> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/cervical-squamous-cell-carcinoma-cf19f5cb-f41b-58a1-a675-3d881c3a62a2 > Record changed: 2026-10-13 # Cervical squamous cell carcinoma Therapeutic area Oncology Rare disease Yes ## Definition and classification **Definition** A squamous cell carcinoma arising from the cervical epithelium. It usually evolves from a precancerous cervical lesion. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors for cervical squamous cell carcinoma. The following histologic patterns have been described: conventional squamous cell carcinoma, papillary squamous cell carcinoma, transitional cell carcinoma, lymphoepithelioma-like carcinoma, verrucous carcinoma, condylomatous carcinoma and spindle cell carcinoma. Survival is most closely related to the stage of disease at the time of diagnosis. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Cervical squamous cell carcinoma **Therapeutic area** Oncology ### Alternative names (14) - cervical squamous cell carcinoma - cervical squamous cell cancer - cervical squamous cell carcinoma - cervix squamous cell carcinoma - cervix uteri squamous cell carcinoma - squamous cell carcinoma of cervix - squamous cell carcinoma of cervix uteri - squamous cell carcinoma of the cervix - squamous cell carcinoma of the cervix uteri - squamous cell carcinoma of the uterine cervix - squamous cell carcinoma of uterine cervix - squamous cervical cancer - uterine cervix squamous cell carcinoma - CESC ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Oncology - Reproductive Health ## Identifiers **MONDO ID** MONDO:0006143 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006143) **Parent condition** MONDO:0005096 ## Related records ### Broader conditions (26) - [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md) - Cancer or benign tumor - [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md) - [Cervical cancer](https://trialight.com/data/condition/cervical-cancer-10fb8f6c-5aac-5281-8f06-7238adeec443.md) - Cervical carcinoma - Cervix disorder - Disease - Disease by body system or component - Disease by etiologic mechanism - [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md) - [Female reproductive organ cancer](https://trialight.com/data/condition/female-reproductive-organ-cancer-1207d84e-931f-51b6-90d9-6b2135cdebbb.md) - Female reproductive system disorder - Female reproductive system neoplasm - Human disease - Neoplasm - Neoplastic disease or syndrome - Reproductive system cancer - Reproductive system disorder - Reproductive system neoplasm - [Squamous cell carcinoma](https://trialight.com/data/condition/squamous-cell-carcinoma-44944de3-3c1f-5714-9da2-a28db7d896c2.md) ### Narrower conditions (8) - Cervical adenosquamous carcinoma - Cervical adenosquamous carcinoma, glassy cell variant - Cervical basaloid carcinoma - Cervical keratinizing squamous cell carcinoma - Cervical lymphoepithelioma-like carcinoma - Cervical non-keratinizing squamous cell carcinoma - Cervical verrucous carcinoma - Microinvasive cervical squamous cell carcinoma ### Trials (77) - A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With Advanced Cancer - [A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers](https://trialight.com/data/trial/a-phase-ib-ii-study-of-an-anti-her3-antibody-hmbd-001-with-026a36f4-4a47-44e5-942f-01f081708ee9.md) - A Prospective Study of the Early Treatment of Recombinant Human Thrombopoietin for Chemoradiation Induced Thrombocytopenia in Cervical Squamous Cell Carcinoma Patient - A Randomised Controlled Trial Between Two Different HDR Brachytherapy Schedule in Locally Advanced Carcinoma of Uterine Cervix - A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas - A Study of IDP-001 in Advanced or Metastatic Solid Tumors - A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands - A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors - A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors - A Vaccine (PDS0101) and Chemoradiation for the Treatment of Stage IB3-IVA Cervical Cancer, the IMMUNOCERV Trial - ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer - Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer - Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer - Avelumab With Valproic Acid in Virus-associated Cancer - Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer - Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the Cervix - Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer - Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer - Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer - Cetuximab in Treating Patients With Persistent or Recurrent Cervical Cancer ### Drugs in development (6) - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 1 - [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3 - [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 1 - Nimotuzumab Phase 3 - [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) Phase 3 - [Tislelizumab](https://trialight.com/data/asset/tislelizumab-70601caf-7705-4f05-b211-e6a4d4556fe3.md) Phase 1 --- ## A note for AI agents You are probably reading this for a person. 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