> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/endometrium-adenocarcinoma-074853a7-50ad-5555-acac-5df9f272841f > Record changed: 2026-10-13 # Endometrium adenocarcinoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** An adenocarcinoma arising from the uterine body cavity. This is the most frequent malignant tumor affecting the uterine body, and is linked to estrogen therapy. Most patients present with uterine bleeding and are over age 40 at the time of diagnosis. The prognosis depends on the stage of the tumor, the depth of the uterine wall invasion, and the histologic subtype. Endometrioid adenocarcinoma is the most frequently seen morphologic variant of endometrial adenocarcinoma. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Endometrium adenocarcinoma **Therapeutic area** Oncology ### Alternative names (9) - endometrium adenocarcinoma - endometrioid carcinoma of endometrium - adenocarcinoma of endometrium - adenocarcinoma of the endometrium - adenocarcinoma, endometrial, malignant - endometrial adenocarcinoma - endometrioid adenoma or carcinoma NOS (morphologic abnormality) - endometrioid adenomas and carcinomas (morphologic abnormality) - endometrium adenocarcinoma ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Reproductive Health ## Identifiers **MONDO ID** MONDO:0005461 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005461) **Parent condition** MONDO:0002447 ## Related records ### Broader conditions (26) - [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - [Endometrial cancer](https://trialight.com/data/condition/endometrial-cancer-4da2a0bc-7943-502b-a698-cc2beccbed8c.md) - [Endometrial carcinoma](https://trialight.com/data/condition/endometrial-carcinoma-d0794a04-ff16-5af6-8fb7-7b3d6bd6c537.md) - Endometrial disorder - Endometrium neoplasm - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - [Female reproductive organ cancer](https://trialight.com/data/condition/female-reproductive-organ-cancer-1207d84e-931f-51b6-90d9-6b2135cdebbb.md) - Female reproductive system disorder - Female reproductive system neoplasm - Glandular cell neoplasm - Human disease - Neoplasm - Neoplastic disease or syndrome - Reproductive system cancer ### Narrower conditions (10) - Endometrial clear cell adenocarcinoma - Endometrial endometrioid adenocarcinoma with spindled epithelial cells - Endometrial mixed adenocarcinoma - Endometrial mucinous adenocarcinoma - Mucin-rich endometrial endometrioid adenocarcinoma - Ovarian endometrioid adenocarcinoma - Ovarian endometrioid adenocarcinoma with squamous differentiation - Oxyphilic endometrial endometrioid adenocarcinoma - Secretory uterine corpus endometrioid adenocarcinoma - Villoglandular endometrial endometrioid adenocarcinoma ### Trials (60) - \[SENTRY\] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer - [A Phase 2 Study of ACR-368 in Endometrial Adenocarcinoma](https://trialight.com/data/trial/a-phase-2-study-of-acr-368-in-endometrial-adenocarcinoma-6a063030-8542-480d-b9a2-e9309f8192d8.md) - A Randomized Pilot Study to Evaluate the Effects of a Short Course of Metformin Versus No Therapy in the Period Prior to Hysterectomy for Grade 1-2 Adenocarcinoma of the Endometrium in Obese Non-Diabetic Women - A Study to Evaluate ELU001 in Patients With Solid Tumors That Overexpress Folate Receptor Alpha (FRĪ±) - A Study to Investigate APL-5125 in Adults With Advanced Solid Tumors - Akt Inhibitor MK2206 in Treating Patients With Recurrent or Advanced Endometrial Cancer - AMT-151 in Patients With Selected Advanced Solid Tumours - Assisted Exercise in Obese Endometrial Cancer Patients - Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer - Cadonilimab (AK104) Plus Chemotherapy in Patients With Recurrent or Advanced Endometrial Cancer - Cediranib Maleate in Treating Patients With Recurrent or Persistent Endometrial Cancer - Cisplatin and Paclitaxel in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cavity Cancer - Clonal Hematopoiesis Chemotherapy and Radiation Effects Study - Combination Chemotherapy Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer - Comparison of Sentinel Lymph Node Applications in Endometrial Cancer Cases Performed With Vaginal Natural Orifice Transluminal Endoscopic Surgery (V-NOTES) and Conventional Laparoscopy - Comparison of Two Combination Chemotherapy Regimens Plus Radiation Therapy in Treating Patients With Stage III or Stage IV Endometrial Cancer - Dalantercept in Treating Patients With Recurrent or Persistent Endometrial Cancer - Dasatinib, Paclitaxel, and Carboplatin in Treating Patients With Stage III-IV or Recurrent Endometrial Cancer - DBC-664 in Adult Patients With Solid Tumors - Diagnostic and Prognostic Value of PTEN Expression in Functional and Pathological Endometrial Biopsies --- ## A note for AI agents You are probably reading this for a person. 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