> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/dengue-disease-0cfddf8e-48a2-5a1f-b450-9f1e1a1d82c7 > Record changed: 2026-10-13 # Dengue disease Therapeutic area Infectious Disease Rare disease Yes ## Definition and classification **Definition** Dengue fever (DF), caused by dengue virus, is an arboviral disease characterized by an initial non-specific febrile illness that can sometimes progress to more severe forms manifesting capillary leakage and hemorrhage (dengue hemorrhagic fever, or DHF) and shock (dengue shock syndrome, or DSS). **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Dengue disease **Therapeutic area** Infectious Disease ### Alternative names (13) - dengue disease - DF - Dengue - Dengue fever - Dengue virus caused disease or disorder - Dengue virus disease or disorder - Dengue virus infection - Dengue virus infectious disease - break bone fever - Philippine hemorrhagic fever - Singapore hemorrhagic fever - Thai hemorrhagic fever - hemorrhagic dengue ## Clinical profile **Disease mechanisms** - Acquired **All therapeutic areas** - Infectious Disease **Severity** Severe ## Identifiers **MONDO ID** MONDO:0005502 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005502) **Parent condition** MONDO:0005763 ## Related records ### Broader conditions (9) - Disease - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - Flaviviridae infectious disease - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - Primary viral infectious disease - [Vector-borne disease](https://trialight.com/data/condition/vector-borne-disease-3bb0ac2f-6d8c-5d5c-9027-84b59b878a24.md) - [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) ### Narrower conditions (3) - Asymptomatic dengue - Dengue hemorrhagic fever - Dengue shock syndrome ### Trials (272) - A Clinical Study to Evaluate TV003 in Healthy Adults in Taiwan - A Cluster-randomized Trial to EValuate the Efficacy of Wolbachia-InfecTed Aedes Aegypti Mosquitoes in Reducing the Incidence of Arboviral Infection in Brazil (EVITA Dengue) - A Cohort Study to Determine the Incidence of Dengue Fever and to Build Capacity for Dengue Vaccine Trials in Dengue-endemic Regions of South Asia - A Controlled Human Infection Model of Dengue - A Dengue Sero-prevalence Study in the Metropolitan Area of Buenos Aires - A Phase I/II Trial of a Tetravalent Live Attenuated DEN Vaccine in Flavivirus Antibody Naive Children - A Phase I/II Trial of a Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naïve Children - A Phase I/II Trial of Tetravalent Live Attenuated Dengue Vaccine in Flavivirus Antibody Naive Infants - A Phase II Trial of a Live Attenuated Virus Tetravalent Dengue Vaccine in Healthy Adults in Thailand - A Phase-I Study of a Nanoparticle-based Peptide Vaccine Against Dengue Virus - A Pilot Study Examining for the Presence of Fecal Coliforms and Tropical Diseases in Peru - A Study in Children and Teenagers to Learn if a TDV Dengue Vaccination Lowers the Chance of Hospital Stays for Dengue - A Study of 2 Doses of Tetravalent Dengue Vaccine (TDV) in Infants and Toddlers - A Study of Balapiravir in Patients With Dengue Virus Infection - A Study of CP-COV03 Compared With Placebo in Participants With Dengue (Part 1) and Dengue-like Illness (Part 2) - A Study of Dengue Tetravalent Vaccine (TDV) in Adults (Age 45 to 60 and >60 to 79 Years) - A Study of Dengue Tetravalent Vaccine (TDV) in Healthy Participants in Japan - A Study of Dengue Vaccine in Healthy Toddlers Aged 12 to 15 Months in the Philippines - [A Study of JNJ-64281802 for the Prevention of Dengue Infection](https://trialight.com/data/trial/a-study-of-jnj-64281802-for-the-prevention-of-dengue-e8434ed4-9db5-46ac-bb68-1f49f50d0c63.md) - A Study of JNJ-64281802 in Participants With Confirmed Dengue Fever ### Approved drugs (2) - Chimeric yellow fever dengue virus, live attenuated - Dengue virus, live attenuated ### Drugs in development (14) - [Aluminum hydroxide](https://trialight.com/data/asset/aluminum-hydroxide-a0230a1f-a5e2-439f-baa2-2b988b59e46d.md) Phase 1 - Celgosivir Phase 1 - [Cholecalciferol](https://trialight.com/data/asset/cholecalciferol-c9dc6a9a-8bc7-4070-a34e-535013073648.md) Phase 2 - [Diphtheria toxoid](https://trialight.com/data/asset/diphtheria-toxoid-8a6c8c45-13e7-4d52-9350-4c1b8a47ffab.md) Phase 3 - IC14 Phase 2 - [Ivermectin](https://trialight.com/data/asset/ivermectin-92b3d34e-69c8-464b-98da-d0f165a74513.md) Phase 2 - Melatonin Phase 2 - Modipafant Phase 1 - [Mosnodenvir](https://trialight.com/data/asset/mosnodenvir-5b06a242-d5c4-407d-9282-3ca833517ccc.md) Phase 2 - Pertussis vaccine adsorbed Phase 3 - Resomelagon Phase 2 - [Sodium chloride](https://trialight.com/data/asset/sodium-chloride-a67c33bc-45ef-42e4-8022-d121f0a86585.md) Phase 1 - [Tetanus toxoid](https://trialight.com/data/asset/tetanus-toxoid-dd6989f1-5729-447f-81e2-00892bc7a4f6.md) Phase 3 - Zanamivir Phase 2 --- ## A note for AI agents You are probably reading this for a person. 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