> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/dry-eye-syndrome-41ae8541-7903-50ab-9b50-168da1d2f619 > Record changed: 2026-10-13 # Dry eye syndrome Therapeutic area Ophthalmology Rare disease No ## Definition and classification **Definition** A syndrome characterized by dryness of the cornea and conjunctiva. It is usually caused by a deficiency in tear production. Symptoms include a feeling of burning eyes and a possible foreign body presence in the eye. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Dry eye syndrome **Therapeutic area** Ophthalmology ### Alternative names (7) - dry eye syndrome - dry eye - dry eye syndrome - dry eye(s) - eye(s), dry - keratoconjunctivitis sicca - sicca, keratoconjunctivitis ## Clinical profile **All therapeutic areas** - Ophthalmology **Severity** Mild ### Disease mechanisms (2) - Inflammatory - Syndromic ## Identifiers **MONDO ID** MONDO:0006733 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006733) **Parent condition** MONDO:0001854 ## Related records ### Broader conditions (16) - Conjunctival disorder - Conjunctivitis - Corneal disorder - Disease - Disease by body system or component - Disease by developmental or physiological process - Disorder of orbital region - Disorder of visual system - Eye adnexa disorder - Eye disorder - Human disease - Inflammatory disease - Keratitis - Keratoconjunctivitis - Lacrimal apparatus disorder - Syndromic disease ### Narrower conditions (1) - Xerophthalmia ### Trials (1,350) - \[KSR-001-P01\]Clinical Trial to Evaluate the Safety, Tolerability and Pharmacokinetic Characteristic of KSR-001 - \[KSR-001-P02\] Phase 2b/3 Study, Evaluate the Efficacy and Safety of KSR-001 in Patients With Dry Eye Syndrome - 0.3% Sodium Hyaluronate in the Treatment of Dry Eye of Diabetic Patients - 2177GCCC:ID'Ing tx Targets and Biomarkers for Ocular Surface Disease in Pt w/ oGVHD - 3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis - 3 Month Study of Cationorm Pro Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis - 3% Diquafosol Ophthalmic Solution for Active Moderate-to-Severe Vernal Keratoconjunctivitis - A 1-Year Study in Multiple Clinics Testing Rebamipide Eye Drops for Dry Eye Compared With a Placebo - A 2-week Clinical Comparison of SYSTANE® Ultra to Sensitive Eyes Rewetting Drops in Contact Lens Wearing Patients. - A Clinical Evaluation of an Investigational Lubricant Eye Gel (FID 115958D) - A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens - A Clinical Study Evaluating Licaminlimab for Dry Eye Disease - A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye - A Clinical Study Evaluating the Safety and Efficacy of SI-614 Ophthalmic Solution in Patients With Dry Eye. - A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES) - A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease - A Clinical Trial to Assess Subjects With Dry Eye Disease. - A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease - A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease - A Clinical Trial to Evaluate the Clinical Efficacy of Cyclosporine 0.1% (Ikervis®) for Moderate to Severe Dry Eye Patients. (IKE-03-SWITCHING) ### Approved drugs (3) - Lifitegrast - Loteprednol etabonate - [Perfluorohexyloctane](https://trialight.com/data/asset/perfluorohexyloctane-a636f5f3-a738-40e0-827a-c242866ab0fc.md) ### Drugs in development (81) - Acetylcysteine Phase 2 - Acoltremon Phase 1 - Amlisimod Phase 2 - Betamethasone Phase 2 - Betamethasone sodium phosphate Phase 2 - Brimonidine Phase 2 - Brimonidine tartrate Phase 3 - BRM-421 Phase 3 - Bromfenac Phase 3 - [Canakinumab](https://trialight.com/data/asset/canakinumab-7cd74b21-082d-4a09-8847-aa6d401bc853.md) Phase 2 - Carbomer 910 Phase 2 - Carboxymethylcellulose sodium Phase 3 - [Cenegermin](https://trialight.com/data/asset/cenegermin-c47bd113-cac2-4c57-a094-530d311415a9.md) Phase 3 - [Cinhyaluronate sodium](https://trialight.com/data/asset/cinhyaluronate-sodium-3032be48-a2e5-444e-9aff-f44e2e320737.md) Phase 3 - Cis-urocanic acid Phase 1 - Cyclosporine Phase 3 - [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 2 - Dexamethasone phosphoric acid Phase 3 - Difluprednate Phase 2 - Diquafosol tetrasodium Phase 3 ### Other linked drugs (4) - Diquafosol - Phenylpropanolamine hydrochloride - Sulfacetamide - Tetracycline --- ## A note for AI agents You are probably reading this for a person. 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