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Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/central-nervous-system-disorder-78230ae5-4e6b-5495-ac04-050b0e11e964 > Record changed: 2026-10-13 # Central nervous system disorder Therapeutic area Neurology Rare disease No ## Definition and classification **Definition** A disease involving the central nervous system. **Genetic basis** No **Non-human condition** No **Rare disease** No **Listing at source** Listed **Condition name** Central nervous system disorder **Therapeutic area** Neurology ### Alternative names (10) - central nervous system disorder - CNS disorder - central nervous disease - central nervous system disease - central nervous system disease or disorder - central nervous system disorder - disease of central nervous system - disease of the central nervous system - disease or disorder of central nervous system - disorder of central nervous system ## Clinical profile **All therapeutic areas** - Neurology **Severity** Unknown ## Identifiers **MONDO ID** MONDO:0002602 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0002602) **Parent condition** MONDO:0005071 ## Related records ### Broader conditions (4) - Disease - Disease by body system or component - Human disease - Nervous system disorder ### Narrower conditions (2,560) - AARS1-related leukoencephalopathy - ABeta amyloidosis, Arctic type - ABeta amyloidosis, dutch type - ABeta amyloidosis, Iowa type - ABeta amyloidosis, Italian type - ABetaA21G amyloidosis - ABetaL34V amyloidosis - Abetalipoproteinemia - ABri amyloidosis - Aceruloplasminemia - ACO2-related optic atrophy with or without extraocular features - Acquired aneurysmal subarachnoid hemorrhage - Acquired Creutzfeldt-Jakob disease - Acquired developmental and epileptic encephalopathy - Acquired human prion disease - Acquired hyperprolactinemia - Acquired motor neuron disease - Acquired pituitary hormone deficiency - Acquired porencephaly - Acquired schizencephaly ### Trials (418) - 12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI) - 131I-omburtamab for the Treatment of Central Nervous System/Leptomeningeal Neoplasms in Children and Young Adults - 1H Magnetic Resonance Spectroscopy in Migraine Patients - 2-Part Multiple Ascending Dose Study for Safety and Pharmacokinetics in Healthy and Elderly Subjects - 4D-310 in Adults With Fabry Disease and Cardiac Involvement - A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome - A 24-weeks, Multi-center, Randomized, Double-blind, Placebo Controlled Study to Evaluate the Efficacy and Safety of Donepezil Hydrochloride in Chinese Subjects With Severe Alzheimer's Disease - A Bridging Study on Efficacy and Safety of \[18F\]Florbetaben PET for Diagnosis of Alzheimer Disease Subjects in Chinese Population - A Clinical Study to Evaluate the Drug Interaction Between YZJ-1139 Tablets and Escitalopram Oxalate Tablets - A Clinical Trial of PRAX-114 in Participants With Essential Tremor - A Dose-finding Study to Evaluate mRNA-3210 in Participants With Phenylketonuria - A Drug-drug Interaction Study of Avapritinib and Midazolam - A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease - A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT) - A Home-Based Approach Study to Evaluate the Efficacy and Safety of Alectinib in Locally-Advanced or Metastatic ALK-Positive Solid Tumors - A Long-Term Open-Label Study of ML-007C-MA in Adults With Schizophrenia - A Longitudinal Study of Amyotrophic Lateral Sclerosis (ALS) Biomarkers - A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China - A Multicenter Study of Ultrafast Pulse Wave Velocity in Obese Chinese Han Adults - A Multicenter, Open-label, Pilot Study of Soticlestat (TAK-935/OV935) in Participants With 15Q Duplication Syndrome (Dup 15q) or Cyclin-Dependent Kinase-Like 5 (CDKL5) Deficiency Disorder (ARCADE STUDY) ### Drugs in development (10) - Donepezil Phase 1 - Encenicline Phase 1 - Enzastaurin Phase 1 - Gadobutrol Phase 3 - Gadopiclenol Phase 2 - Gadoterate meglumine Phase 3 - Gadoteridol Phase 3 - Memantine Phase 1 - Rivastigmine Phase 1 - Tasadenoturev Phase 1 ### Other linked drugs (5) - Gadodiamide - Metrizamide - Protirelin - Taltirelin - Technetium TC 99M bicisate --- ## A note for AI agents You are probably reading this for a person. 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