> Trialight public data. Index of pages: https://trialight.com/llms.txt
> Web page: https://trialight.com/data/condition/cervical-adenocarcinoma-013a4346-286c-5c50-bd25-66fde59ac6a0
> Record changed: 2026-10-13

# Cervical adenocarcinoma

Therapeutic area

Oncology

Rare disease

Yes

## Definition and classification

**Definition**

An adenocarcinoma arising from the cervical epithelium. It accounts for approximately 15% of invasive cervical carcinomas. Increased numbers of sexual partners and human papillomavirus (HPV) infection are risk factors. Grossly, advanced cervical adenocarcinoma may present as an exophytic mass, an ulcerated lesion, or diffuse cervical enlargement. Microscopically, the majority of cervical adenocarcinomas are of the endocervical (mucinous) type.

**Genetic basis**

No

**Non-human condition**

No

**Rare disease**

Yes

**Listing at source**

Listed

**Condition name**

Cervical adenocarcinoma

**Therapeutic area**

Oncology

### Alternative names (12)

- cervical adenocarcinoma
- adenocarcinoma - cervix
- adenocarcinoma of cervix
- adenocarcinoma of cervix uteri
- adenocarcinoma of the cervix
- adenocarcinoma of the cervix uteri
- adenocarcinoma of the uterine cervix
- adenocarcinoma of uterine cervix
- cervical adenocarcinoma
- cervix adenocarcinoma
- cervix uteri adenocarcinoma
- uterine cervix adenocarcinoma

## Clinical profile

**Severity**

Terminal

### All therapeutic areas (2)

- Oncology
- Reproductive Health

## Identifiers

**MONDO ID**

MONDO:0005153

Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0005153)

**Parent condition**

MONDO:0004970

## Related records

### Broader conditions (26)

- [Adenocarcinoma](https://trialight.com/data/condition/adenocarcinoma-b5c321d1-7c49-5bf9-abd0-dfa99dbd5f29.md)
- [Cancer](https://trialight.com/data/condition/cancer-703b1dfc-4812-50eb-83f4-d7a205d16bdb.md)
- Cancer or benign tumor
- [Carcinoma](https://trialight.com/data/condition/carcinoma-575e4c82-5fa5-5455-b1b7-30972eca1a2f.md)
- [Cervical cancer](https://trialight.com/data/condition/cervical-cancer-10fb8f6c-5aac-5281-8f06-7238adeec443.md)
- Cervical carcinoma
- Cervix disorder
- Disease
- Disease by body system or component
- Disease by etiologic mechanism
- [Epithelial neoplasm](https://trialight.com/data/condition/epithelial-neoplasm-5584692a-5e9d-58e1-9432-db6264993a80.md)
- [Female reproductive organ cancer](https://trialight.com/data/condition/female-reproductive-organ-cancer-1207d84e-931f-51b6-90d9-6b2135cdebbb.md)
- Female reproductive system disorder
- Female reproductive system neoplasm
- Glandular cell neoplasm
- Human disease
- Neoplasm
- Neoplastic disease or syndrome
- Reproductive system cancer
- Reproductive system disorder

### Narrower conditions (20)

- Cervical adenoid cystic carcinoma
- Cervical adenosquamous carcinoma
- Cervical adenosquamous carcinoma, glassy cell variant
- Cervical clear cell adenocarcinoma
- Cervical endometrioid adenocarcinoma
- Cervical mucinous adenocarcinoma
- Cervical mucinous adenocarcinoma, minimal deviation variant
- Cervical serous adenocarcinoma
- Cervical villoglandular adenocarcinoma
- Early invasive cervical adenocarcinoma
- Endocervical adenocarcinoma
- Endocervical type cervical mucinous adenocarcinoma
- Intestinal variant cervical mucinous adenocarcinoma
- Signet ring cell variant cervical mucinous adenocarcinoma
- Uterine ligament adenocarcinoma
- Uterine ligament clear cell adenocarcinoma
- Uterine ligament endometrioid adenocarcinoma
- Uterine ligament mucinous adenocarcinoma
- Uterine ligament serous adenocarcinoma
- Wolffian duct adenocarcinoma

### Trials (62)

- [A Study of \[225Ac\]Ac-AKY-1189 in Patients With Solid Tumors](https://trialight.com/data/trial/a-study-of-225ac-ac-aky-1189-in-patients-with-solid-tumors-a7bbe907-2877-44bf-89c8-692fa53772b4.md)
- A Study of Pemetrexed in Recurrent Cervical Adenocarcinomas
- ABI-007 in Treating Patients With Persistent or Recurrent Cervical Cancer
- Atezolizumab and Bevacizumab in Treating Patients With Recurrent, Persistent, or Metastatic Cervical Cancer
- Atezolizumab Before and/or With Chemoradiotherapy in Immune System Activation in Patients With Node Positive Stage IB2, II, IIIB, or IVA Cervical Cancer
- AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors
- Axalimogene Filolisbac (ADXS11-001) High Dose in Women With Human Papillomavirus (HPV) + Cervical Cancer
- Bevacizumab, Radiation Therapy, and Cisplatin in Treating Patients With Previously Untreated Locally Advanced Cervical Cancer
- Biospecimen Collection and Testing for the Prevalence of Anal Dysplasia and Anal Cancer in Patients With Cervical, Vaginal and Vulvar Dysplasia and Cancer
- Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer
- Capecitabine in Treating Patients With Persistent or Recurrent Cervical Cancer
- Cetuximab, Cisplatin, and Radiation Therapy in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer
- Chemoradiation Therapy and Ipilimumab in Treating Patients With Stages IB2-IIB or IIIB-IVA Cervical Cancer
- Cisplatin and Radiation Therapy Followed by Paclitaxel and Carboplatin in Treating Patients With Stage IB-IVA Cervical Cancer
- Cisplatin and Radiation Therapy With or Without Carboplatin and Paclitaxel in Patients With Locally Advanced Cervical Cancer
- Cisplatin and Radiation Therapy With or Without Tirapazamine in Treating Patients With Cervical Cancer
- Clinical Evaluation of Detection of High Risk HPV in Urine
- Collecting Tumor Samples From Patients With Gynecological Tumors
- Comparison of Four Combination Chemotherapy Regimens Using Cisplatin in Treating Patients With Stage IVB, Recurrent, or Persistent Cancer of the Cervix
- Complete Nerve-Sparing Radical Hysterectomy for Cervical Cancer

### Approved drugs (2)

- [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md)
- [Topotecan hydrochloride](https://trialight.com/data/asset/topotecan-hydrochloride-067505dc-01ca-47c0-99c9-0b8c89a1cb2b.md)

### Drugs in development (30)

- Berzosertib Phase 1
- Bintrafusp alfa Phase 2
- [Cadonilimab](https://trialight.com/data/asset/cadonilimab-3970701f-ffc8-4027-a97b-4e6c913803e6.md) Phase 3
- [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3
- [Celecoxib](https://trialight.com/data/asset/celecoxib-d2adc66b-f8fb-471f-8779-d55e35cdd52c.md) Phase 1
- [Cisplatin](https://trialight.com/data/asset/cisplatin-e039621a-d679-4740-88ac-94842bf4a91e.md) Phase 3
- Curcumin Phase 2
- [Docetaxel](https://trialight.com/data/asset/docetaxel-3c835086-a86f-4a89-abb6-45847fbab5d6.md) Phase 3
- Epoetin alfa Phase 3
- [Fludeoxyglucose F 18](https://trialight.com/data/asset/fludeoxyglucose-f-18-93dd95bf-cfbc-4452-b0ff-9cc0f4edc6ee.md) Phase 2
- [Gemcitabine](https://trialight.com/data/asset/gemcitabine-40c84c8f-1f08-4402-bce9-f31ff283382e.md) Phase 3
- Gemcitabine hydrochloride Phase 3
- [Ipilimumab](https://trialight.com/data/asset/ipilimumab-06c42b29-e333-4f3c-94fe-dbea5fe48cd4.md) Phase 2
- Irinotecan Phase 3
- [Letrozole](https://trialight.com/data/asset/letrozole-67319198-7e88-4130-b185-d776c835863c.md) Phase 2
- Metformin Phase 2
- Nintedanib Phase 2
- [Nivolumab](https://trialight.com/data/asset/nivolumab-d2e207ca-a7d1-43d0-987f-43ef7eef8f1b.md) Phase 2
- [Paclitaxel](https://trialight.com/data/asset/paclitaxel-889db92c-df97-46a6-bf1c-74974a87fa75.md) Phase 3
- [Pembrolizumab](https://trialight.com/data/asset/pembrolizumab-f9ac1934-47a5-4a53-ae55-20b7d53d8815.md) Phase 3

---

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