> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/clear-cell-adenocarcinoma-ccd6cd83-1640-5e88-9e5f-614b2eafccc6 > Record changed: 2026-11-04 # Clear cell adenocarcinoma Therapeutic area Oncology Rare disease No ## Definition and classification **Definition** A malignant neoplasm composed of glandular epithelial clear cells. Various architectural patterns may be seen, including papillary, tubulocystic, and solid. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Clear cell adenocarcinoma **Therapeutic area** Oncology ### Alternative names (6) - clear cell adenocarcinoma - adenocarcinoma, clear cell, malignant - clear cell adenocarcinoma (morphologic abnormality) - clear cell adenocarcinoma NOS (morphologic abnormality) - mesonephroma NOS (morphologic abnormality) - water-clear cell adenocarcinoma (morphologic abnormality) ## Clinical profile **All therapeutic areas** - Oncology Sources for recorded values Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005004) **Severity** Severe ## Identifiers **MONDO ID** MONDO:0005004 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005004) **Parent condition** MONDO:0004970 ## Related records ### Broader conditions (11) - [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - Disease - Disease by etiologic mechanism - Epithelial neoplasm - Glandular cell neoplasm - Human disease - [Neoplasm](https://trialight.com/data/condition/neoplasm-2a973797-359b-5982-907e-98f9b7c1a284.md) - Neoplastic disease or syndrome ### Narrower conditions (20) - Ampulla of vater clear cell adenocarcinoma - Bladder clear cell adenocarcinoma - Bladder diffuse clear cell adenocarcinoma - Bladder papillary clear cell adenocarcinoma - Bladder tubulo-cystic clear cell adenocarcinoma - Cervical clear cell adenocarcinoma - [Clear cell renal carcinoma](https://trialight.com/data/condition/clear-cell-renal-carcinoma-789eee25-ec64-5771-9b7d-d19544781b11.md) - Endometrial clear cell adenocarcinoma - Extrahepatic bile duct clear cell adenocarcinoma - Fallopian tube clear cell adenocarcinoma - Glycogen-rich clear cell breast carcinoma - Hepatocellular clear cell carcinoma - Hereditary clear cell renal cell carcinoma - Hidradenocarcinoma - Multilocular clear cell renal cell carcinoma - Ovarian clear cell adenocarcinoma - Ovarian clear cell cystadenocarcinoma - Urethra clear cell adenocarcinoma - Uterine ligament clear cell adenocarcinoma - Vulvar clear cell hidradenocarcinoma ### Trials (56) - A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer - A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy - A Pilot Study of Celecoxib in Patients With Grade 2 or 3 Uterine Cancers - A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer - A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas - A Study of Nivolumab in Selected Uterine Cancer Patients - [A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers](https://trialight.com/data/trial/a-study-of-safety-and-efficacy-of-kfa115-alone-and-in-combo-6000ed6a-dc09-49ab-af31-2539b9b4fb32.md) - A Study of XmAb20717 (Vudalimab)in Patients With Selected Advanced Gynecologic and Genitourinary Malignancies - A Three-arm Randomized Phase II Study of Dostarlimab Alone or With Bevacizumab Versus Nonplatinum Chemotherapy in Recurrent Gynecological Clear Cell Carcinoma: DOVE (APGOT-OV7/ ENGOT-ov80 Study) - AMT-151 in Patients With Selected Advanced Solid Tumours - An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy - APL-2 and Pembrolizumab Versus APL-2, Pembrolizumab and Bevacizumab Versus Bevacizumab Alone for the Treatment of Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal Cancer and Malignant Effusion - Assessment of Compliance With Monitoring Conducted by a Physician in Person or by a Nurse in Remote Monitoring - Bevacizumab and Intravenous or Intraperitoneal Chemotherapy in Treating Patients With Stage II-III Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer - BrUOG 354 Nivolumab +/- Ipilimumab for Ovarian and Extra-renal Clear Cell Carcinomas - Cabozantinib-S-Malate in Treating Patients With Recurrent or Progressive Ovarian, Fallopian Tube, or Primary Peritoneal Cancer - Carboplatin and Paclitaxel With or Without Bevacizumab in Treating Patients With Stage III or Stage IV Ovarian Epithelial, Primary Peritoneal, or Fallopian Tube Cancer - Carboplatin, Paclitaxel and Gemcitabine Hydrochloride With or Without Bevacizumab After Surgery in Treating Patients With Recurrent Ovarian, Epithelial, Primary Peritoneal, or Fallopian Tube Cancer - Carboplatin, Paclitaxel, Bevacizumab, and Veliparib in Treating Patients With Newly Diagnosed Stage II-IV Ovarian Epithelial, Fallopian Tube, or Primary Peritoneal Cancer - Comparison of Standard of Care Treatment With a Triplet Combination of Targeted Immunotherapeutic Agents ### Drugs in development (14) - [Axitinib](https://trialight.com/data/asset/axitinib-5cec1625-dd7c-4136-ba51-99d1d8d813ec.md) Phase 2 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 2 - [Dostarlimab](https://trialight.com/data/asset/dostarlimab-aad06b17-e988-4591-813f-4b6cef63860f.md) Phase 1 - [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 2 - ENMD-2076 Phase 2 - LB-100 Phase 1 - [Metformin](https://trialight.com/data/asset/metformin-0292cbe3-3a2f-4db7-b783-270ef048c3b4.md) Phase 1 - Metformin hydrochloride Phase 1 - [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) Phase 2 - Risovalisib Phase 2 - [Sintilimab](https://trialight.com/data/asset/sintilimab-e2618eaf-967e-401c-aed4-7546875a6d3e.md) Phase 2 - [Toripalimab](https://trialight.com/data/asset/toripalimab-92e6b353-a6c4-4e1e-a99f-559038ba7177.md) Phase 2 - [Zimberelimab](https://trialight.com/data/asset/zimberelimab-0723178b-0f17-47bf-bdaa-1046f372b9d2.md) Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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