> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/chronic-kidney-disease-dc1fecbb-338b-5bbc-8d68-08e49db49918
> Record changed: 2026-10-13

# Chronic kidney disease

Therapeutic area

Nephrology

Rare disease

No

## Definition and classification

**Definition**

Impairment of the renal function secondary to chronic kidney damage persisting for three or more months.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Chronic kidney disease

**Therapeutic area**

Nephrology

### Alternative names (6)

- chronic kidney disease
- CKD - chronic kidney disease
- chronic kidney disease
- chronic renal disease
- kidney disease, chronic
- chronic renal failure syndrome

## Clinical profile

**All therapeutic areas**

- Nephrology

**Severity**

Severe

## Identifiers

**MONDO ID**

MONDO:0005300

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005300)

**Parent condition**

MONDO:0005240

## Related records

### Broader conditions (5)

- Disease
- Disease by body system or component
- Human disease
- [Kidney disorder](https://trialight.com/data/condition/kidney-disorder-e50371fe-f1a7-53fe-9cfb-9d6da9130e3c.md)
- [Urinary system disorder](https://trialight.com/data/condition/urinary-system-disorder-68e8d758-aac9-544b-8378-87fe59b2c7b0.md)

### Narrower conditions (7)

- Arterionephrosclerosis
- Chronic pyelonephritis
- Chronic rapidly progressive glomerulonephritis
- [Chronic renal failure syndrome](https://trialight.com/data/condition/chronic-renal-failure-syndrome-5b98a1aa-2089-59e6-af27-bff008ad07ac.md)
- [Diabetic kidney disease](https://trialight.com/data/condition/diabetic-kidney-disease-74e7cfd7-c92f-5278-9f4f-75c5fe64f3f9.md)
- End stage renal failure
- Xanthogranulomatous pyelonephritis

### Trials (2,256)

- "Hypoxic vs. Aerobic Training in Chronic Kidney Disease
- "Residual Kidney Function and Oxidative Stress in Incremental vs Standard Peritoneal Dialysis (2 Mexican Centers)"
- 12 Weeks of Hemodialysis With Medium Cut-Off Filter Compared to Hemodiafiltration With Standard High-flux Filter.
- 20-Week Repeat Oral Dose Study of AKB-6548 in Participants With Chronic Kidney Disease and Anemia
- 20070360 Incident Dialysis
- 24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease
- 2D-speckle Tracking in Pediatric Renal Chronic Disease
- 4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis
- A Biomarker-targeted Clinical Trial to Optimize Treatment for Patients With Chronic Kidney Disease
- A Cardiometabolic Health Program Linked With Clinical-Community Support and Mobile Health Telemonitoring to Reduce Health Disparities
- A Chronic Care Model Based Quality Improvement (QI) Program to Improve the Care of Patients With Chronic Kidney Disease (CKD)
- A Clinical Study to Evaluate the Pharmacokinetics of Microdose Midazolam, Dabigatran, Pitavastatin, Atorvastatin and Rosuvastatin in Healthy Volunteers and Renal Impairment Patients
- A Clinical Study to Evaluate the Safety, Tolerability and Activity of a New Phosphate Binder (SBR759) in Patients With Chronic Kidney Disease on Hemodialysis
- A Clinical Trial of Oral Versus IV Iron in Patients With Chronic Kidney Disease
- A Clinical Trial to Define the Best Strategy for the Management of Heart Failure in Elderly Patients
- A Cluster Randomized Trial to Assess the Impact of Patient and Provider Education on Use of Home Dialysis
- A Cohort Study on the Integrated Management of Chronic Kidney Disease
- A Communication-Priming Intervention to Improve Shared Decision-Making Between Older Adults With Advanced CKD and Clinicians
- A Comparative Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis
- A Comparative Study of Intradialytic vs. Pre-Dialysis Physical Therapy Interventions in Individuals Undergoing Hemodialysis: A Randomized Controlled Trial

### Approved drugs (48)

- Ascorbic acid
- Biotin
- Calcifediol
- Calcitriol
- Calcium acetate
- Ceftaroline fosamil acetate
- Chlorothiazide
- Chlorthalidone
- Cinacalcet hydrochloride
- Cyanocobalamin
- [Dapagliflozin](https://trialight.com/data/asset/dapagliflozin-894f296e-52de-4036-ac69-f399eea07356.md)
- Dapagliflozin propanediol
- Daprodustat
- Darbepoetin alfa
- Difelikefalin acetate
- Doxercalciferol
- [Empagliflozin](https://trialight.com/data/asset/empagliflozin-09301932-ac0f-4eb7-8d1d-bd13fdbb6ab8.md)
- Epoetin alfa
- Epoetin beta
- Epoetin delta

### Drugs in development (204)

- Acetylcysteine Phase 3
- [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 2
- Aliskiren Phase 1
- Allopurinol Phase 2
- Amisulpride Phase 1
- [Anakinra](https://trialight.com/data/asset/anakinra-2c0352ee-cb20-46c5-bd87-6350d9024e75.md) Phase 2
- [Apixaban](https://trialight.com/data/asset/apixaban-9e91f03a-6eac-4da8-9f08-88d740399be5.md) Phase 2
- [Aspirin](https://trialight.com/data/asset/aspirin-03870fc6-137e-47aa-9f14-b7ae6754fb15.md) Phase 3
- Atorvastatin Phase 3
- Atorvastatin calcium Phase 3
- Atrasentan Phase 2
- [Atuliflapon](https://trialight.com/data/asset/atuliflapon-850ef0c1-21fa-44ee-bad0-082cfb01dd83.md) Phase 2
- AUS-131 Phase 2
- Avacopan Phase 1
- Avenciguat Phase 2
- Azathioprine Phase 3
- [Balcinrenone](https://trialight.com/data/asset/balcinrenone-039aff61-faf5-4267-bfc5-f89dce767007.md) Phase 2
- Bardoxolone methyl Phase 2
- [Baricitinib](https://trialight.com/data/asset/baricitinib-dde0cdc5-8f75-41b1-bc92-b187471c63df.md) Phase 2
- Basiliximab Phase 2

### Other linked drugs (20)

- [Alteplase](https://trialight.com/data/asset/alteplase-89461f67-4f40-4a00-ae4c-727752018887.md)
- Amino acids
- Benazepril
- Bixalomer
- Domperidone
- Fepixnebart
- [Insulin glargine](https://trialight.com/data/asset/insulin-glargine-8aa23d8d-fb05-42b5-b490-2e4b67136155.md)
- Inulin
- Inuline
- Lactulose
- Lorazepam
- Montelukast
- Nitroglycerin
- Phenacetin
- Physioneal
- Ropivacaine
- Tacrolimus
- Tamsulosin
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md)
- Vonsetamig

---

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