> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/differentiated-thyroid-carcinoma-d7c5bae1-a4cb-5587-998c-99d7ccc3ba9a > Record changed: 2026-11-04 # Differentiated thyroid carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** Differentiated thyroid carcinoma (DTC), also known as papillary or follicular thyroid carcinoma, is a slow-growing malignancy usually presenting in adults as an asymptomatic thyroid mass. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Differentiated thyroid carcinoma **Therapeutic area** Oncology ### Alternative names (20) - differentiated thyroid carcinoma - Advanced Differentiated Thyroid Gland Carcinoma - differentiated thyroid cancer - Differentiated Thyroid Cancer (DTC) - Differentiated Thyroid Carcinoma (DTC) - differentiated thyroid gland cancer - differentiated thyroid gland carcinoma - Locally Advanced Differentiated Thyroid Gland Carcinoma - Metastatic Differentiated Thyroid Cancer - Metastatic Differentiated Thyroid Gland Carcinoma - papillary or follicular thyroid carcinoma - Recurrent Differentiated Thyroid Gland Carcinoma - Refractory Differentiated Thyroid Gland Carcinoma - thyroid gland differentiated carcinoma - thyroid gland well differentiated carcinoma - Unresectable Differentiated Thyroid Gland Carcinoma - well differentiated thyroid carcinoma - well differentiated thyroid gland carcinoma - well-differentiated thyroid cancer - well-differentiated thyroid carcinoma ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Endocrinology - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015447) ## Identifiers **MONDO ID** MONDO:0015447 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015447) **Parent condition** MONDO:0015075 ## Related records ### Broader conditions (17) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Endocrine gland neoplasm - [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md) - Epithelial neoplasm - Human disease - Malignant endocrine neoplasm - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome - [Thyroid cancer](https://trialight.com/data/condition/thyroid-cancer-44afb6a8-b88e-5e18-b9fd-7b51661c2c23.md) - Thyroid gland carcinoma - [Thyroid gland disorder](https://trialight.com/data/condition/thyroid-gland-disorder-3319c776-b41b-562a-aca8-f1177e191b3f.md) - [Thyroid tumor](https://trialight.com/data/condition/thyroid-tumor-fc2bab9d-d468-5acb-8a62-e5f68e538979.md) ### Narrower conditions (19) - Columnar cell variant thyroid gland papillary carcinoma - Familial medullary thyroid carcinoma - Familial papillary or follicular thyroid carcinoma - Medullary thyroid gland carcinoma - Multicentric papillary thyroid carcinoma - Papillary thyroid Microcarcinoma - Tall cell variant thyroid gland papillary carcinoma - Thyroid cancer, nonmedullary, 1 - Thyroid cancer, nonmedullary, 2 - Thyroid cancer, nonmedullary, 3 - Thyroid cancer, nonmedullary, 4 - Thyroid cancer, nonmedullary, 5 - Thyroid carcinoma, nonmedullary, with or without cell oxyphilia - Thyroid gland diffuse sclerosing papillary carcinoma - Thyroid gland follicular carcinoma - Thyroid gland papillary and follicular carcinoma - Thyroid gland papillary carcinoma - Thyroid Hurthle cell carcinoma - Trabecular follicular adenocarcinoma ### Trials (21) - A Phase II Trial of Cabozantinib for the Treatment of Radioiodine (RAI)-Refractory Differentiated Thyroid Carcinoma (DTC) in the First-line Setting - A Trial of Lenvatinib (E7080) in Radioiodine (131 I)-Refractory Differentiated Thyroid Cancer in China - Bethesda Classification and Risk Stratification in Differentiated Thyroid Carcinoma - Correlation Between TCM Syndrome Factors and TSH Changes of Thyroid Hormone Withdrawal Before Iodine Therapy in Postoperative Patients With Thyroid Cancer - Decision Aid Efficacy in Low Risk Thyroid Cancer - Effect of Lithium Carbonate on Low-Dose Radioiodine Therapy in Early Thyroid Cancer - I-124 PET/CT Based Remnant Radioiodine Ablation Decision Concept in Differentiated Thyroid Cancer - [Long-Term Extension Study for Participants Previously Enrolled in an Exelixis-Sponsored Study](https://trialight.com/data/trial/long-term-extension-study-for-participants-previously-1f9d623b-4584-41d7-bd30-d9e8f8906175.md) - Nintedanib(BIBF1120) in Thyroid Cancer - OnT4-Thyroglobulin Assay Before rhTSH-Aided Radioiodine Ablation - Phase 2 Trial of Apatinib Mesylate in Locally Advanced/Metastatic Differentiated Thyroid Carcinoma - Post-marketing Surveillance on the Safety of CabometyxTM in Korean Patients - Robotic Surgery Via Bilateral Axillo-breast Approach for Relatively Low-risk Papillary Thyroid Carcinoma With Lateral Cervical Lymph Node Metastasis: a Safe and Effective Cosmetic Procedure in the Context of Prevalent Thyroid Ultrasound Screening - Serum Treg/Th17-Related Cytokines and Systemic Inflammatory Indices in Differentiated Thyroid Cancer - Significance of Contralateral Central Lymph Node Dissection in Unilateral cN0 Differentiated Thyroid Carcinoma. - Spanish Study for Molecular Characterization of Thyroid Carcinoma - Study of Efficacy and Safety of Dabrafenib in Combination With Trametinib in Previously Treated Patients With Metastatic, Radio-active Iodine Refractory BRAF V600E Mutation Positive Differentiated Thyroid Cancer - Study of Lenvatinib in Children and Adolescents With Refractory or Relapsed Solid Malignancies and Young Adults With Osteosarcoma - Study of ST-1898 in Locally Advanced or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer - The EMIRATES Study ### Approved drugs (3) - [Lenvatinib](https://trialight.com/data/asset/lenvatinib-44bdd81b-9a97-4a26-9b2b-0d1d8fd79032.md) - Levothyroxine sodium - Liothyronine sodium ### Drugs in development (69) - [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 2 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 1 - Avutometinib Phase 2 - [Benmelstobart](https://trialight.com/data/asset/benmelstobart-2bff71aa-d2ac-4a5a-9949-c935954a2314.md) Phase 2 - [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 3 - Cabozantinib S-malate Phase 2 - [Camrelizumab](https://trialight.com/data/asset/camrelizumab-db95676a-3681-47ee-8647-408fc9391e28.md) Phase 2 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 2 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 - Catequentinib hydrochloride Phase 2 - Cediranib maleate Phase 1 - [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 2 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 2 - CM-4307 Phase 2 - Cobimetinib Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2 - Dabrafenib Phase 3 - [Defactinib](https://trialight.com/data/asset/defactinib-93d3f8e7-960f-4e54-9e6e-fd0a1504d053.md) Phase 2 - [Denosumab](https://trialight.com/data/asset/denosumab-9ee8731d-42aa-4d04-abbd-9dffa084523f.md) Phase 2 - [Doxorubicin hydrochloride](https://trialight.com/data/asset/doxorubicin-hydrochloride-2e3493ba-9766-475e-aa7d-f2debf111de5.md) Phase 2 ### Other linked drugs (6) - Alendronate sodium - Liothyronine - Liothyronine I 131 - [Metformin](https://trialight.com/data/asset/metformin-0292cbe3-3a2f-4db7-b783-270ef048c3b4.md) - [Sacituzumab tirumotecan](https://trialight.com/data/asset/sacituzumab-tirumotecan-25c916a3-8178-42d0-a6e5-c6d3a4149237.md) - [Tislelizumab](https://trialight.com/data/asset/tislelizumab-70601caf-7705-4f05-b211-e6a4d4556fe3.md) --- ## A note for AI agents You are probably reading this for a person. 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