> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/chronic-hepatitis-b-virus-infection-f0c75c88-745f-5098-8240-0ee9c839439b
> Record changed: 2026-10-13

# Chronic hepatitis B virus infection

Therapeutic area

Gastroenterology

Rare disease

No

## Definition and classification

**Definition**

Chronic form of hepatitis B infection.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

No

**Listing at source**

Listed

**Condition name**

Chronic hepatitis B virus infection

**Therapeutic area**

Gastroenterology

### Alternative names (4)

- chronic hepatitis B virus infection
- chronic Hepatitis B
- hepatitis B infection, chronic
- hepatitis B, chronic

## Clinical profile

**Severity**

Severe

### Disease mechanisms (2)

- Acquired
- Inflammatory

### All therapeutic areas (3)

- Endocrinology
- Gastroenterology
- Infectious Disease

## Identifiers

**MONDO ID**

MONDO:0005366

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005366)

**Parent condition**

MONDO:0005344

## Related records

### Broader conditions (19)

- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Digestive system infectious disorder
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- [Endocrine system disorder](https://trialight.com/data/condition/endocrine-system-disorder-7bab6998-7c2b-586b-940e-d8d567288d52.md)
- Hepadnaviridae infectious disease
- [Hepatitis](https://trialight.com/data/condition/hepatitis-6b771058-c7ad-5a5f-aa35-ea69998a764a.md)
- [Hepatitis B virus infection](https://trialight.com/data/condition/hepatitis-b-virus-infection-63cb6d13-50c4-5e97-86fd-ce5481d9d1c6.md)
- Hepatobiliary disorder
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Inflammatory disease
- [Liver disorder](https://trialight.com/data/condition/liver-disorder-8388d30a-2581-5015-9ddf-adc5f6a331d7.md)
- Primary viral infectious disease
- Viral hepatitis
- [Viral infectious disease](https://trialight.com/data/condition/viral-infectious-disease-43db42a3-adad-5b9d-b74c-f17df0674c21.md)

### Trials (856)

- "Real-life" Cohort Study on Patients With Chronic HBV Infection in Jiangsu
- 3E Extension Study
- 4-Methylumbelliferone as a Treatment for Chronic HBV/HCV
- A 2 PART STUDY EVALUATING EDP-721 IN HEALTHY SUBJECTS AND EDP-721 IN COMBINATION WITH EDP-514 IN PATIENTS WITH CHRONIC HEPATITIS B VIRUS INFECTION.
- A Clinical Evaluation on Traditional Chinese Medicine Diagnosis and Treatment Program Blocking and Reversing Hepatitis B-related Liver Fibrosis - a Randomized, Controlled, Double-blind, Multi-center Clinical Trial
- A Clinical Research on Disease Progression and Intervention of Chronic HepatitisB
- A Clinical Study Evaluating the Pharmacokinetic Characteristics and Safety of AHB-137 Injection in Participants With Mild to Moderate Liver Dysfunction and Those With Normal Liver Function.
- A Clinical Study of 162 in Subjects With Chronic Hepatitis B Virus Infection
- A Clinical Study of APG-1387 in Combination With Entecavir in Patients With Chronic Hepatitis B
- A Clinical Study of HH-006 in Untreated Chronic Hepatitis B Virus Infected Patients
- A Clinical Study of HT-101 and HT-102 in Patients With Chronic Hepatitis B Virus Infection
- A Clinical Study of HT-101 and/or HT-102 in Patients With Chronic Hepatitis B Virus Infection
- A Clinical Study of TQA3605 Tablets Monotherapy or in Combination With Nucleoside (Acid) Analogues in Treatment Naive and Treated Patients With Chronic Hepatitis B
- A Clinical Study to Evaluate the Efficacy of TQA3038 Injection in Patients With Chronic Hepatitis B
- A Clinical Trial of TQA3038 Injection in Healthy Adult Subjects
- A Clinical Trial on HB-Vac Activated-DCs Combined With Peg-IFN or NAs in CHB
- A Clinical Trial on Hepatitis B Vaccine Activated-Dendritic Cells Combined With Anti-HBV Drugs in CHB
- A Clinical Trial to Evaluate the Efficacy and Safety of TQA3605 Tablets in Treatment-naive Chronic HBV-infected Subjects
- A Clinical Trial to Evaluate the Efficacy and Safety of TQA3810 Tablets in Combination/Non Combination With Nucleoside (Acid) Analogues in Patients With Primary/Treated Chronic Hepatitis B
- A Clinical Trials to Evaluate the Efficacy and Safety of Tenofovir With and Without DWPUR001 in Patients With HBV

### Approved drugs (10)

- Adefovir dipivoxil
- [Entecavir](https://trialight.com/data/asset/entecavir-4df4be16-2f66-48e2-810c-24457b3f43fc.md)
- Hepatitis B immune globulin
- [Hepatitis B virus hbsag surface protein antigen](https://trialight.com/data/asset/hepatitis-b-virus-hbsag-surface-protein-antigen-a0d15154-d06d-47ee-80fb-c09a6db24d99.md)
- Interferon alfa-2B
- Lamivudine
- [Peginterferon alfa-2A](https://trialight.com/data/asset/peginterferon-alfa-2a-30150acd-a3d1-4c13-9915-fc321ebfd6ba.md)
- [Telbivudine](https://trialight.com/data/asset/telbivudine-5718dabe-4058-4559-b924-29d47b6e47ed.md)
- [Tenofovir alafenamide fumarate](https://trialight.com/data/asset/tenofovir-alafenamide-fumarate-9adf6f5f-c34a-4fdb-9c9f-210ec050ca0b.md)
- [Tenofovir disoproxil fumarate](https://trialight.com/data/asset/tenofovir-disoproxil-fumarate-a85e5cf5-74a5-4f7d-a323-e43ff7caf12b.md)

### Drugs in development (67)

- AB-101 Phase 1
- Adefovir Phase 3
- Albinterferon alfa-2B Phase 1
- Antroquinonol Phase 2
- APG-1387 Phase 2
- Bepirovirsen Phase 3
- Bersacapavir Phase 2
- Besifovir Phase 3
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 2
- [Cetrelimab](https://trialight.com/data/asset/cetrelimab-3efc0fa4-bffb-4b48-bdc8-d69f58f2bb03.md) Phase 1
- Chlorpheniramine Phase 2
- Clevudine Phase 3
- [Daunorubicin](https://trialight.com/data/asset/daunorubicin-903e3e75-4637-461c-9ca8-608fdf707576.md) Phase 3
- Diammonium glycyrrhizinate Phase 3
- [Digoxin](https://trialight.com/data/asset/digoxin-9928e38a-813e-4948-9d65-9088ba40a442.md) Phase 1
- Diphenhydramine Phase 2
- [Durvalumab](https://trialight.com/data/asset/durvalumab-bca7c265-7862-46e1-bf29-3dd2fdda4954.md) Phase 2
- [Elebsiran](https://trialight.com/data/asset/elebsiran-893e640f-f650-4daf-b2d8-62bfaf8c13d0.md) Phase 2
- Elvucitabine Phase 2
- [Emtricitabine](https://trialight.com/data/asset/emtricitabine-96c159c1-a754-4dde-82ba-535afdc1dfa1.md) Phase 3

### Other linked drugs (3)

- Interferon
- Metformin
- [Prednisone](https://trialight.com/data/asset/prednisone-a5a99f90-5fbe-45c2-a625-34ba78735da6.md)

---

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