> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/cutaneous-lupus-erythematosus-d8209c16-c236-521f-8fd1-cd89b5810e23 > Record changed: 2026-10-13 # Cutaneous lupus erythematosus Therapeutic area Immunology Rare disease No ## Definition and classification **Definition** An autoimmune disorder that manifests as different lupus-specific skin disorders; it can occur with systemic lupus erythematosus, or as a singular disease. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Cutaneous lupus erythematosus **Therapeutic area** Immunology ### Alternative names (2) - cutaneous lupus erythematosus - lupus erythematosus, cutaneous ## Clinical profile **Severity** Moderate ### All therapeutic areas (2) - Immunology - Rheumatology ## Identifiers **MONDO ID** MONDO:0005282 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005282) **Parent condition** MONDO:0004670 ## Related records ### Broader conditions (8) - [Autoimmune disease](https://trialight.com/data/condition/autoimmune-disease-8a8fd8aa-2d04-5f24-b839-ba96a70c11e9.md) - [Connective tissue disorder](https://trialight.com/data/condition/connective-tissue-disorder-3df54ecd-c080-5b4c-b60d-fab4846ea17b.md) - Disease - Disease by body system or component - Human disease - [Immune system disorder](https://trialight.com/data/condition/immune-system-disorder-24846188-b462-515c-bb34-142255a648c8.md) - Lupus erythematosus - [Rheumatic disorder](https://trialight.com/data/condition/rheumatic-disorder-e863530e-2c28-5a33-b1be-d12fa4d746b9.md) ### Narrower conditions (12) - Bullous systemic lupus erythematosus - Chilblain lupus - Chilblain lupus 1 - Chilblain lupus 2 - Chronic cutaneous lupus erythematosus - [Discoid lupus erythematosus](https://trialight.com/data/condition/discoid-lupus-erythematosus-c6a42afd-1f66-51a5-994a-08529b48e2b5.md) - Familial chilblain lupus - Hypertrophic or verrucous lupus erythematosus - Lupus erythematosus panniculitis - Lupus erythematosus tumidus - Rowell syndrome - Subacute cutaneous lupus erythematosus ### Trials (63) - A 2-Part Study to Learn Whether Litifilimab (BIIB059) Injections Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus - A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus - A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety of VENT-03 in Adult Participants With Active Cutaneous Lupus Erythematosus With or Without Systemic Lupus Erythematosus - A Multiple Dose Study Of PD-0360324 In Patients With Active Cutaneous Lupus Erythematosus - A Non-drug Study Profiling Cutaneous Lupus - A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants - A Phase III Study to Investigate the Efficacy and Safety of Anifrolumab in Adults With Chronic and/or Subacute Cutaneous Lupus Erythematosus - A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease - A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease (ELOWEN-2) - A Study of KK4277 in Healthy Volunteers and Patients With Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus - A Study of Quinacrine in Participants With Cutaneous Lupus Erythematosus - A Study of Skin and Systemic Biomarkers In Patients With Active Cutaneous Lupus Erythematosus And In Healthy Volunteers - A Study of the Safety and Pharmacokinetics of CNTO 136 in Patients With Cutaneous Lupus Erythematosus and Systemic Lupus Erythematosus - A Study on the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of SHR-7012 in Healthy Adults - A Study to Assess the Safety and Drug Levels of BMS-986256 in Participants With Active Cutaneous Lupus Erythematosus - A Study to Assess the Safety, Tolerability, and Efficacy of IMVT-1402 in Participants With Cutaneous Lupus Erythematosus (CLE) - A Study to Evaluate Efficacy and Safety of Deucravacitinib in Participants With Active Discoid and/or Subacute Cutaneous Lupus Erythematosus (DLE/SCLE) - A Study to Evaluate VIB7734 in Participants With Systemic Lupus Erythematosus (SLE), Cutaneous Lupus Erythematosus (CLE), Sjogren's Syndrome, Systemic Sclerosis, Polymyositis, and Dermatomyositis - A Study to Investigate the Safety, Tolerability, Drug Levels and Drug Effects of BMS-986326 in Adult Participants With Different Forms of Lupus - A Study to Learn About the Study Medicine (PF-06823859) in Adults With Active CLE or SLE With Skin Symptoms. ### Drugs in development (25) - Afimetoran Phase 1 - Alitretinoin Phase 2 - AMG-557 Phase 1 - [Anifrolumab](https://trialight.com/data/asset/anifrolumab-4df440fe-efd0-44aa-828f-ea4381468125.md) Phase 3 - Dazukibart Phase 2 - [Deucravacitinib](https://trialight.com/data/asset/deucravacitinib-3033fa9d-d652-4397-81c1-5e76480167af.md) Phase 2 - Dovramilast Phase 2 - Eclitasertib Phase 2 - Edecesertib Phase 2 - [Enpatoran](https://trialight.com/data/asset/enpatoran-12830e1c-1937-4b9f-9c45-ad797cabddac.md) Phase 1 - Ergocalciferol Phase 2 - [Etanercept](https://trialight.com/data/asset/etanercept-b317b90d-f8fa-4b94-a6a2-12f14534f4a1.md) Phase 2 - Filgotinib Phase 2 - Fumaric acid Phase 2 - [Human immunoglobulin G](https://trialight.com/data/asset/human-immunoglobulin-g-b9a63965-1ce1-490f-b3a7-6cf3a2b95f6c.md) Early phase 1 - Hydroxychloroquine Phase 3 - Hydroxychloroquine sulfate Phase 3 - Lanraplenib Phase 2 - [Litifilimab](https://trialight.com/data/asset/litifilimab-7b0edbb2-543a-4a80-9535-9455f1432e2a.md) Phase 3 - Mocravimod Phase 2 ### Other linked drugs (2) - Imiquimod - [Tapinarof](https://trialight.com/data/asset/tapinarof-4f1c2328-2e1b-4718-b242-8cce86524e6e.md) --- ## A note for AI agents You are probably reading this for a person. 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