> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/cholera-89395c52-b4b6-5929-ae68-d4505e355182
> Record changed: 2026-11-04

# Cholera

Therapeutic area

Gastroenterology

Rare disease

Yes

## Definition and classification

**Definition**

Cholera is an infectious disease, caused by intestinal infection with Vibrio cholerae, characterized by massive watery diarrhea and severe dehydration that can lead to shock and death if left untreated.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Cholera

**Therapeutic area**

Gastroenterology

### Alternative names (7)

- cholera
- Cholera (Disorder)
- cholera due to Vibrio cholerae
- Vibrio cholerae caused disease or disorder
- Vibrio cholerae disease or disorder
- Vibrio Cholerae Infection
- Vibrio cholerae infectious disease

## Clinical profile

**Severity**

Severe

### Disease mechanisms (2)

- Acquired
- Inflammatory

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015766)

### All therapeutic areas (2)

- Gastroenterology
- Infectious Disease

Sources for recorded values

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015766)

## Identifiers

**MONDO ID**

MONDO:0015766

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0015766)

**Parent condition**

MONDO:0000314

## Related records

### Broader conditions (18)

- [Bacterial infectious disease](https://trialight.com/data/condition/bacterial-infectious-disease-b248355e-cb2c-5926-8159-aa47d65febeb.md)
- [Digestive system disorder](https://trialight.com/data/condition/digestive-system-disorder-ae55641c-32fa-5aa9-ab90-29f763a95dc0.md)
- Digestive system infectious disorder
- Disease
- Disease by body system or component
- Disease by developmental or physiological process
- Disease by etiologic mechanism
- Disease of primarily extrinsic mechanism
- [Gastroenteritis](https://trialight.com/data/condition/gastroenteritis-6f158f22-dfd3-577b-847d-64d9cf80af87.md)
- Gastrointestinal mucositis
- Human disease
- [Infectious disease](https://trialight.com/data/condition/infectious-disease-dadc2591-65fc-5842-b510-cfbc295d8093.md)
- Inflammatory disease
- Intestinal disorder
- Intestinal infectious disease
- Mucositis
- Primary bacterial infectious disease
- Vibrio infectious disease

### Trials (77)

- A Phase 3 Lot to Lot Consistency Study of Live Oral Cholera Vaccine, PXVX0200 in Healthy Adults
- [A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131).](https://trialight.com/data/trial/a-phase-iii-randomized-modified-double-blind-multi-centric-bf57c8d0-ed8a-4721-9c1a-6d3cdc7c28dd.md)
- A Study of Live Oral Cholera Vaccine, PXVX200 in Healthy Older Adults
- A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in Dominican Republic
- A Study of Two Doses of Oral Cholera Vaccine (Shanchol™) in Subjects Aged 1 Year and Older in the Philippines
- A Study to Evaluate Safety and Immunogenicity of the Bivalent Killed Whole Cell Oral Cholera Vaccine in Adults and Children
- Assessment of a Novel Fixed-dose Combination (FDC) Drug VR-AD-1005 for the Treatment of Acute Watery Diarrhea in Cholera
- Bridging Study for Killed Oral Cholera Vaccine in Ethiopia
- Cholera Anti-Secretory Treatment Trial
- Cholera Control by Case-area Targeted Interventions (CATIs)
- Cholera Vaccine Investment Strategy in Bangladesh
- Cholera-Hospital-Based-Intervention-for-7-days
- Cholera-Hospital-Based-Intervention-for-7-Days (CHoBI7) Water, Sanitation, and Hygiene (WASH) Case Area Targeted Intervention (CATI)
- Ciprofloxacin Multiple Dose for Adult Cholera
- Co-administration Study of OCV, TCV and MR
- Effect of Extended Dose Intervals on the Immune Response to Oral Cholera Vaccine
- Effect of Probiotic on Immunogenicity of Oral Cholera Vaccine
- Effectiveness of a Bivalent Killed Whole Cell Based Oral Cholera Vaccine
- Efficacy of Benefiber-Added, Reduced-Osmolarity WHO-ORS in the Treatment of Cholera in Adults
- Efficacy of iOWH032 in Dehydrating Cholera

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