> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/diabetes-insipidus-eb0e3300-ebb1-5892-a012-f19eda2b45b3
> Record changed: 2026-10-13

# Diabetes insipidus

Therapeutic area

Nephrology

Rare disease

No

## Definition and classification

**Definition**

A disorder characterized by excretion of large amounts of urine, accompanied by excessive thirst. Causes include deficiency of antidiuretic hormone or failure of the kidneys to respond to antidiuretic hormone. It may also be drug-related.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Diabetes insipidus

**Alternative names**

- diabetes insipidus

**Therapeutic area**

Nephrology

## Clinical profile

**All therapeutic areas**

- Nephrology

**Severity**

Mild

## Identifiers

**MONDO ID**

MONDO:0004782

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004782)

**Parent condition**

MONDO:0005240

## Related records

### Broader conditions (5)

- Disease
- Disease by body system or component
- Human disease
- [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md)
- [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md)

### Narrower conditions (6)

- Diabetes insipidus, nephrogenic, autosomal
- Diabetes insipidus, nephrogenic, X-linked
- Dipsogenic diabetes insipidus
- Gestational diabetes insipidus
- Nephrogenic diabetes insipidus
- Neurohypophyseal diabetes insipidus

### Trials (188)

- "SALT Trial" Study of Ascending Levels of Tolvaptan in Hyponatremia
- 1-deamino 8-d-arginine Vasopressin (DDAVP) in Percutaneous Ultrasound-guided Renal Biopsy
- A Study in Adult Males With X-linked Congenital Nephrogenic Diabetes Insipidus to Test the Effects of NDI-5001 Given for Multiple Days and to Test How NDI-5001 is Tolerated and Taken up in the Body
- A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
- Accelerated Rule Out of Myocardial Infarction
- Acute Heart Failure Patients With High Copeptin Treated With Tolvaptan Targets Increased AVP Activation for Treatment (ACTIVATE)
- ADHD Electrophysiological Subtypes and Implications in Transcranial Direct-current Stimulation
- AMCPR (Augmented-Medication CardioPulmonary Resuscitation) Trial for OHCA
- Angiotensin II vs. Vasopressin in Septic Shock
- Antidiuretic Function Before and During Treatment With SGLT2 Inhibitors
- Argipressin's Influence on Blood Loss During Hepatic Resection
- Assessment of Circulating Copeptin Levels in Healthy Subjects and Patients With Renal Insufficiency After Oral Water Load and Hypertonic Saline Infusion
- Atrial and Brain Natriuretic Peptides in Bronchiolitis
- AVERT Shock: Arginine Vasopressin During the Early Resuscitation of Traumatic Shock
- Biological Basis of Individual Variation in Social Cooperation
- Biomarkers In Seizure To Predict Recurrence and Severe Outcomes
- Botulinum Toxin A for Treatment of Catocholamine Induced Finger Necrosis
- Brain Imaging Study of Adults With Autism Spectrum Disorders
- CAlcium and VAsopressin Following Injury Early Resuscitation (CAVALIER) Trial
- Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation

### Approved drugs (2)

- Desmopressin acetate
- [Vasopressin](https://trialight.com/data/asset/vasopressin-592303bd-1d7e-43c7-af55-8c1dcb6024f0.md)

### Drugs in development (4)

- Atorvastatin Phase 2
- Desmopressin Phase 3
- Metformin Phase 1
- [Oxytocin](https://trialight.com/data/asset/oxytocin-787cf970-fce1-4bab-b1c9-6d816e9784fb.md) Phase 1

---

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