> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/chronic-renal-failure-syndrome-5b98a1aa-2089-59e6-af27-bff008ad07ac
> Record changed: 2026-10-13

# Chronic renal failure syndrome

Therapeutic area

Nephrology

Rare disease

No

## Definition and classification

**Definition**

Impairment of the renal function due to chronic kidney damage.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Chronic renal failure syndrome

**Therapeutic area**

Nephrology

### Alternative names (7)

- chronic renal failure syndrome
- Chronic renal disease
- CRF - chronic renal failure
- chronic kidney failure
- chronic renal failure
- chronic renal failure disease
- kidney failure, chronic

## Clinical profile

**All therapeutic areas**

- Nephrology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0024327

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0024327)

**Parent condition**

MONDO:0001106

## Related records

### Broader conditions (7)

- [Chronic kidney disease](https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918.md)
- Disease
- Disease by body system or component
- Human disease
- [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md)
- [Kidney failure](https://trialight.com/data/condition/kidney-failure-f26737b4-3a55-50be-b6c3-b76514cb5067.md)
- [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md)

### Trials (1,992)

- 123I-BMIPP SPECT Analysis for Decreasing Cardiac Events in Hemodialysis Patients
- 13 Valent Pneumococcal Conjugate Vaccine in Chronic Dialysis Patients
- 16-Week Repeat Oral Dose Study of AKB-6548 for Anemia in Participants With End Stage Renal Disease (ESRD) Requiring Chronic Hemodialysis
- 2% Lidocaine Plus 0.5% Bupivacaine Versus 0.5% Bupivacaine in Brachial Block for Creation of Arteriovenous (AV) Fistula
- 24 Hour Use of the Wearable Artificial Kidney
- A 4-Week Dose-Ranging and Efficacy Trial of KRX-0502 (Ferric Citrate) in Patients With End-Stage Renal Disease
- A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis
- A Clinical Study Comparing Basic Performance and Hemocompatibility of 3 Different Dialyzers in Hemodialysis Patients
- A Clinical Study to Assess the Safety of PEG-Hirudin (SPP200) Compared to Heparin in Patients Who Are on Haemodialysis
- A Clinical Study to Map the HLA Genomic Region in the Greek Population
- A Clinical Trial of Epizon-701 (EPN-701) in Subjects With End-Stage Renal Disease (ESRD)
- A Clinical Trial of IntensiVE Dialysis
- A Clinical Trial of MK-2828 in People With Kidney Disease (MK-2828-006)
- A Cluster-randomized, Pragmatic Trial of Hemodialysis Session Duration
- A Communication Tool to Assist Older Adults Facing Dialysis Choices
- A Comparative Study of Intradialytic vs. Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial
- A Comparison of Dalteparin and Tinzaparin for Prevention of Blood Clots in Hemodialysis Patients on Oral Anticoagulants Having Surgery
- A Comparison of Physical Activity Levels With and Without Feedback Via Fitbit® Flex™ in Hemodialysis Patients
- A Comparison of Propofol Based Total Intravenous Anesthesia and Desflurane Based Balanced Anesthesia on Renal Protection During Deceased Brain Dead Donor Kidney Transplantation - A Prospective, Randomized Trial
- A Cross-Sectional Study to Assess Walking Performance in Subjects With Peripheral Artery and End Stage Kidney Disease

### Approved drugs (6)

- Darbepoetin alfa
- Epoetin alfa
- Epoetin beta
- Folic acid
- Irbesartan
- Lanthanum carbonate

### Drugs in development (59)

- Acetylcysteine Phase 3
- Adomeglivant Phase 1
- Alemtuzumab Phase 2
- Alisporivir Phase 1
- Angiotensin Phase 3
- Apabetalone Phase 1
- [Balcinrenone](https://trialight.com/data/asset/balcinrenone-039aff61-faf5-4267-bfc5-f89dce767007.md) Phase 2
- [Belatacept](https://trialight.com/data/asset/belatacept-8e93aa79-7b65-4b31-b315-47488d14be9d.md) Phase 3
- Carvedilol Phase 3
- Cinacalcet Phase 3
- Clopidogrel Phase 3
- [Cyclophosphamide](https://trialight.com/data/asset/cyclophosphamide-25b75968-e3cd-410a-9b24-0c349d8f7663.md) Phase 2
- Cyclosporine Phase 3
- Daclizumab Phase 3
- Dalteparin sodium Phase 3
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md) Phase 3
- Desidustat Phase 3
- [Dexamethasone](https://trialight.com/data/asset/dexamethasone-b923ddae-f095-408c-96e9-975238a429ad.md) Phase 3
- Dextrose Phase 3
- Efalizumab Phase 1

### Other linked drugs (9)

- Benazepril
- Bixalomer
- Epoetin theta
- Epoetin zeta
- Methoxy polyethylene glycol-epoetin beta
- Phenacetin
- Physioneal
- Tacrolimus
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md)

---

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