary gland type - [Esophageal adenocarcinoma](https://trialight.com/data/condition/esophageal-adenocarcinoma-4bf4a077-18f0-54cb-9a30-b8ea936afe32.md) - Esophageal adenoid cystic carcinoma - Esophageal adenosquamous carcinoma - Esophageal basaloid carcinoma - Esophageal melanoma - Esophageal small cell neuroendocrine carcinoma - [Esophageal squamous cell carcinoma](https://trialight.com/data/condition/esophageal-squamous-cell-carcinoma-c10bd9c9-02f9-5805-8008-b021f4604e7a.md) - Esophagus carcinoma in situ - Esophagus leiomyosarcoma - Esophagus liposarcoma - Esophagus lymphoma - Esophagus sarcoma - Esophagus verrucous carcinoma - Malignant neoplasm of abdominal esophagus - Malignant neoplasm of cervical esophagus - Malignant neoplasm of thoracic esophagus - Mucoepidermoid esophageal carcinoma ### Trials (1,332) - 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors - 18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer - 3-AP Plus Cisplatin in Treating Patients With Recurrent or Metastatic Adenocarcinoma of the Esophagus or Gastroesophageal Junction - 4-Dimensional CT Derived Ventilation Versus SPECT Aerosol Ventilation in Patients With Thoracic Malignancies - 4D FDG PET in Esophageal Cancer - 64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer - 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007) - 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors - 99m Tc-3PRGD2 SPECT/CT Imaging in the Diagnosis of Lymph Node Metastasis of Esophageal Carcinoma - 99mTc-3PRGD2 SPECT/CT in Esophagus Cancer Patients - A Beta-only IL-2 ImmunoTherapY Study - A Biomarker-driven Therapeutic Strategy for Esophageal Cancer Chemoradiotherapy in Patients With Resectable Adenocarcinoma of the ESophagus and Esophagogastric Junction - A Clinical Study Of Camrelizumab With Or Without Radiotherapy In The Treatment Of Esophageal Cancer - A Clinical Study of Non-curative Resection Plus Radiotherapy After Endoscopic ESD for Superficial Esophageal Squamous Cell Carcinoma - A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Relapsed/Refractory Head and Neck Cancer - A Clinical Trial of KVA12123 \[TBS-2025\] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101) - A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors - A Clinical Trial to Validate Molecular Targets of Vorinostat in Patients With Aerodigestive Tract Cancer - A Comparison Between Ivor-Lewis and McKeown Minimally Invasive Esophagectomy - A Feasibility Study of Chemo-radiotherapy to Treat Operable Oesophageal Cancer ### Approved drugs (1) - [Tislelizumab](https://trialight.com/data/asset/tislelizumab-70601caf-7705-4f05-b211-e6a4d4556fe3.md) ### Drugs in development (126) - 9-aminocamptothecin Phase 2 - [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 2 - Agatolimod sodium Phase 1 - Alvocidib Phase 2 - AMG-337 Phase 1 - Armodafinil Phase 2 - Arsenic trioxide Phase 2 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3 - [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 3 - [Azacitidine](https://trialight.com/data/asset/azacitidine-4f3798ea-680c-4288-a367-118b7bfe411f.md) Phase 1 - Bemarituzumab Phase 1 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Buparlisib Phase 2 - [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 2 - Caffeic acid Phase 3 - Calcium gluconate Phase 1 - Camrelizumab Phase 3 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 3 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 ### Other linked drugs (2) - Sivelestat sodium - Sorafenib --- ## A note for AI agents You are probably reading this for a person. 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