> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/central-nervous-system-neoplasm-bd35c306-06e5-549c-a882-45bdfbcbb7d8 > Record changed: 2026-10-13 # Central nervous system neoplasm Therapeutic area Neurology Rare disease No ## Definition and classification **Definition** A benign or malignant, primary or metastatic neoplasm that affects the brain, meninges, or spinal cord. Representative examples of primary neoplasms include astrocytoma, oligodendroglioma, ependymoma, and meningioma. Representative examples of metastatic neoplasms include carcinoma and leukemia. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Central nervous system neoplasm **Therapeutic area** Neurology ### Alternative names (21) - central nervous system neoplasm - CNS neoplasm - CNS tumor - CNS tumour - brain/spinal cord tumor - brain/spinal cord tumour - central nervous system neoplasm - central nervous system neoplasm (disease) - central nervous system tumor - central nervous system tumour - neoplasm of CNS - neoplasm of central nervous system - neoplasm of the central nervous system - tumor of CNS - tumor of central nervous system - tumor of the CNS - tumor of the central nervous system - tumour of CNS - tumour of central nervous system - tumour of the CNS - tumour of the central nervous system ## Clinical profile **Severity** Severe ### All therapeutic areas (2) - Neurology - Oncology ## Identifiers **MONDO ID** MONDO:0006130 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0006130) **Parent condition** MONDO:0002602 ## Related records ### Broader conditions (10) - Cancer or benign tumor - [Central nervous system disorder](https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964.md) - Disease - Disease by body system or component - Disease by etiologic mechanism - Human disease - Neoplasm - Neoplastic disease or syndrome - Nervous system disorder - Nervous system neoplasm ### Narrower conditions (504) - ACTH-producing pituitary gland adenoma - ACTH-producing pituitary gland carcinoma - ACTH-producing pituitary gland neoplasm - [Adamantinous craniopharyngioma](https://trialight.com/data/condition/adamantinous-craniopharyngioma-1508b40a-dc32-58a9-9779-53dc9d409a3d.md) - Adrenal gland pheochromocytoma - Adult anaplastic ependymoma - Adult brain ependymoma - Adult brain stem neoplasm - Adult brainstem astrocytoma - Adult brainstem glioma - Adult brainstem gliosarcoma - Adult brainstem mixed glioma - Adult central nervous system choriocarcinoma - Adult central nervous system embryonal carcinoma - Adult central nervous system germ cell tumor - Adult central nervous system germinoma - Adult central nervous system immature teratoma - Adult central nervous system mature teratoma - Adult central nervous system mixed germ cell tumor - Adult central nervous system primitive neuroectodermal neoplasm ### Trials (696) - 18-F-Fluoroacetate as PET Imaging Agent - 3'-Deoxy-3'-\[18F\] Fluorothymidine PET Imaging in Patients With Cancer - 5-Aminolevulinic Acid (5-ALA) Gliolan®: Usage Increase Proposal for Neurosurgical Procedures in High-Grade Gliomas - 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. - A Clinical Prediction Model for Surgical Site Infection After Central Nervous System Tumor Surgery - A Feasibility, Dose-Escalation Study Using Intracerebral Microdialysis to Assess the Neuropharmacodynamics of Temsirolimus in Patients With Primary or Metastatic Brain Tumors - A FIH Study of PF-07284890 in Participants With BRAF V600 Mutant Solid Tumors With and Without Brain Involvement - A Multi-Center Phase I Study of Intravenous Deforolimus (AP23573, MK-8669) Administered QDX5 Every Other Week in Pediatric Patients With Advanced Solid Tumors (8669-028)(COMPLETED) - A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. - A Phase 1b / 2 Drug Resistant Immunotherapy With Activated, Gene Modified Allogeneic or Autologous γδ T Cells (DeltEx) in Combination With Maintenance Temozolomide in Subjects With Recurrent or Newly Diagnosed Glioblastoma - A Phase I Trial Using Combination Irinotecan and Thalidomide for Recurrent CNS Tumors - A Pilot Study of 18F-FLT in Pediatric Patients With Central Nervous System (CNS) Tumors - A Study Assessing Pamiparib With Radiation and/or Temozolomide (TMZ) in Participants With Newly Diagnosed or Recurrent Glioblastoma - A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors - A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects - A Study of Avapritinib in Pediatric Patients With Solid Tumors Dependent on KIT or PDGFRA Signaling - A Study of Avutometinib for People With Solid Tumor Cancers - A Study of Intravenous EEDVsMit in Children With Recurrent / Refractory Solid or CNS Tumours Expressing EGFR - A Study of Metabolic Agents Following Brain Radiation - A Study of Mirdametinib in People With Central Nervous System Tumors ### Drugs in development (151) - 6-O-benzylguanine Phase 2 - Acridine Phase 2 - AEE-788 Phase 1 - Alanosine Phase 1 - [Albumin human](https://trialight.com/data/asset/albumin-human-95414b67-0d38-49d4-91b2-27b1c6c17389.md) Phase 1 - [Alcohol](https://trialight.com/data/asset/alcohol-94acdb16-f595-4fd2-a9fa-0e1509bc9a8f.md) Phase 2 - Aldesleukin Phase 2 - Amifostine Phase 2 - Arsenic trioxide Phase 1 - ATN-161 Phase 1 - Atrasentan hydrochloride Phase 1 - [Avelumab](https://trialight.com/data/asset/avelumab-7197343d-e77c-45d7-978a-ad6cf91f6437.md) Phase 1 - Bemcentinib Early phase 1 - [Bevacizumab](https://trialight.com/data/asset/bevacizumab-a9e09d09-2d3c-4fda-ad45-01fd000dd363.md) Phase 2 - Bleomycin Phase 2 - Busulfan Phase 2 - Calcitriol Phase 1 - [Capecitabine](https://trialight.com/data/asset/capecitabine-a5be3dfa-a85f-4c85-8c62-f4ceb74e5f99.md) Phase 1 - [Carboplatin](https://trialight.com/data/asset/carboplatin-91aa6947-1cbb-486a-b5c6-aaaa6868e24e.md) Phase 3 - Carmustine Phase 3 --- ## A note for AI agents You are probably reading this for a person. 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