> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/diabetic-neuropathy-63ebffb4-5198-5c33-9efc-67d7af390754 > Record changed: 2026-11-04 # Diabetic neuropathy Therapeutic area Neurology Rare disease No ## Definition and classification **Definition** A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Diabetic neuropathy **Therapeutic area** Neurology ### Alternative names (3) - diabetic neuropathy - Diabetic Neuropathy, Distal Symmetric Polyneuropathy (Manifestation) - Diabetic Neuropathy, Painful ## Clinical profile **All therapeutic areas** - Neurology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006626) **Severity** Severe ## Identifiers **MONDO ID** MONDO:0006626 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006626) **Parent condition** MONDO:0005244 ## Related records ### Broader conditions (7) - Disease - Disease by body system or component - Human disease - [Nervous system disorder](https://trialight.com/data/condition/nervous-system-disorder-541eb3ed-9656-574d-babf-28139b060a42.md) - Neuromuscular disease - Peripheral nervous system disorder - Peripheral neuropathy ### Narrower conditions (2) - Diabetic autonomic neuropathy - Diabetic polyneuropathy ### Trials (750) - 0.075% Capsaicin Lotion for the Treatment of Painful Diabetic Neuropathy - 12-Month Efficacy and Safety of Diepalrestat in Adults With Diabetic Peripheral Neuropathy, a DB, Placebo-Controlled Study - 24-hour Blood Pressure Dynamics and Autonomic Adrenergic Regulation in Type 2 Diabetics - 3D Printed vs Ready-to-Wear Insoles for Diabetic Neuropathy - A 12-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Painful Peripheral Neuropathy - A 2-part Trial to Learn More About How BAY1817080 Works, How Safe it is, and What the Right Dose is for Participants With Diabetic Neuropathic Pain - A 24-Week Study of Topical Pirenzepine or Placebo in Type 2 Diabetic Patients (T2DM) With Peripheral Neuropathy - A 6-Month Extension Study of VMDN-003-2 to Assess Engensis in Participants With Painful Diabetic Peripheral Neuropathy - A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05). - A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Diabetic Peripheral Neuropathic Pain - A Clinical Outcomes Study to Measure Reduction in Pain and Numbness During Administration of an Amino Acid Formulation in Subjects Diagnosed With Peripheral Neuropathy - A Clinical Trial To Evaluate PF-05089771 On Its Own And As An Add-On Therapy To Pregabalin (Lyrica) For The Treatment Of Pain Due To Diabetic Peripheral Neuropathy (DPN) - A Clinical Trial to Study the Effects GRC 17536 in Patients With Painful Diabetic Peripheral Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients). - A Clinical Trial to Study the Effects of GRC 17536 in Patients With Painful Diabetic Neuropathy (Painful Extremities Due to Peripheral Nerve Damage in Diabetic Patients) - [A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)](https://trialight.com/data/trial/a-dose-ranging-study-in-patients-with-diabetic-peripheral-15fadde4-ad6f-4f8b-aba2-0387cbfa7a02.md) - A Double-Blind, Placebo-Controlled Study of Fermented Deglycyrrhizinated Licorice Extract - A Follow-On Trial to Assess the Long Term Safety and Efficacy of SPM 927 in Painful Distal Diabetic Neuropathy - A Long-term Safety Study With Tapentadol ER and Oxycodone CR in Patients With Moderate to Severe Pain Due to Chronic, Painful Diabetic Peripheral Neuropathy (DPN) - A Long-term Study for the Treatment of Painful Diabetic Neuropathy - A Long-Term Study To Evaluate Safety And Efficacy Of Pregabalin For Pain Associated With Diabetic Peripheral Neuropathy ### Approved drugs (2) - Duloxetine hydrochloride - Epalrestat ### Drugs in development (106) - [Acetaminophen](https://trialight.com/data/asset/acetaminophen-04ea33a5-49ee-4a1b-ad16-54627012140e.md) Phase 3 - Actovegin Phase 3 - Amitriptyline Phase 2 - Ascorbic acid Phase 1 - Astaxanthin Phase 2 - AZD2066 Phase 2 - Benfotiamine Phase 3 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 1 - Bicifadine Phase 2 - Bicifadine hydrochloride Phase 2 - BIIB-095 Phase 1 - [Cannabidiol](https://trialight.com/data/asset/cannabidiol-e1ac1a9a-1111-460c-8a8f-5216571adce8.md) Phase 2 - Cannabinol Phase 1 - Capsaicin Phase 3 - Carisbamate Phase 2 - CBX-129801 Phase 2 - Cebranopadol Phase 3 - Centella asiatica extract Phase 2 - [Clofutriben](https://trialight.com/data/asset/clofutriben-7ea2842a-5d39-4347-893c-990204f42a51.md) Phase 2 - Clonidine Phase 2 ### Other linked drugs (11) - Botulinum toxin type A - Cholecalciferol - Dextrose - Diphenhydramine - Diphenhydramine citrate - Human immunoglobulin G - Letibotulinumtoxina - Liraglutide - [Onabotulinumtoxina](https://trialight.com/data/asset/onabotulinumtoxina-afd3f88c-ad60-44a6-a49b-878bf7763eaa.md) - Pirenzepine hydrochloride - Zenarestat --- ## A note for AI agents You are probably reading this for a person. 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