> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/erectile-dysfunction-7faa1d59-dc7e-5236-b25a-3cf871a43869
> Record changed: 2026-10-13

# Erectile dysfunction

Therapeutic area

Reproductive Health

Rare disease

No

## Definition and classification

**Definition**

Persistent or recurrent inability to achieve or to maintain an erection during sexual activity.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Erectile dysfunction

**Therapeutic area**

Reproductive Health

### Alternative names (12)

- erectile dysfunction
- erectile dysfunction
- erectile dysfunction (disease)
- male erectile Disorder
- sexual impotence (finding)
- dysfunction, erectile
- impotence
- impotence, male
- impotence, male sexual
- male impotence
- male sexual impotence
- sexual impotence, Male

## Clinical profile

**All therapeutic areas**

- Reproductive Health

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0005362

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005362)

**Parent condition**

MONDO:0002036

## Related records

### Broader conditions (7)

- Disease
- Disease by body system or component
- Human disease
- Male reproductive system disorder
- Penile disorder
- Physiological sexual disorder
- Reproductive system disorder

### Narrower conditions (2)

- Priapism
- Vasculogenic impotence

### Trials (656)

- 4-aminopyridine Treatment for Nerve Injury
- 6 vs 12 Sessions in Low Intensity Extracorporeal Shock Wave Treatment (LI-ESWT) for Erectile Dysfunction (ED)
- A Bio-psychosocial Sexual Health Intervention for Prostate Cancer Survivors and Partners: a Feasibility Study
- A Bioavailability Study of LY2452473 and Tadalafil
- A Clinical Trial to Investigate the Efficacy and Safety of Tongkat Ali Maca Plus
- A Combined Psycho-pharmacological and Brain Imaging Study of Human Sexuality
- A Comparative Pharmacokinetic and Pharmacodynamic Study of Sildenafil in Adult Smokers and Non Smokers
- A Double-blind "Preferred" Vardenafil Dose Study of QoL and Functional Outcomes in Males With Erectile Dysfunction
- A Multicenter, Double-blind Study to Evaluate the Effect of Pretreatment With a Daily Dose of Sildenafil on the As-Needed Efficacy of Viagra in Men With Erectile Dysfunction and Type 2 Diabetes
- A Multicenter, Open Label, To Evaluate The Efficacy And Satisfaction Of Patrex® In Men With Erectile Dysfunction.
- A Multicenter, Randomized, Parallel Group, Double-Blind, Placebo Controlled, Flexible Dose Escalation Study To Evaluate Sexual And Relationship Satisfaction In The Female Partner Of Men With Erectile Dysfunction Treated With Sildenafil Citrate
- A New Sildenafil Oral Film in Patients With Erectile Dysfunction
- A Phase 1 Trial of LIB-01 in Healthy Participants.
- A Phase I Crossover Study of the Hemodynamic Interactions of Avanafil & Alcohol in Healthy Male Subjects.
- A Phase II, Repeat Single Oral Dose Study of IPED2015 in Healthy Male Subjects With Erectile Dysfunction
- A Pivotal Study of the Bioequivalence of Oral Viagra® and a Test Sublingual Sildenafil Wafer
- A Potential Relationship Between Treatment With Tyrosine Kinase Inhibitors and Erectile Dysfunction in Male Patients With Chronic Myeloid Leukemia
- A Prospective Comparative Study of Autologous Bone Marrow-Derived and Adipose Tissue-Derived Mesenchymal Stem Cells Versus Platelet-Rich Plasma and Standard Therapy in Patients With Organic Erectile Dysfunction
- A Randomised Study of Levitra to Treat Men With Erections Problems and Previously Untreated With Similar Therapy.
- A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses

### Approved drugs (12)

- Alprostadil
- Apomorphine
- Apomorphine hydrochloride
- Avanafil
- Moxisylyte
- Papaverine
- Sildenafil
- Sildenafil citrate
- [Tadalafil](https://trialight.com/data/asset/tadalafil-4b34b94f-a4f3-4c9a-a187-9910e81423ab.md)
- Vardenafil
- Vardenafil hydrochloride
- Yohimbine

### Drugs in development (41)

- [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 1
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 1
- Arginine Phase 2
- BMS-223131 Phase 2
- Bremelanotide Phase 3
- Caficrestat Phase 3
- Ciprofloxacin Early phase 1
- Clavulanic acid Phase 2
- Dapoxetine Phase 3
- Dasantafil Phase 2
- Desipramine Phase 1
- Doxazosin Phase 1
- [Doxycycline](https://trialight.com/data/asset/doxycycline-9994da3d-bd1e-4dba-9a9e-392765b5aa58.md) Early phase 1
- Enalapril Phase 1
- [Erythromycin](https://trialight.com/data/asset/erythromycin-aedb4bea-725f-47b5-99f5-9aee0c68a896.md) Phase 1
- FE 202767 Phase 2
- Fispemifene Phase 2
- Fluvastatin Phase 3
- Gisadenafil Phase 2
- IP-2018 Phase 2

### Other linked drugs (4)

- Conestat alfa
- Naltrexone hydrochloride
- Verapamil
- Yohimbine hydrochloride

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