> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/colorectal-cancer-09c643cf-146c-5e27-a5b7-3c891b3368c2 > Record changed: 2026-10-13 # Colorectal cancer Therapeutic area Gastroenterology Rare disease Yes ## Definition and classification **Definition** A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma. **Genetic basis** Yes **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Colorectal cancer **Therapeutic area** Gastroenterology ### Alternative names (37) - colorectal cancer - cancer of colorectum - cancer of large bowel - cancer of large intestine - cancer of the large bowel - colon cancer, advanced, somatic - colon cancer, somatic - colorectal cancer - colorectal cancer with chromosomal instability, somatic - colorectal cancer, autosomal dominant, somatic mutation - colorectal cancer, somatic - colorectal cancer, susceptibility to, autosomal dominant, somatic mutation - colorectum cancer - malignant colorectal neoplasm - malignant colorectal tumor - malignant colorectal tumour - malignant colorectum neoplasm - malignant large bowel neoplasm - malignant large bowel tumor - malignant large bowel tumour - malignant large intestine neoplasm - malignant large intestine tumor - malignant large intestine tumour - malignant neoplasm of colorectum - malignant neoplasm of large bowel And 12 more, listed on the interactive page. ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Gastroenterology - Oncology ## Identifiers **MONDO ID** MONDO:0005575 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005575) **Parent condition** MONDO:0005335 ## Related records ### Broader conditions (16) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Colorectal neoplasm](https://trialight.com/data/condition/colorectal-neoplasm-31f0a633-3abe-5df4-9d3a-9292c6541f1d.md) - Digestive system cancer - [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md) - [Digestive system neoplasm](https://trialight.com/data/condition/digestive-system-neoplasm-2ebb9146-1d78-515a-92a3-749515a27d44.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - Intestinal cancer - Intestinal disorder - Intestinal neoplasm - Large intestine disorder - Neoplasm - Neoplastic disease or syndrome ### Narrower conditions (106) - Adenosquamous colon carcinoma - Anal canal adenocarcinoma - Anal canal carcinoma - Anal canal carcinoma in situ - Anal canal neuroendocrine neoplasm - Anal canal Paget disease - Anal canal squamous cell carcinoma - [Anal carcinoma](https://trialight.com/data/condition/anal-carcinoma-d0dca5aa-14ee-5bcc-8bd1-2a2539daa2ec.md) - Anal gland adenocarcinoma - Anal margin basal cell carcinoma - Anal margin carcinoma - Anal margin squamous cell carcinoma - Anal melanoma - Anal mucinous adenocarcinoma - Anal Paget disease - Anal squamous cell carcinoma - Anal verrucous carcinoma - Anus adenocarcinoma - Anus basaloid carcinoma - Anus cancer ### Trials (4,678) - - IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases - ¡Salud! Por la Vida (SPLV) A Colorectal Screening Promotion Program - "Cancersensor" Chemotherapy - "Cancersensor" Metastasis Resection - "Cancersensor": Circadian Rhythms - "High Levels of EMT-TFs for the Diagnosis of Colorectal Cancer (CRC)" - "The Impact of Immunonutrition on Gut Microbiota-related Aspects in Colorectal Cancer and Gastric Cancer Patients" - "Touch 2 Screen" Multi-media Colorectal Cancer Screening Intervention - \[18F\]FLT-PET as a Predictive Imaging Biomaker of Treatment Responses to Regorafenib - \[18F\]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications - \[68Ga\]-NeoBOMB1 Imaging in Patients With Malignancies Known to Overexpress Gastrin Releasing Peptide Receptor (GRPR) - \[68Ga\]BED003 PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications - \[68Ga\]Ga-GZP PET for Early Response Prediction in Colorectal Cancer During Neoadjuvant Therapy - #CuttingCRC: Barbershop-Based Trial & Colorectal Cancer - #iBeatCRC: A Community-based Intervention to Increase Early-onset Colorectal Cancer Awareness - 131-I-TM-601 Study in Adults With Solid Tumors - 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors - 177Lu-J591 Antibody in Patients With Nonprostate Metastatic Solid Tumors - 18F-Fluoroazomycin Arabinoside PET-CT in Diagnosing Solid Tumors in Patients - 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors ### Approved drugs (14) - [Aflibercept](https://trialight.com/data/asset/aflibercept-6bb09e87-ca99-436b-8634-71b90510b8fb.md) - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) - [Cetuximab](https://trialight.com/data/asset/cetuximab-a1f8c65c-bae1-4b77-9491-dca37aeeaa3c.md) - Encorafenib - [Fruquintinib](https://trialight.com/data/asset/fruquintinib-e15c1522-cabe-4f7b-a918-3ca55e1ef88a.md) - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - [Levoleucovorin](https://trialight.com/data/asset/levoleucovorin-fdff57d9-ad4f-4a44-ad7d-40932f268d1b.md) - [Levoleucovorin calcium](https://trialight.com/data/asset/levoleucovorin-calcium-21e918a4-89ff-4c55-aafc-3b4fd0086bc6.md) - [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) - [Panitumumab](https://trialight.com/data/asset/panitumumab-ea8dc0f1-ea1f-4586-b6ad-68fc23ba56f1.md) - [Regorafenib](https://trialight.com/data/asset/regorafenib-333c1c36-b89a-41d5-b39e-bcec7346fe94.md) - [Tipiracil hydrochloride](https://trialight.com/data/asset/tipiracil-hydrochloride-c5072dfa-12fa-4ccc-9e35-c488a67c9673.md) - [Trifluridine](https://trialight.com/data/asset/trifluridine-cf1f965b-3efb-4c26-a766-cb4c7c73675f.md) ### Drugs in development (359) - 6-O-benzylguanine Phase 2 - 7-ethyl-10-hydroxycamptothecin Phase 2 - A33 131I Phase 1 - [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 1 - ABGN-107 Phase 1 - Abituzumab Phase 2 - ABT-751 Phase 2 - [Adagrasib](https://trialight.com/data/asset/adagrasib-550c7524-1104-4d43-9827-298e1041dc2e.md) Phase 1 - [Adebrelimab](https://trialight.com/data/asset/adebrelimab-047820dd-1777-483d-90ab-dd5fc86f78f6.md) Phase 1 - Adecatumumab Phase 2 - Aldesleukin Phase 1 - [Alpelisib](https://trialight.com/data/asset/alpelisib-0b0ae0f7-4313-42ef-bbbe-3280ed5ea15c.md) Phase 2 - AMG-820 Phase 1 - Amifostine Phase 2 - AMP-224 Phase 1 - Anpocogin Phase 2 - Arfolitixorin Phase 3 - Arsenic trioxide Phase 1 - [Artesunate](https://trialight.com/data/asset/artesunate-586f50f5-bb73-43da-8a18-5a2743da577b.md) Phase 2 - Ascorbic acid Phase 3 ### Other linked drugs (15) - Anamorelin hydrochloride - Aprepitant - Atorvastatin - Bempegaldesleukin - Eltanexor - Fosaprepitant - Iohexol - Izorlisib - Ketamine - MGD-007 - Nacolomab tafenatox - Necitumumab - Ropivacaine hydrochloride - Tyrosine - Zenocutuzumab --- ## A note for AI agents You are probably reading this for a person. 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