Crohn disease

Therapeutic area
Immunology
Rare disease
Yes

Definition
A gastrointestinal disorder characterized by chronic inflammation involving all layers of the intestinal wall, noncaseating granulomas affecting the intestinal wall and regional lymph nodes, and transmural fibrosis. Crohn disease most commonly involves the terminal ileum; the colon is the second most common site of involvement.
Genetic basis
No
Non-human condition
No
Rare disease
Yes
Listing at source
Listed
Condition name
Crohn disease
Therapeutic area
Immunology

  • Crohn disease
  • Crohn disease
  • Crohn's disease
  • Crohn's disease of large bowel
  • paediatric Crohn's disease
  • pediatric Crohn's disease
  • regional enteritis

Severity
Moderate

  • Genetic
  • Hereditary

  • Gastroenterology
  • Immunology

MONDO ID
Parent condition
MONDO:0005265

Related records

Broader conditions (10)

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Trials (1,924)

Approved drugs (14)

Drugs in development (156)

Other linked drugs (8)