> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/diarrheal-disease-623389f5-2a35-5350-9dae-f2dc4bc0fc34 > Record changed: 2026-10-13 # Diarrheal disease Therapeutic area Gastroenterology Rare disease No ## Definition and classification **Definition** The condition of having at least three loose or liquid bowel movements each day. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Diarrheal disease **Therapeutic area** Gastroenterology ### Alternative names (8) - diarrheal disease - diarrhea - diarrheal disease - diarrheal disorder - diarrhoea - frequent stools - loose stools - diarrhoea of presumed infectious origin ## Clinical profile **All therapeutic areas** - Gastroenterology **Severity** Mild ## Identifiers **MONDO ID** MONDO:0001673 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001673) **Parent condition** MONDO:0004335 ## Related records ### Broader conditions (4) - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - Disease - Disease by body system or component - Human disease ### Narrower conditions (34) - Acute diarrhea - Amebic dysentery - Chronic diarrhea due to glucoamylase deficiency - Chronic diarrheal disease - Congenital diarrhea - Congenital diarrhea 5 with tufting enteropathy - Congenital diarrhea 6 - Congenital diarrhea 7 with exudative enteropathy - Congenital malabsorptive diarrhea 4 - Congenital secretory chloride diarrhea 1 - Congenital secretory diarrhea - Congenital secretory sodium diarrhea 3 - Congenital secretory sodium diarrhea 8 - Congenital sodium diarrhea - Diarrhea 10, protein-losing enteropathy type - Diarrhea 11, malabsorptive, congenital - Diarrhea 12, with microvillus atrophy - Diarrhea 13 - Diarrhea 14, congenital - Diarrhea 15, congenital ### Trials (709) - "Alcohol Based Hand Sanitizers for the Prevention of Acute Diarrheal Disease and Acute Respiratory Infection in Children Under 5 Attending Childcare Centers in Bogotá, Cundinamarca and Tolima, in Colombia: a Cluster Randomized Control Trial" - 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) - 12-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) - 52-Week Efficacy and Safety Study of Ibodutant in Women With Irritable Bowel Syndrome With Diarrhea (IBS-D) - 64N Nutraceutical for the Prevention of Childhood Diarrhea and Pneumonia in Low Resource Settings - A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS - A Baseline Study in Support of Clinical Evaluation of an Oral Shigella Vaccine Development in Africa - A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health - A Comparison of Fidaxomicin and Vancomycin in Patients With CDI Receiving Antibiotics for Concurrent Infections - A Comparison of Three Medications to Treat Diarrhea in Adults. - A Controlled Trial of Plantain Powder in Infantile Diarrhea - A Dose-escalating Study to Evaluate the Immunogenicity and Safety of Rotavin-M1 Vaccine in Healthy Infants - A Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Orally Administered SP-303 for the Treatment of Diarrhea in Acquired Immunodeficiency Syndrome (AIDS) Patients - A Four Arm Study to Evaluate the Safety and Efficacy of 3 Different Doses of RVX-100 Versus Placebo in Subjects With Irritable Bowel Syndrome Accompanied by Diarrhea (IBS-D) - A Longitudinal Study to Identify IBS Phenotypes Using Fecal Microbiota and Hydrogen Breath Testing - A Multi-center, Single-arm Trial Exploring the Safety and Clinical Effectiveness of RBX2660 Administered by Colonoscopy to Adults With Recurrent Clostridioides Difficile Infection - A Multi-Strain Probiotic Reduces the Frequency of Diarrhea in IBS-D Patients - A Multicenter Placebo-Controlled Dose Titration Study to Evaluate the Efficacy and Safety of Sandostatin (SMS 201-995) in the Treatment of Patients With Acquired Immunodeficiency Related Diarrhea - A Multicenter Placebo-Controlled Double Blind Study to Evaluate the Efficacy and Safety of Sandostatin ( SMS 201-995 ) in Patients With Acquired Immunodeficiency Related Diarrhea Who Were Either "Responders" or "Non-Responders" in a Prior Placebo-Controlled Double-Blind Sandostatin Study. - A Novel Iron Supplement for Athletes: Phase I ### Approved drugs (10) - Bismuth subsalicylate - Crofelemer - Eluxadoline - Fidaxomicin - Loperamide hydrochloride - Nitazoxanide - Rifamycin sodium - Rifaximin - Telotristat etiprate - Vancomycin ### Drugs in development (42) - Actoxumab Phase 3 - [Amoxicillin](https://trialight.com/data/asset/amoxicillin-09050e6a-69b4-42d1-b3eb-79212edcf388.md) Early phase 1 - Amylase (pancrelipase) Phase 3 - Azithromycin Phase 3 - Bifidobacterium SPP. Phase 2 - [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) Phase 2 - [Calcium carbonate](https://trialight.com/data/asset/calcium-carbonate-37e10d9b-34b0-4b9a-ad7f-b08adfd15b03.md) Phase 3 - Ciprofloxacin Phase 3 - Clavulanic acid Early phase 1 - Diethylhomospermine Phase 1 - Elsiglutide Phase 2 - Glutamine Phase 3 - Glycine Phase 3 - IOWH-032 Phase 2 - [Irinotecan hydrochloride](https://trialight.com/data/asset/irinotecan-hydrochloride-c1f6b7df-7c76-40f1-92fe-12d71b1f3b25.md) Phase 3 - Lactobacillus acidophilus Phase 2 - Lactoferrin, bovine Phase 2 - Lactose, anhydrous Phase 3 - Lagatide Phase 2 - Lamivudine Phase 3 ### Other linked drugs (5) - [Cholestyramine](https://trialight.com/data/asset/cholestyramine-02403ab6-2c23-416a-ba64-dd03a00539a1.md) - CO-trimoxazole - Diphenoxylate - Furazolidone - Ramosetron hydrochloride --- ## A note for AI agents You are probably reading this for a person. 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