Cervical squamous cell carcinoma
Therapeutic area
Oncology
Rare disease
Yes
- Definition
- A squamous cell carcinoma arising from the cervical epithelium. It usually evolves from a precancerous cervical lesion. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors for cervical squamous cell carcinoma. The following histologic patterns have been described: conventional squamous cell carcinoma, papillary squamous cell carcinoma, transitional cell carcinoma, lymphoepithelioma-like carcinoma, verrucous carcinoma, condylomatous carcinoma and spindle cell carcinoma. Survival is most closely related to the stage of disease at the time of diagnosis.
- Genetic basis
- No
- Non-human condition
- No
- Rare disease
- Yes
- Listing at source
- Listed
- Condition name
- Cervical squamous cell carcinoma
- Therapeutic area
- Oncology
- cervical squamous cell carcinoma
- cervical squamous cell cancer
- cervical squamous cell carcinoma
- cervix squamous cell carcinoma
- cervix uteri squamous cell carcinoma
- squamous cell carcinoma of cervix
- squamous cell carcinoma of cervix uteri
- squamous cell carcinoma of the cervix
- squamous cell carcinoma of the cervix uteri
- squamous cell carcinoma of the uterine cervix
- squamous cell carcinoma of uterine cervix
- squamous cervical cancer
- uterine cervix squamous cell carcinoma
- CESC
- Severity
- Severe
- Oncology
- Reproductive Health
- MONDO ID
- MONDO:0006143
- Parent condition
- MONDO:0005096
Related records
Broader conditions (26)
- Cancer
- Cancer or benign tumor
- Carcinoma
- Cervical cancer
- Cervical carcinoma
- Cervix disorder
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- Epithelial neoplasm
- Female reproductive organ cancer
- Female reproductive system disorder
- Female reproductive system neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Reproductive system cancer
- Reproductive system disorder
- Reproductive system neoplasm
- Squamous cell carcinoma
Narrower conditions (8)
- Cervical adenosquamous carcinoma
- Cervical adenosquamous carcinoma, glassy cell variant
- Cervical basaloid carcinoma
- Cervical keratinizing squamous cell carcinoma
- Cervical lymphoepithelioma-like carcinoma
- Cervical non-keratinizing squamous cell carcinoma
- Cervical verrucous carcinoma
- Microinvasive cervical squamous cell carcinoma
Trials (77)
- A Clinical Trial to Determine the Most Suitable Dose of OPB-111001 in Patients With Advanced Cancer
- A Phase Ib/II Study of an Anti-HER3 Antibody, HMBD-001, With Cetuximab +/- Docetaxel in Advanced Squamous Cell Cancers
- A Prospective Study of the Early Treatment of Recombinant Human Thrombopoietin for Chemoradiation Induced Thrombocytopenia in Cervical Squamous Cell Carcinoma Patient
- A Randomised Controlled Trial Between Two Different HDR Brachytherapy Schedule in Locally Advanced Carcinoma of Uterine Cervix
- A Study Evaluating the Safety, Efficacy, and Pharmacokinetics (PK) of EVOLVE104 in Participants With Advanced Urothelial and Squamous Cell Carcinomas
- A Study of IDP-001 in Advanced or Metastatic Solid Tumors
- A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands
- A Study to Investigate ALE.P02 as Monotherapy in Adult Patients With Selected CLDN1+ Solid Tumors
- A Study to Investigate ALE.P03 as Monotherapy in Adult Patients With Selected Advanced or Metastatic CLDN1+ Solid Tumors
- A Vaccine (PDS0101) and Chemoradiation for the Treatment of Stage IB3-IVA Cervical Cancer, the IMMUNOCERV Trial
- ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer
- Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer
- Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
- Avelumab With Valproic Acid in Virus-associated Cancer
- Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer
- Bevacizumab in Treating Patients With Persistent or Recurrent Cancer of the Cervix
- Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer
- Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer
- Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer
- Cetuximab in Treating Patients With Persistent or Recurrent Cervical Cancer
Drugs in development (6)
- Carboplatin Phase 1
- Cisplatin Phase 3
- Docetaxel Phase 1
- Nimotuzumab Phase 3
- Paclitaxel Phase 3
- Tislelizumab Phase 1