> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/endometrial-cancer-4da2a0bc-7943-502b-a698-cc2beccbed8c
> Record changed: 2026-10-13

# Endometrial cancer

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

Primary or metastatic malignant neoplasm involving the endometrium (mucous membrane that lines the endometrial cavity).

**Genetic basis**

Yes

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Endometrial cancer

**Therapeutic area**

Oncology

### Alternative names (14)

- endometrial cancer
- endometrial neoplasm
- neoplasm of endometrium
- tumor of endometrium
- tumour of endometrium
- cancer of endometrium
- endometrial cancer
- endometrial cancer, familial, autosomal dominant, somatic mutation
- endometrial cancer, susceptibility to, autosomal dominant, somatic mutation
- endometrial carcinoma, somatic
- endometrium cancer
- malignant endometrial neoplasm
- malignant endometrium neoplasm
- malignant neoplasm of endometrium

## Clinical profile

**Severity**

Severe

### All therapeutic areas (2)

- Oncology
- Reproductive Health

## Identifiers

**MONDO ID**

MONDO:0011962

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0011962)

**Parent condition**

MONDO:0002715

## Related records

### Broader conditions (19)

- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Endometrial disorder
- Endometrium neoplasm
- [Female reproductive organ cancer](https://trialight.com/data/condition/female-reproductive-organ-cancer-1207d84e-931f-51b6-90d9-6b2135cdebbb.md)
- Female reproductive system disorder
- Female reproductive system neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Reproductive system cancer
- Reproductive system disorder
- Reproductive system neoplasm
- [Tumor of uterus](https://trialight.com/data/condition/tumor-of-uterus-0e35fef4-f54a-5086-aa67-9cd577110fd7.md)
- [Uterine cancer](https://trialight.com/data/condition/uterine-cancer-730975f4-97de-54f6-9dc4-0ffc00bae465.md)
- Uterine disorder

### Narrower conditions (23)

- Endometrial adenosquamous carcinoma
- [Endometrial carcinoma](https://trialight.com/data/condition/endometrial-carcinoma-d0794a04-ff16-5af6-8fb7-7b3d6bd6c537.md)
- Endometrial clear cell adenocarcinoma
- Endometrial endometrioid adenocarcinoma with spindled epithelial cells
- Endometrial mixed adenocarcinoma
- Endometrial mucinous adenocarcinoma
- Endometrial small cell carcinoma
- Endometrial squamous cell carcinoma
- Endometrial transitional cell carcinoma
- Endometrial undifferentiated carcinoma
- Endometrioid stromal sarcoma
- Endometrioid stromal sarcoma of the cervix
- Endometrioid stromal sarcoma of the vagina
- [Endometrium adenocarcinoma](https://trialight.com/data/condition/endometrium-adenocarcinoma-074853a7-50ad-5555-acac-5df9f272841f.md)
- Endometrium carcinoma in situ
- Mucin-rich endometrial endometrioid adenocarcinoma
- Ovarian endometrioid adenocarcinoma
- Ovarian endometrioid adenocarcinoma with squamous differentiation
- Oxyphilic endometrial endometrioid adenocarcinoma
- Secretory uterine corpus endometrioid adenocarcinoma

### Trials (1,373)

- (VELA) Study of BLU-222 in Advanced Solid Tumors
- \[F-18\] Fluorothymidine PET/CT Imaging for Pelvic Cancers
- \[SENTRY\] Tailoring Postoperative Management Through Sentinel Lymph Node Biopsy in Low- and Intermediate-Risk Endometrial Cancer
- 177Lu-anti-PD-L1 sdAb in Metastatic Solid Tumors
- 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors
- 18-fluorofuranylnorprogesterone (FFNP) PET/MRI as a Potential Biomarker of Response to Progesterone Therapy
- 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors
- 2D Versus 3D Radical Laparoscopic Hysterectomy for Endometrial Cancer: a Prospective Randomized Trial
- 2D vs 3D Planning for High-Dose Rate (HDR) Gynecological Brachytherapy
- 3 Year Recurrence Free Survival in Ultra-low-risk Endometrial Cancer
- 3D Printed Custom Applicators for HDR BT (DISCO)
- 4FMFES-PET Imaging of Endometrial and Ovarian Cancers
- 68Ga-FAPI-PSMA PET Imaging for the Diagnosis of Solid Tumors
- 7-Hydroxystaurosporine and Irinotecan Hydrochloride in Treating Patients With Metastatic or Unresectable Solid Tumors or Triple Negative Breast Cancer (Currently Accruing Only Triple-negative Breast Cancer Patients Since 6/8/2007)
- A Beta-only IL-2 ImmunoTherapY Study
- A Biomarker Screening Protocol for Participants With Solid Tumors
- A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer
- A Clinical Study of the Anti-cancer Effects of an Investigational Therapy or Chemotherapy in Patients With Recurring Uterine Cancer
- A Clinical Study of the Safety and Effectiveness of an Investigational Cell Therapy Given With and Without an Investigational RNA-based Vaccine in Patients With Organ Tumors
- A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Cervical and Endometrial Cancer

### Approved drugs (2)

- [Dostarlimab](https://trialight.com/data/asset/dostarlimab-aad06b17-e988-4591-813f-4b6cef63860f.md)
- [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md)

### Drugs in development (137)

- [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 2
- Abequolixron Phase 1
- Acasunlimab Phase 2
- [Albumin human](https://trialight.com/data/asset/albumin-human-95414b67-0d38-49d4-91b2-27b1c6c17389.md) Phase 3
- [Alpelisib](https://trialight.com/data/asset/alpelisib-0b0ae0f7-4313-42ef-bbbe-3280ed5ea15c.md) Phase 2
- Alsevalimab Early phase 1
- Alvocidib Phase 2
- Amifostine Phase 2
- Aminopterin Phase 2
- [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 2
- [Anastrozole](https://trialight.com/data/asset/anastrozole-327e05a9-e5b7-41d1-a335-bd8a46453b55.md) Phase 1
- Arzoxifene hydrochloride Phase 2
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 2
- [Atezolizumab](https://trialight.com/data/asset/atezolizumab-2cce6944-73b7-49f4-8125-4e6747997b82.md) Phase 3
- Atorvastatin Early phase 1
- [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 2
- Axitinib Phase 2
- Balstilimab Phase 1
- [Benmelstobart](https://trialight.com/data/asset/benmelstobart-2bff71aa-d2ac-4a5a-9949-c935954a2314.md) Phase 3
- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2

### Other linked drugs (1)

- [Tirzepatide](https://trialight.com/data/asset/tirzepatide-eed85871-eb9c-4712-9102-badfdd99a720.md)

---

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