> Trialight public data. Index of pages: https://trialight.com/llms.txt > Web page: https://trialight.com/data/condition/cardiomyopathy-f867c8a5-a3a9-513d-a7ca-7e2d05ad56d3 > Record changed: 2026-10-13 # Cardiomyopathy Therapeutic area Cardiology Rare disease Yes ## Definition and classification **Definition** A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive. **Genetic basis** No **Non-human condition** No **Rare disease** Yes **Listing at source** Listed **Condition name** Cardiomyopathy **Therapeutic area** Cardiology ### Alternative names (3) - cardiomyopathy - Cardiomyopathies - cardiomyopathy ## Clinical profile **Severity** Severe ### All therapeutic areas (3) - Cardiology - Neuromuscular Disease - Rheumatology ## Identifiers **MONDO ID** MONDO:0004994 Source: [monarchinitiative.org](https://monarchinitiative.org/MONDO:0004994) **Parent condition** MONDO:0003939 ## Related records ### Broader conditions (7) - [Cardiovascular disorder](https://trialight.com/data/condition/cardiovascular-disorder-362e433e-88a4-575f-90af-50fe7239dec0.md) - Disease - Disease by body system or component - Heart disorder - Human disease - Muscle tissue disorder - Musculoskeletal system disorder ### Narrower conditions (287) - 46,XY complete gonadal dysgenesis - 46,XY disorder of sex development due to testicular 17,20-desmolase deficiency - 46,XY gonadal dysgenesis-motor and sensory neuropathy syndrome - 46,XY sex reversal 1 - 46,XY sex reversal 10 - 46,XY sex reversal 11 - 46,XY sex reversal 2 - 46,XY sex reversal 3 - 46,XY sex reversal 4 - 46,XY sex reversal 5 - 46,XY sex reversal 6 - 46,XY sex reversal 7 - 46,XY sex reversal 9 - AA amyloidosis - Acute myocarditis - AL amyloidosis - Alcoholic cardiomyopathy - Arrhythmogenic right ventricular cardiomyopathy - Arrhythmogenic right ventricular dysplasia 1 - Arrhythmogenic right ventricular dysplasia 10 ### Trials (553) - 123-I mIBG (AdreView) Heart-to-Mediastinal (H/M) Ratio and SPECT Imaging on a Small Field of View-High Efficiency Cardiac SPECT System - A Bioequivalence Study of Two Formulations of HRS-1893 Tablets in Healthy Participants - A Comparative Study of Subjects Past Their Final Follow-ON Visit - A Comparison of Magnetic Resonance Imaging in Persons With Heart Failure to Health, Aged Matched Controls - A Extension Study to Evaluate Revusiran (ALN-TTRSC) in Patients With Transthyretin (TTR) Cardiac Amyloidosis - A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease - A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy - A Phase 1 Safety Study of the Intravenous Administration of Thymosin Beta in Healthy Volunteers - A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure - A Phase 2 Open-label Pilot Study Evaluating MYK-461 in Subjects With Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction - A Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of CT-G20 in Subjects With Obstructive Hypertrophic Cardiomyopathy - A Phase I Trial on the Relative Bioavailability and Food Effect of HRS-1893 Tablets in Healthy Subjects - A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy - A PILOT Study on LSGB vs EMB in the Diagnosis of Cardiac Transthyretin Amyloidosis - A Preventive, Multidisciplinary Primary Care Intervention Organized Around a Therapeutic Garden: Acceptability to Patients Suffering from Cardio-neurovascular Pathology and to Those Involved in the Action. - A Psychoeducational Intervention Supporting Patients With an Inherited Cardiac Condition - A Safety Study Comparing Natrecor (Nesiritide) Versus Dobutamine Therapy for Worsening Congestive Heart Failure - A Study About the Natural History in Adults With BAG3 Dilated Cardiomyopathy (a Type of Heart Disease) (BAG3 DCM) - A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter - A Study of ARRY-371797 (PF-07265803) in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation ### Approved drugs (4) - Acoramidis hydrochloride - Dexrazoxane hydrochloride - Tafamidis - Tafamidis meglumine ### Drugs in development (21) - Adenosine Phase 2 - Aficamten Phase 1 - Amiodarone Phase 3 - Atorvastatin Phase 2 - Azathioprine Phase 3 - Carvedilol Phase 2 - Emprumapimod Phase 1 - Enalapril Phase 3 - Eplerenone Phase 3 - Flutemetamol F 18 Phase 1 - [Human immunoglobulin G](https://trialight.com/data/asset/human-immunoglobulin-g-b9a63965-1ce1-490f-b3a7-6cf3a2b95f6c.md) Phase 3 - Interferon beta-1B Phase 2 - Lisinopril anhydrous Phase 2 - Melatonin Phase 3 - Mycophenolate mofetil Phase 2 - Nesiritide Phase 3 - Pravastatin Phase 2 - [Prednisolone](https://trialight.com/data/asset/prednisolone-783fce19-b285-4835-90c3-3db5a6364414.md) Phase 2 - [Prednisone](https://trialight.com/data/asset/prednisone-a5a99f90-5fbe-45c2-a625-34ba78735da6.md) Phase 3 - Sotagliflozin Early phase 1 ### Other linked drugs (1) - Ranolazine --- ## A note for AI agents You are probably reading this for a person. 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