> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/clear-cell-renal-carcinoma-789eee25-ec64-5771-9b7d-d19544781b11 > Record changed: 2026-10-13 # Clear cell renal carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A malignant epithelial neoplasm of the kidney characterized by the presence of lipid-containing clear cells within a vascular network. The tumor may metastasize to unusual sites and late metastasis is common. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Clear cell renal carcinoma **Therapeutic area** Oncology ### Alternative names (21) - clear cell renal carcinoma - Grawitz tumor - Grawitz tumour - RCC, clear cell adenocarcinoma - clear cell adenocarcinoma of kidney - clear cell adenocarcinoma of the kidney - clear cell adenocarcinoma, kidney - clear cell carcinoma of kidney - clear cell carcinoma of the kidney - clear cell renal cell cancer - clear cell renal cell carcinoma - conventional (clear cell) renal cell adenocarcinoma - conventional (clear cell) renal cell carcinoma - conventional renal cell carcinoma - kidney clear cell adenocarcinoma - kidney clear cell carcinoma - renal cell carcinoma, clear cell adenocarcinoma - renal clear cell adenocarcinoma - renal clear cell carcinoma - clear-cell metastatic renal cell carcinoma - hypernephroma ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Nephrology - Oncology ## Identifiers **MONDO ID** MONDO:0005005 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005005) **Parent condition** MONDO:0005004 ## Related records ### Broader conditions (23) - [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Clear cell adenocarcinoma - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - Glandular cell neoplasm - Human disease - Kidney cancer - [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md) - [Kidney neoplasm](https://trialight.com/data/condition/kidney-neoplasm-6261fea0-4c11-5866-946d-1bb40d83f6e3.md) - Malignant urinary system neoplasm - Neoplasm - Neoplastic disease or syndrome - Nonpapillary renal cell carcinoma - [Renal carcinoma](https://trialight.com/data/condition/renal-carcinoma-133a40e2-e2f7-5921-9086-8e1e5b29f34d.md) - Renal cell adenocarcinoma ### Narrower conditions (2) - Hereditary clear cell renal cell carcinoma - Multilocular clear cell renal cell carcinoma ### Trials (268) - \[18F\] PSMA-1007 PET/CT in Metastatic Clear Cell Renal Cell Carcinoma - \[18F\]PT2385 PET/CT in Patients With Renal Cell Carcinoma - 177LuPSMA in Renal Cell Carcinoma - 18F-T2 PET/CT Imaging for CAIX Positive Solid Tumors - 1st-line Activity of Dovitinib and Correlation With Genetic Changes in RCC - 68Ga-C1 PET/ CT Imaging in Clear Cell Renal Cell Carcinoma - 68Ga-NY104 PET/CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses - 68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC. - 68Ga-NY104 PET/CT in Patients With Metastasis/Recurrence Clear Cell Renal Cell Carcinoma Suspicion - 68Ga-NY104 PET/CT in Patients With Metastatic Clear Cell Renal Cell Carcinoma - 68Ga-NYM096 PET/ CT for the Detection of Clear Cell Renal Cell Carcinoma in Presurgical Patients With Renal Masses - 68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC - 68Ga-P16-093 and 18F-FDG PET/CT Imaging in the Same Group of Clear Cell Renal Cell Carcinoma Patients - 89Zr-DFO-girentuximab Expanded Access Program (EAP) - 89Zr-girentuximab ) Dosimetry in CCRC Study - ZIR-DOSE - 89Zr-TLX250 for PET/CT Imaging of ccRCC - ZIRCON-CP Study - 89Zr-TLX250 for PET/CT Imaging of ccRCC- ZIRCON Study - A Beta-only IL-2 ImmunoTherapY Study - A BIOmarker Driven Trial With Nivolumab and Ipilimumab or VEGFR tKi in Naïve Metastatic Kidney Cancer - A Clinical Research of CD70-targeted CAR-NKT Cells (CGC738) Therapy in RCC ### Approved drugs (13) - Axitinib - [Belzutifan](https://trialight.com/data/asset/belzutifan-2287c89c-8beb-4a1c-a6de-f8d6dfb3499b.md) - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) - Cabozantinib S-malate - [Everolimus](https://trialight.com/data/asset/everolimus-0edf09a9-672d-4f9a-9e34-21ab083a92a4.md) - [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) - [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) - Pazopanib hydrochloride - [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) - Sorafenib tosylate - Sunitinib - Sunitinib malate - Temsirolimus ### Drugs in development (55) - [Abemaciclib](https://trialight.com/data/asset/abemaciclib-602a9f33-bc37-4cf5-8790-5d87472b99d5.md) Phase 1 - Adavosertib Phase 2 - AGS-16C3F Phase 2 - Aldesleukin Phase 3 - Alovudine F-18 Phase 1 - Ascorbic acid Phase 2 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 3 - Batiraxcept Phase 1 - [Cabozantinib](https://trialight.com/data/asset/cabozantinib-e69f9fa7-bbbc-4e52-b0df-6073598de2a7.md) Phase 3 - [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 2 - Camrelizumab Phase 2 - Carotuximab Phase 2 - [Catequentinib](https://trialight.com/data/asset/catequentinib-d03b78d4-b5a5-4756-bbf6-e56f5ec2b7dc.md) Phase 2 - Cediranib maleate Phase 2 - [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 3 - [Daratumumab](https://trialight.com/data/asset/daratumumab-28c327e5-1741-4dd5-89d4-6562e941ab50.md) Early phase 1 - Dovitinib Phase 3 - [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 3 - Entinostat Phase 2 - [Enzalutamide](https://trialight.com/data/asset/enzalutamide-d1214ac0-68e5-4752-9999-977e028ec483.md) Early phase 1 --- ## A note for AI agents You are probably reading this for a person. 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