> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/chronic-hepatitis-c-virus-infection-418264a5-feb7-5845-9b0b-33ec34544fbf
> Record changed: 2026-10-13

# Chronic hepatitis C virus infection

Therapeutic area

Gastroenterology

Rare disease

No

## Definition and classification

**Definition**

Chronic form of hepatitis C infection.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Chronic hepatitis C virus infection

**Therapeutic area**

Gastroenterology

### Alternative names (4)

- chronic hepatitis C virus infection
- chronic Hepatitis C
- hepatitis C infection, chronic
- hepatitis C, chronic

## Clinical profile

**Severity**

Moderate

### Disease mechanisms (2)

- Acquired
- Inflammatory

### All therapeutic areas (3)

- Endocrinology
- Gastroenterology
- Infectious Disease

## Identifiers

**MONDO ID**

MONDO:0005354

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005354)

**Parent condition**

MONDO:0005231

## Related records

### Broader conditions (18)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Digestive system infectious disorder
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- [Hepatitis](https://trialight.com/data/condition/hepatitis-6b771058-c7ad-5a5f-aa35-ea69998a764a.md)
- Hepatitis C virus infection
- Hepatobiliary disorder
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Inflammatory disease
- [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md)
- Primary viral infectious disease
- Viral hepatitis
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md)

### Trials (1,046)

- 'Fibrosis in the Lost Hepatitis C Population - Track, Trace and Treat'
- "Real Life" Evaluation of Efficacy and Safety of Direct Antiviral Agents (DAAs) for the Treatment of Hepatitis C Virus in Egypt
- 100% VS 80% Of Pegasys In Koreans With Chronic Hepatitis C (CHC)
- 24 VS 48-WEEK TREATMENT WITH PEG-IFN ALPHA-2A IN PATIENTS WITH GENOTYPE 2/3 CHRONIC HEPATITIS C
- 3-year Follow-up Study to Assess the Viral Activity in Hepatitis C Patients Who Failed Feeder DEB025/Alisporivir Study
- 4 Week Combination of BI 207127 NA With Peg-IFN and Ribavirin in Chronic HCV Patients
- 4-Methylumbelliferone as a Treatment for Chronic HBV/HCV
- 4-Week Lead-In With Nitazoxanide Followed by 36 Weeks Nitazoxanide and Peginterferon Alfa-2a in Chronic Hepatitis C
- 480 STUDY: Phase 2b Study of Locteron Plus Ribavirin to Treat Hepatitis C Virus (HCV)
- 5 Year Long-term Follow up in Pediatric Participants Who Received PegIntron Plus Rebetol in P02538 Part I (P02538 Pt 2)
- 8 Weeks Versus 12 Weeks of Elbasvir/Grazoprevir in Treatment-naïve CHC With Mild Fibrosis
- A Caspase Inhibitor in Chronic Hepatitis C (HCV) Patients
- A Clinical Trial of 16 Weeks of Duration to Evaluate Retreatment With Elbasvir/Grazoprevir Plus Sofosbuvir and Ribavirin in Patients With Chronic Hepatitis C Genotypes 1,4 Who Have Failed to Treat With a Regime Based on an Inhibitor of the NS5A
- A Collaborative Trial in Injectors of Individualized Treatment for Genotype 2/3
- A Comparison of the Effectiveness, Safety, and Tolerability of Two Different Hepatitis C Treatments in Patients Infected With Both HIV and Hepatitis C Virus (HCV)
- A Drug-Drug Interaction Study Evaluating the Combination of IDX320 and IDX184 in Healthy Participants (MK-6844-002)
- A First Time in Human Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single & Repeat Escalating Doses of GSK2878175 in Healthy Subjects
- A Follow up Study Designed to Obtain Long Term Data on Participants Who Either Achieved a Sustained Virologic Response or Did Not Achieve a Sustained Virologic Response in an AbbVie Sponsored Hepatitis C Study
- A Gilead Sequence Registry of Subjects Who Did Not Achieve Sustained Virologic Response
- A Multicenter Treatment Protocol of Daclatasvir (BMS-790052) in Combination With Sofosbuvir for the Treatment of Post-Liver Transplant Subjects With Chronic Hepatitis C

### Approved drugs (23)

- Boceprevir
- Daclatasvir dihydrochloride
- Dasabuvir sodium monohydrate
- Elbasvir
- Eltrombopag choline
- Eltrombopag olamine
- Glecaprevir
- Grazoprevir anhydrous
- Interferon alfa-2B
- Interferon alfacon-1
- Ledipasvir
- Ombitasvir
- Paritaprevir
- [Peginterferon alfa-2A](https://trialight.com/data/asset/peginterferon-alfa-2a-30150acd-a3d1-4c13-9915-fc321ebfd6ba.md)
- [Peginterferon alfa-2B](https://trialight.com/data/asset/peginterferon-alfa-2b-7a0d9927-e591-4a99-9c41-725b8a7a41a7.md)
- Pibrentasvir
- [Ribavirin](https://trialight.com/data/asset/ribavirin-94510534-209a-4906-917e-ae8c153df440.md)
- [Ritonavir](https://trialight.com/data/asset/ritonavir-8662f393-091d-46b9-87cc-73f29dca2219.md)
- Simeprevir sodium
- [Sofosbuvir](https://trialight.com/data/asset/sofosbuvir-0299363f-7b98-4f5e-ad74-2373e14d1d7b.md)

### Drugs in development (106)

- ABT-072 Phase 2
- Adafosbuvir Phase 2
- Albinterferon alfa-2B Phase 3
- Alisporivir Phase 3
- Amantadine Phase 3
- Asunaprevir Phase 3
- Balapiravir Phase 2
- Baminercept Phase 1
- Beclabuvir Phase 2
- Bemnifosbuvir sulfate Phase 2
- Betaine Early phase 1
- BILB-1941 Phase 1
- BMS-929075 Phase 1
- Bulevirtide Phase 3
- Caffeine Phase 1
- Celgosivir Phase 2
- Chlorcyclizine hydrochloride Phase 1
- [Colchicine](https://trialight.com/data/asset/colchicine-ae804b3e-3263-453f-abb3-ae1e813f2ccf.md) Phase 2
- CTS-1027 Phase 2
- Cyclosporine Phase 3

### Other linked drugs (3)

- Grazoprevir
- Norucholic acid
- Taurursodiol

---

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