> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/cytomegalovirus-infection-33aa640c-a359-5979-84a0-c70ac00df24d > Record changed: 2026-10-13 # Cytomegalovirus infection Therapeutic area Infectious Disease Rare disease No ## Definition and classification **Definition** A herpesvirus infection caused by Cytomegalovirus. Healthy individuals generally do not produce symptoms. However, the infection may be life-threatening in affected immunocompromised patients. The virus may cause retinitis, esophagitis, gastritis, and colitis. Morphologically, it is characterized by the presence of intranuclear inclusion bodies. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Cytomegalovirus infection **Therapeutic area** Infectious Disease ### Alternative names (4) - cytomegalovirus infection - CMV infection - Cytomegaloviral infection - HCMV infection ## Clinical profile **Disease mechanisms** - Acquired **All therapeutic areas** - Infectious Disease **Severity** Severe ## Identifiers **MONDO ID** MONDO:0005132 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005132) **Parent condition** MONDO:0005794 ## Related records ### Broader conditions (8) - Disease - Disease by etiologic mechanism - Disease of primarily extrinsic mechanism - [Herpesviridae infectious disease](https://trialight.com/data/condition/herpesviridae-infectious-disease-aebfcafe-83be-52c0-b83f-f857b2e24dba.md) - Human disease - [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md) - Primary viral infectious disease - [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md) ### Narrower conditions (5) - Cytomegalovirus pneumonia - Cytomegalovirus pneumonia due to NOS2 deficiency - Cytomegalovirus retinitis - Fetal cytomegalovirus syndrome - Idiopathic disseminated cytomegalovirus infection ### Trials (369) - (Val)Ganciclovir TDM in Transplant Recipients - A Clinical Trial of an Alphavirus Replicon Vaccine for Cytomegalovirus (CMV) - A Cohort Study of Congenital Cytomegalovirus Infection Among Pregnant Women and Their Newborns in China - A Comparison of HIV-Infected Patients With and Without Opportunistic (AIDS-Related) Infection - A Cross-sectional Study of Congenital Cytomegalovirus Infection in Newborns in China - A Cytomegalovirus-Directed Vaccine (CMV-alphaDC1) for Preventing Cytomegalovirus Infection or Reactivation in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation - A Dose-Escalation Study Evaluating Safety and Tolerability of Viral-Specific T Cells Against CMV in Adult Solid Organ Transplant Recipients - A French Cohort of Transplant Recipients With CMV Infection : Risk Factors for Antiviral Resistance in the Prophylaxis Era. - A Long-Term Extension Study to Evaluate the Immunogenicity and Safety of Cytomegalovirus (CMV) mRNA-1647 Vaccine - A Multicenter Study of Oral Versus Intravenous Hydration in AIDS Patients With CMV Retinitis Treated With Foscavir (Foscarnet Sodium) - A Multicenter, Double Blind, Comparative Study of Zidovudine Alone Versus Zidovudine and Acyclovir as Treatment for HIV-Infected Patients With CD4+ Counts Less Than 200 Cells/mm3 - A Multiple Dose Crossover Pharmacokinetics Study to Evaluate the Effects of Food on the Absorption of Oral Ganciclovir - A Pharmacokinetic and Tolerance Study of Oral Ganciclovir in HIV-Infected Children With Asymptomatic Cytomegalovirus Infection and Low CD4 Cell Counts or Quiescent Cytomegalovirus Disease - A Phase 2a Study of IV BCV in Subjects With Adenovirus Infection - A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus - A Phase 3 Study of Brincidofovir Versus Valganciclovir for the Prevention of Cytomegalovirus Disease - A Phase I Pharmacokinetic and Tolerance Study of 28-Day Regimens of Oral Ganciclovir - A Phase I Pharmacokinetic Study in HIV-Positive Subjects of Oral Ganciclovir and Concomitant Antiretroviral Zidovudine and Didanosine - A Phase I/II Open-Labelled Trial of Intravitreal Ganciclovir Salvage Therapy for AIDS Patients With Active CMV Retinitis Who Are Intolerant of Systemic Therapy - A Phase I/II Pilot Treatment Study Of CSF Penetration And Response To Ganciclovir And Foscarnet In CMV Neurologic Disease. ### Approved drugs (2) - Letermovir - [Maribavir](https://trialight.com/data/asset/maribavir-d159b255-857b-4919-a860-55850975c16a.md) ### Drugs in development (23) - [Acyclovir](https://trialight.com/data/asset/acyclovir-69352556-3ccf-40be-9470-76b950dab32b.md) Phase 3 - Acyclovir sodium Phase 3 - Adefovir dipivoxil Phase 3 - Aldesleukin Phase 1 - [Artesunate](https://trialight.com/data/asset/artesunate-586f50f5-bb73-43da-8a18-5a2743da577b.md) Phase 3 - Brincidofovir Phase 3 - Cidofovir Phase 3 - Dextromethorphan Phase 1 - [Digoxin](https://trialight.com/data/asset/digoxin-9928e38a-813e-4948-9d65-9088ba40a442.md) Phase 1 - [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md) Phase 3 - Filociclovir Phase 1 - Foscarnet Phase 3 - Ganciclovir Phase 3 - Levocarnitine Phase 3 - MCMV-3068A Phase 2 - Mycophenolic acid Phase 3 - Phenol Phase 3 - Sevirumab Phase 1 - TCN-202 Phase 1 - [Temozolomide](https://trialight.com/data/asset/temozolomide-3fac1b09-bcc5-4875-871e-2cc6460dc731.md) Phase 1 ### Other linked drugs (3) - Adimlecleucel - Fomivirsen sodium - Regavirumab --- ## A note for AI agents You are probably reading this for a person. 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