> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/coronary-artery-disorder-6f736849-d477-587a-b3fa-b0621d573407 > Record changed: 2026-10-13 # Coronary artery disorder Therapeutic area Cardiology Rare disease No ## Definition and classification **Definition** Narrowing of the coronary arteries due to fatty deposits inside the arterial walls. The diagnostic criteria may include documented history of any of the following: documented coronary artery stenosis greater than or equal to 50% (by cardiac catheterization or other modality of direct imaging of the coronary arteries); previous coronary artery bypass surgery (CABG); previous percutaneous coronary intervention (PCI); previous myocardial infarction. (ACC) **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Coronary artery disorder **Therapeutic area** Cardiology ### Alternative names (11) - coronary artery disorder - CAD - CHD (coronary heart disease) - coronary artery disease - coronary artery disease or disorder - coronary disease - coronary heart disease - disease of coronary artery - disease or disorder of coronary artery - disorder of coronary artery - coronary arteriosclerosis ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Cardiology - Vascular Medicine ## Identifiers **MONDO ID** MONDO:0005010 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005010) **Parent condition** MONDO:0000473 ## Related records ### Broader conditions (7) - Arterial disorder - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Heart disorder - Human disease - Vascular disorder ### Narrower conditions (25) - Abnormal number of coronary ostia - Anomalous left coronary artery from the pulmonary artery - Aortopulmonary coronary arterial course - Arteriolosclerosis - Arteriosclerosis obliterans - Congenital coronary artery aneurysm - Coronary aneurysm - Coronary arterial fistulas - Coronary artery congenital malformation - Coronary artery disease, autosomal dominant 2 - Coronary artery disease, autosomal dominant, 1 - Coronary artery intramyocardial course - Coronary atherosclerosis - Coronary restenosis - [Coronary stenosis](https://trialight.com/data/condition/coronary-stenosis-4ab5c38e-eee1-50ef-ac96-59608479c153.md) - Coronary thrombosis - Coronary vasospasm - Fibromuscular dysplasia of the coronary arteries - Intermediate coronary syndrome - Intramural coronary arterial course ### Trials (5,952) - "Detection and Follow-up of Coronary Lesions in HeFH (DESTINY-FH Study)" - "Erectile Function After PCI in MI and Non-MI Patients" - "Expert IVUS-Eye" vs. IVUS-guided Left Main Bifurcation PCI - "Immunoregulation in Atherosclerosis: A Single-Cell RNA Sequencing Study" - "JACTAX" Trial Drug Eluting Stent Trial - "L-Sandwich" Strategy in the True Coronary Bifurcation Lesions - "Nutrition Education by Nurses in Patients After Coronary Artery Bypass Grafting: Effect on Patients' Dietary Pattern, Adherence and Clinical Outcomes" - "Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER- - "Potential Effect of Acute and Chronic Caffeine Administration on Platelet Reactivity in Patient With Coronary Artery Disease on Dual Antiplatelet Therapy" - "Preventing Cardiovascular Ischemic Events and Arresting Their Consequences in Type 2 Diabetic Population - "Salvage Use" of Recombinant Factor VIIa After Inadequate Haemostasis in Complex Cardiac Surgery - "The Effect of Virtual Visitation in the Intensive Care Unit on Pain, Anxiety, and Sleep Levels" - "TransRadial Ultra Support Technique" (TRUST) - (A Novel Pharmacologic Regime for Elective Percutaneous Coronary Intervention) - (EASY)-IMProving Adherence to Clopidogrel Trial (IMPACT)) - 1 or 6 Months of Dual Antiplatelet Therapy After Drug-coated Balloon Angioplasty for De-novo Small Coronary Artery Disease - 1-month vs 12-month DAPT for ACS Patients Who Underwent PCI Stratified by IVUS: IVUS-ACS and ULTIMATE-DAPT Trials - 12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe - 123I-BMIPP SPECT Analysis for Decreasing Cardiac Events in Hemodialysis Patients - 123I-mIBG SPECT Imaging ### Approved drugs (24) - [Alirocumab](https://trialight.com/data/asset/alirocumab-94bb5dc8-32f2-4ed6-a82e-b554472e2cd5.md) - Amlodipine besylate - Ammonia N 13 - [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) - Atorvastatin calcium - Bempedoic acid - Dipyridamole - [Evolocumab](https://trialight.com/data/asset/evolocumab-ece543fe-0502-44c3-bef4-ec566503cced.md) - Gemfibrozil - Isosorbide dinitrate - Isosorbide mononitrate - Lovastatin - Niacin - Nitroglycerin - Perindopril erbumine - Pravastatin sodium - Ramipril - [Rivaroxaban](https://trialight.com/data/asset/rivaroxaban-3f354e10-6d35-4989-9e00-318be65808fb.md) - Rosuvastatin calcium - Rubidium chloride RB 82 ### Drugs in development (181) - Acarbose Phase 3 - Acetylcholine Phase 1 - Acetylcysteine Phase 3 - Adenosine Phase 2 - Alanine Phase 3 - Alanyl glutamine Phase 3 - [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md) Phase 3 - Amiloride Phase 2 - Amiodarone Early phase 1 - [Amlodipine](https://trialight.com/data/asset/amlodipine-b06f8f1a-f55d-4a6b-b513-c6443387d4ae.md) Phase 3 - Anacetrapib Phase 3 - Anivamersen Phase 3 - Anpocogin Phase 2 - Apabetalone Phase 3 - Apadenoson Phase 3 - Argatroban Phase 2 - Arginine Phase 1 - Ascorbic acid Phase 3 - Atopaxar Phase 2 - Atorvastatin Phase 3 ### Other linked drugs (21) - Abciximab - Ammonia solution, strong - Antithrombin gamma - Arbutamine - Dabigatran - Darapladib - Fendiline - Iodixanol - Isoproterenol - Maritime pine - [Midazolam](https://trialight.com/data/asset/midazolam-1bd7ce5f-a598-4c40-a36b-e990c47207ef.md) - Montelukast - Omega-3-acid ethyl esters - Omeprazole - Probucol - Regadenoson - Remimazolam - Rubidium RB-82 - Sulfasalazine - Varenicline --- ## A note for AI agents You are probably reading this for a person. 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