> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/dementia-c61efc95-c071-50d2-9df7-acb34b2a720c > Record changed: 2026-10-13 # Dementia Rare disease No ## Definition and classification **Definition** Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Dementia ### Alternative names (3) - dementia - dementia - dementia (disease) ## Clinical profile **Severity** Severe ## Identifiers **MONDO ID** MONDO:0001627 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0001627) **Parent condition** MONDO:0002039 ## Related records ### Broader conditions (5) - Cognitive disorder - Disease - Disease by developmental or physiological process - Human disease - Psychiatric disorder ### Narrower conditions (159) - Aceruloplasminemia - Adrenoleukodystrophy - Adrenomyeloneuropathy - AIDS dementia complex - [Alzheimer disease](https://trialight.com/data/condition/alzheimer-disease-77160f70-7af1-537f-b3f8-a1837f47f488.md) - Alzheimer disease 10 - Alzheimer disease 11 - Alzheimer disease 12 - Alzheimer disease 13 - Alzheimer disease 14 - Alzheimer disease 16 - Alzheimer disease 17 - Alzheimer disease 18 - Alzheimer disease 19 - Alzheimer disease 2 - Alzheimer disease 3 - Alzheimer disease 4 - Alzheimer disease 5 - Alzheimer disease 6 - Alzheimer disease 7 ### Trials (2,307) - "Healthy Actions and Lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program" - "Living Together With Dementia"\_Creation and Validation of a Training Program for Family Caregivers of People With Dementia to Live at Home - \[18F\]-MFBG Versus \[123I\]-MIBG and \[18F\]-PE2I in PD vs. MSA and DLB vs. AD - 10-Year Survival After Acute Hip Fracture in Patients With Preclinical/Clinical Alzheimer Pathology - 100-Year Human Aging Study - 11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia Syndromes - 18-months Safety Follow-up Study of AADvac1, an Active Tau Vaccine for Alzheimer's Disease - 3D Team Care for Cognitively Vulnerable Older Adults - 5-Cog 2.0: A Pragmatic Clinical Trial - 5-Cog Battery for Detecting Cognitive Impairment and Dementia - A 24-Month Study to Evaluate the Efficacy and Safety of Elenbecestat (E2609) in Participants With Early Alzheimer's Disease - A 24-Week Efficacy, Safety and Tolerability of Rivastigmine Patch Study in Patients With Probable Alzheimer's Disease - A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease - A 3 Year Study to Evaluate the Safety and Efficacy of Low Dose Ladostigil in Patients With Mild Cognitive Impairment - A Behavioural Sleep Intervention for People With Mild Cognitive Impairment and Mild Dementia - A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's Disease - A Bridging Study on Efficacy and Safety of \[18F\]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population - A Care Empowerment Program Using Virtual Reality for Family Caregivers of People With Dementia - A Clinical Decision Support Tool for Assessing the Ability to Decide on Returning Home in Elderly Patients with Cognitive Impairments - A Clinical Study Evaluating the Efficacy and Safety of RPh201 Treatment in Individuals With Alzheimer's Disease With or Without Coexisting Cerebrovascular Disease ### Approved drugs (15) - [Aducanumab](https://trialight.com/data/asset/aducanumab-d7f09a77-3bba-47ee-b5c6-b358810893be.md) - Benzgalantamine gluconate - [Donanemab](https://trialight.com/data/asset/donanemab-05021786-bb73-4502-9e7d-3cbd9f71b58f.md) - Donepezil - Donepezil hydrochloride - Galantamine - Galantamine hydrobromide - Ginkgo - Ioflupane I 123 - [Lecanemab](https://trialight.com/data/asset/lecanemab-49c04892-5218-40d4-bf54-c66ea2ad6d64.md) - Memantine - Memantine hydrochloride - Rivastigmine - Rivastigmine tartrate - Tacrine ### Drugs in development (129) - Acamprosate Phase 3 - Agomelatine Phase 3 - Alprazolam Phase 3 - Altropane I-123 Phase 3 - [Ambroxol](https://trialight.com/data/asset/ambroxol-bc0c5848-603d-4f8a-bc12-a4bba0b74621.md) Phase 2 - Amisulpride Phase 3 - Amitriptyline Phase 3 - [Aripiprazole](https://trialight.com/data/asset/aripiprazole-ca9997bd-e762-4bd5-ae57-3df4e68a30dd.md) Phase 3 - Benperidol Phase 3 - Biperiden Phase 3 - Bosutinib Phase 1 - Bromazepam Phase 3 - Bromperidol Phase 3 - Brotizolam Phase 3 - Bupropion Phase 3 - Buspirone Phase 3 - Cannabinol Phase 2 - Carbamazepine Phase 3 - Chloral hydrate Phase 3 - Chlorprothixene Phase 3 ### Other linked drugs (6) - BIIB-080 - Buntanetap - Cyclandelate - Flortaucipir F 18 - Indeloxazine - Oxiracetam --- ## A note for AI agents You are probably reading this for a person. 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