> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44
> Record changed: 2026-10-13

# Digestive system neoplasm

Therapeutic area

Oncology

Rare disease

No

## Definition and classification

**Definition**

A neoplasm (disease) that involves the digestive system.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Digestive system neoplasm

**Therapeutic area**

Oncology

### Alternative names (37)

- digestive system neoplasm
- GI neoplasm
- GI system neoplasm
- GI system tumor
- GI system tumour
- GI tumor
- GI tumour
- digestive neoplasm
- digestive system neoplasm (disease)
- digestive system tumor
- digestive system tumour
- digestive tumor
- digestive tumour
- gastrointestinal neoplasm
- gastrointestinal system neoplasm
- gastrointestinal system tumor
- gastrointestinal system tumour
- gastrointestinal tumor
- gastrointestinal tumour
- neoplasm of GI system
- neoplasm of digestive system
- neoplasm of gastrointestinal system
- neoplasm of the GI system
- neoplasm of the digestive system
- neoplasm of the gastrointestinal system

And 12 more, listed on the interactive page.

## Clinical profile

**All therapeutic areas**

- Oncology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0021223

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0021223)

**Parent condition**

MONDO:0005070

## Related records

### Broader conditions (6)

- Cancer or benign tumor
- Disease
- Disease by etiologic mechanism
- Human disease
- Neoplasm
- Neoplastic disease or syndrome

### Narrower conditions (736)

- Adenocarcinoma of gallbladder and extrahepatic biliary tract
- Adenoid ameloblastoma
- Adenoid cystic carcinoma of oropharynx
- Adenoma of pancreas
- Adenoma of small intestine
- Adenomatoid odontogenic tumor
- Adenomatous colon polyp
- Adenosquamous bile duct carcinoma
- Adenosquamous colon carcinoma
- [Adult hepatocellular carcinoma](https://trialight.com/data/condition/adult-hepatocellular-carcinoma-c10a1a4b-50f0-572a-8bff-bf597d4b7fae.md)
- Aflatoxin-related hepatocellular carcinoma
- Ameloblastic carcinoma
- Ameloblastoma
- Ampulla of vater adenocarcinoma
- Ampulla of vater adenosquamous carcinoma
- Ampulla of vater cancer
- Ampulla of vater clear cell adenocarcinoma
- Ampulla of vater mucinous adenocarcinoma
- Ampulla of vater neoplasm
- Ampulla of vater small cell neuroendocrine carcinoma

### Trials (836)

- 'Penny', a SMS Text-based Chatbot Intervention for Medication Adherence and Side Effect Management Among Patients With GI Cancers
- 131Iodine-Tenatumomab Treatment in Tenascin-C Positive Cancer Patients
- 2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers
- 5-Fluorouracil Followed by Interferon-alfa-2b in Previously-treated Metastatic Gastrointestinal, Kidney, or Lung Cancer
- 68Ga-PMD22 PET/CT Examination Targeting CLDN18.2
- 89Zr-AMG211 PET Imaging Study
- 89Zr-MMOT PET Imaging in Pancreatic and Ovarian Cancer Patients
- A Clinical Safety and Efficacy Study of Mebendazole on GI Cancer or Cancer of Unknown Origin.
- A Clinical Study of Arfolitixorin in Patients With mCRC
- A Clinical Study of TJ004309 With Atezolizumab (TECENTRIQ®) in Patients With Ovarian Cancer and Selected Solid Tumors
- A Clinical Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors
- A Clinical Study on the Safety and Efficacy of CAR-T Therapy for the TM4SF1-positive Tumors of Digestive System
- A Clinicobiological Database in Metastatic Digestive Cancers
- A Comparative Study of CCI, EmSFI, and FTRST Scoring Systems
- A Disposable Endoscopic Closing Device Used for the Closure of Gastrointestinal Tissue
- A Double-Blind, Randomized, Placebo-Controlled Study of the Efficacy and Safety of Weekly Procrit Given to Gastric or Rectal Patients
- A Feasibility Trial of Geriatric Assessment and Management for Older Cancer Patients
- A First in Human Study of PLT012 in Participants With Solid Tumor Cancers
- A First-in-human Study Using BDC-1001 as a Single Agent and in Combination With Nivolumab in Advanced HER2-Expressing Solid Tumors
- A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors

### Drugs in development (13)

- Alectinib Phase 2
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 1
- Flucytosine Phase 1
- [Fluorouracil](https://trialight.com/data/asset/fluorouracil-f8444d73-5c73-4f35-aa71-67d578277450.md) Phase 2
- [Irinotecan hydrochloride](https://trialight.com/data/asset/irinotecan-hydrochloride-c1f6b7df-7c76-40f1-92fe-12d71b1f3b25.md) Phase 1
- [Leucovorin calcium](https://trialight.com/data/asset/leucovorin-calcium-8da292ca-1b92-4365-b525-77d897b1c096.md) Phase 2
- Pasireotide Phase 1
- Picoplatin Phase 1
- [Propranolol](https://trialight.com/data/asset/propranolol-2a170ee3-78ff-4851-bf86-5da33d9a1807.md) Phase 2
- Pyrotinib Phase 2
- [Tislelizumab](https://trialight.com/data/asset/tislelizumab-70601caf-7705-4f05-b211-e6a4d4556fe3.md) Phase 1
- [Trastuzumab](https://trialight.com/data/asset/trastuzumab-0f66b952-86b3-4152-b427-158320504c8a.md) Phase 2
- [Trastuzumab deruxtecan](https://trialight.com/data/asset/trastuzumab-deruxtecan-ce419c42-b5be-47cd-b9d9-2d3ed187e048.md) Phase 2

### Other linked drugs (1)

- Sunitinib malate

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