> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/chronic-bronchitis-1182c6a7-3657-5c56-89e7-6c969a2220da > Record changed: 2026-10-13 # Chronic bronchitis Therapeutic area Pulmonology Rare disease No ## Definition and classification **Definition** A type of chronic obstructive pulmonary disease characterized by chronic inflammation in the bronchial tree that results in edema, mucus production, obstruction, and reduced airflow to and from the lung alveoli. The most common cause is tobacco smoking. Signs and symptoms include coughing with excessive mucus production, and shortness of breath. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Chronic bronchitis **Therapeutic area** Pulmonology ### Alternative names (2) - chronic bronchitis - bronchitis, chronic ## Clinical profile **Disease mechanisms** - Inflammatory **All therapeutic areas** - Pulmonology **Severity** Moderate ## Identifiers **MONDO ID** MONDO:0005607 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005607) **Parent condition** MONDO:0003781 ## Related records ### Broader conditions (15) - [Bronchial disorder](https://trialight.com/data/condition/bronchial-disorder-86634eee-9f2b-5ce7-9dab-75b548e41ff7.md) - [Bronchitis](https://trialight.com/data/condition/bronchitis-521c8a00-6a48-5246-b908-ec54f125daf0.md) - [Chronic obstructive pulmonary disease](https://trialight.com/data/condition/chronic-obstructive-pulmonary-disease-8e23f74b-95b9-5920-a241-c0278555234f.md) - Disease - Disease by body system or component - Disease by developmental or physiological process - Human disease - Inflammatory disease - [Lower respiratory tract disorder](https://trialight.com/data/condition/lower-respiratory-tract-disorder-cfa96f5e-8af8-555b-a663-55befbd68962.md) - [Lung disorder](https://trialight.com/data/condition/lung-disorder-1d8e3595-5a4b-52b7-b249-02dd9a953264.md) - Obstructive lung disease - Respiratory system disorder - Tracheal disorder - Tracheobronchitis - Upper respiratory tract disorder ### Trials (200) - 28-day Repeat Dose Study of GSK573719 - 7 Days of TD-4208 in Subjects With Chronic Obstructive Pulmonary Disease - A 52-week, Placebo- and Active- Controlled (Roflumilast, Daliresp® 500µg) Study to Evaluate the Efficacy and Safety of Two Doses of CHF6001 DPI (Tanimilast) as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis. (PILLAR) - A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER) - A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD - A Clinical Evaluation of the RheOx Bronchial Rheoplasty System - A Comparison Study of Two Respiratory Physical Therapy Methods and Standard Medical Treatment for Treating COPD Patients During Acute Exacerbation - A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China - A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Acute Symptoms of Chronic Bronchitis - A Multicentre, Randomised, Open-Label Study To Compare The Efficacy And Safety Of Azithromycin For 5 Days With Those Of Amoxicillin-Clavulanic Acid In Patients With Chronic Bronchitis - A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis - A Pilot Study to Evaluate the ROX Anastomotic Coupler System in Patients With Chronic Obstructive Pulmonary Disease - A Randomized, Double Blind, Placebo Controlled, Incomplete Block, Crossover, Dose Ranging Study to Evaluate the Dose Response of GSK573719 Administered Once or Twice Daily Over 7 Days in Patients With Chronic Obstructive Pulmonary Disease (COPD) - A Safety, Tolerability and Efficacy Study With QBW251 in COPD Patients With QBW251 - [A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Study Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD) With Chronic Bronchitis](https://trialight.com/data/trial/a-study-of-24-to-52-weeks-treatment-to-evaluate-the-efficacy-bbbc2853-15c7-4790-8548-7fe140353e29.md) - A Study of Arformoterol Tartrate Inhalation Solution and Tiotropium Bromide on Re-hospitalization in Chronic Obstructive Pulmonary Disease (COPD) Subjects - [A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)](https://trialight.com/data/trial/a-study-of-brenipatide-ly3537031-in-adult-participants-with-62296ecc-0ea5-4432-97e0-51148f316213.md) - A Study of the Effectiveness and Safety of High Dose, Short-course Levofloxacin in the Treatment of Acute Bacterial Exacerbation (Worsening) of Chronic Bronchitis. - A Study of the Safety and Effectiveness of Levofloxacin Compared With Cefaclor in the Treatment of Adults With Chronic Bronchitis Experiencing Rapid Onset of Worsening of Symptoms Caused by Bacteria - A Study of the Safety and Effectiveness of Oral Levofloxacin Compared With Cefuroxime Axetil in the Treatment of Adults With Persistent Bronchitis Experiencing Rapid Onset of Severe Worsening of Symptoms Caused by Bacteria ### Approved drugs (29) - Aclidinium bromide - Arformoterol tartrate - Azithromycin - [Budesonide](https://trialight.com/data/asset/budesonide-15e6ba7b-3021-46e9-b180-bf23025bbc67.md) - Cefaclor - Cefdinir - Cefditoren pivoxil - Cefixime - Cefprozil, (E)- - Ceftibuten dihydrate - Cefuroxime axetil - Ciprofloxacin - Clarithromycin - Fluticasone propionate - [Formoterol fumarate](https://trialight.com/data/asset/formoterol-fumarate-235f1f49-5d38-4e21-b612-da2d6d446b33.md) - [Glycopyrronium bromide](https://trialight.com/data/asset/glycopyrronium-bromide-3e811428-27d6-4276-96b9-b0b17847e0e3.md) - Indacaterol maleate - Ipratropium bromide - Levofloxacin - [Moxifloxacin hydrochloride](https://trialight.com/data/asset/moxifloxacin-hydrochloride-4ece6ff8-05f0-4c28-bc77-7234f29c553b.md) ### Drugs in development (14) - ABX-IL8 Phase 2 - Acetylcysteine Phase 2 - [Amoxicillin](https://trialight.com/data/asset/amoxicillin-09050e6a-69b4-42d1-b3eb-79212edcf388.md) Phase 3 - Arformoterol Phase 3 - Clavulanic acid Phase 3 - Cofirasersen Phase 2 - Erdosteine Phase 2 - Faropenem medoxomil Phase 3 - Ivacaftor Phase 2 - [Moxifloxacin](https://trialight.com/data/asset/moxifloxacin-17fc41bd-6b29-4dda-a755-554e6ce94ccc.md) Phase 3 - Prulifloxacin Phase 3 - [Salmeterol](https://trialight.com/data/asset/salmeterol-97bdfb51-b314-47e7-9755-5174e2c52203.md) Phase 3 - Tiotropium Early phase 1 - [Tozorakimab](https://trialight.com/data/asset/tozorakimab-2f585124-3232-4184-a7a4-ad2b7db2f5dd.md) Phase 2 ### Other linked drugs (2) - Ceftibuten - Grepafloxacin --- ## A note for AI agents You are probably reading this for a person. 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